Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MORF4L2 (mortality factor 4 like 2)

Identity

Alias_symbol (synonym)KIAA0026
MRGX
Other aliasMORFL2
HGNC (Hugo) MORF4L2
LocusID (NCBI) 9643
Atlas_Id 50257
Location Xq22.2  [Link to chromosome band Xq22]
Location_base_pair Starts at 102930426 and ends at 102941746 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MORF4L2 (Xq22.2) / FST (5q11.2)MORF4L2 (Xq22.2) / GLRA4 (Xq22.2)MORF4L2 (Xq22.2) / GNB1 (1p36.33)
MORF4L2 Xq22.2 / GLRA4 Xq22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MORF4L2   16849
Cards
Entrez_Gene (NCBI)MORF4L2  9643  mortality factor 4 like 2
AliasesMORFL2; MRGX
GeneCards (Weizmann)MORF4L2
Ensembl hg19 (Hinxton)ENSG00000123562 [Gene_View]  chrX:102930426-102941746 [Contig_View]  MORF4L2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000123562 [Gene_View]  chrX:102930426-102941746 [Contig_View]  MORF4L2 [Vega]
ICGC DataPortalENSG00000123562
TCGA cBioPortalMORF4L2
AceView (NCBI)MORF4L2
Genatlas (Paris)MORF4L2
WikiGenes9643
SOURCE (Princeton)MORF4L2
Genetics Home Reference (NIH)MORF4L2
Genomic and cartography
GoldenPath hg19 (UCSC)MORF4L2  -     chrX:102930426-102941746 -  Xq22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MORF4L2  -     Xq22.2   [Description]    (hg38-Dec_2013)
EnsemblMORF4L2 - Xq22.2 [CytoView hg19]  MORF4L2 - Xq22.2 [CytoView hg38]
Mapping of homologs : NCBIMORF4L2 [Mapview hg19]  MORF4L2 [Mapview hg38]
OMIM300409   
Gene and transcription
Genbank (Entrez)AB050778 AB050779 AF100620 AF167174 AK056012
RefSeq transcript (Entrez)NM_001142418 NM_001142419 NM_001142420 NM_001142421 NM_001142422 NM_001142423 NM_001142424 NM_001142425 NM_001142426 NM_001142427 NM_001142428 NM_001142429 NM_001142430 NM_001142431 NM_001142432 NM_012286
RefSeq genomic (Entrez)NC_000023 NC_018934 NT_011651 NW_004929444
Consensus coding sequences : CCDS (NCBI)MORF4L2
Cluster EST : UnigeneHs.326387 [ NCBI ]
CGAP (NCI)Hs.326387
Alternative Splicing GalleryENSG00000123562
Gene ExpressionMORF4L2 [ NCBI-GEO ]   MORF4L2 [ EBI - ARRAY_EXPRESS ]   MORF4L2 [ SEEK ]   MORF4L2 [ MEM ]
Gene Expression Viewer (FireBrowse)MORF4L2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9643
GTEX Portal (Tissue expression)MORF4L2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15014   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15014  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15014
Splice isoforms : SwissVarQ15014
PhosPhoSitePlusQ15014
Domaine pattern : Prosite (Expaxy)MRG (PS51640)   
Domains : Interpro (EBI)MRG    MRG_dom   
Domain families : Pfam (Sanger)MRG (PF05712)   
Domain families : Pfam (NCBI)pfam05712   
Conserved Domain (NCBI)MORF4L2
DMDM Disease mutations9643
Blocks (Seattle)MORF4L2
SuperfamilyQ15014
Human Protein AtlasENSG00000123562
Peptide AtlasQ15014
HPRD02326
IPIIPI00014174   IPI00644869   IPI00645275   IPI00645843   IPI00645503   IPI00646810   
Protein Interaction databases
DIP (DOE-UCLA)Q15014
IntAct (EBI)Q15014
FunCoupENSG00000123562
BioGRIDMORF4L2
STRING (EMBL)MORF4L2
ZODIACMORF4L2
Ontologies - Pathways
QuickGOQ15014
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  nucleoplasm  nucleolus  plasma membrane  DNA repair  chromatin remodeling  chromatin silencing  transcription, DNA-templated  histone deacetylation  NuA4 histone acetyltransferase complex  regulation of growth  histone H4 acetylation  histone H2A acetylation  positive regulation of transcription from RNA polymerase II promoter  positive regulation of striated muscle cell differentiation  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  nucleoplasm  nucleolus  plasma membrane  DNA repair  chromatin remodeling  chromatin silencing  transcription, DNA-templated  histone deacetylation  NuA4 histone acetyltransferase complex  regulation of growth  histone H4 acetylation  histone H2A acetylation  positive regulation of transcription from RNA polymerase II promoter  positive regulation of striated muscle cell differentiation  
NDEx NetworkMORF4L2
Atlas of Cancer Signalling NetworkMORF4L2
Wikipedia pathwaysMORF4L2
Orthology - Evolution
OrthoDB9643
GeneTree (enSembl)ENSG00000123562
Phylogenetic Trees/Animal Genes : TreeFamMORF4L2
HOVERGENQ15014
HOGENOMQ15014
Homologs : HomoloGeneMORF4L2
Homology/Alignments : Family Browser (UCSC)MORF4L2
Gene fusions - Rearrangements
Fusion : MitelmanMORF4L2/GLRA4 [Xq22.2/Xq22.2]  
Fusion: TCGAMORF4L2 Xq22.2 GLRA4 Xq22.2 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMORF4L2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MORF4L2
dbVarMORF4L2
ClinVarMORF4L2
1000_GenomesMORF4L2 
Exome Variant ServerMORF4L2
ExAC (Exome Aggregation Consortium)MORF4L2 (select the gene name)
Genetic variants : HAPMAP9643
Genomic Variants (DGV)MORF4L2 [DGVbeta]
DECIPHER (Syndromes)X:102930426-102941746  ENSG00000123562
CONAN: Copy Number AnalysisMORF4L2 
Mutations
ICGC Data PortalMORF4L2 
TCGA Data PortalMORF4L2 
Broad Tumor PortalMORF4L2
OASIS PortalMORF4L2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMORF4L2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMORF4L2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MORF4L2
DgiDB (Drug Gene Interaction Database)MORF4L2
DoCM (Curated mutations)MORF4L2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MORF4L2 (select a term)
intoGenMORF4L2
Cancer3DMORF4L2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300409   
Orphanet
MedgenMORF4L2
Genetic Testing Registry MORF4L2
NextProtQ15014 [Medical]
TSGene9643
GENETestsMORF4L2
Huge Navigator MORF4L2 [HugePedia]
snp3D : Map Gene to Disease9643
BioCentury BCIQMORF4L2
ClinGenMORF4L2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9643
Chemical/Pharm GKB GenePA134925837
Clinical trialMORF4L2
Miscellaneous
canSAR (ICR)MORF4L2 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMORF4L2
EVEXMORF4L2
GoPubMedMORF4L2
iHOPMORF4L2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 13:17:15 CET 2017

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