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MOV10 (Mov10 RISC complex RNA helicase)

Identity

Alias (NCBI)fSAP113
gb110
HGNC (Hugo) MOV10
HGNC Alias symbgb110
MGC2948
fSAP113
HGNC Alias namefunctional spliceosome-associated protein 113
HGNC Previous nameMov10 (Moloney leukemia virus 10, mouse) homolog
 Mov10, Moloney leukemia virus 10, homolog (mouse)
LocusID (NCBI) 4343
Atlas_Id 41415
Location 1p13.2  [Link to chromosome band 1p13]
Location_base_pair Starts at 112674312 and ends at 112700746 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HSPG2 (1p36.12) / MOV10 (1p13.2)MOV10 (1p13.2) / MOV10 (1p13.2)TRIO (5p15.2) / MOV10 (1p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MOV10   7200
Cards
Entrez_Gene (NCBI)MOV10    Mov10 RISC complex RNA helicase
AliasesfSAP113; gb110
GeneCards (Weizmann)MOV10
Ensembl hg19 (Hinxton)ENSG00000155363 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000155363 [Gene_View]  ENSG00000155363 [Sequence]  chr1:112674312-112700746 [Contig_View]  MOV10 [Vega]
ICGC DataPortalENSG00000155363
TCGA cBioPortalMOV10
AceView (NCBI)MOV10
Genatlas (Paris)MOV10
SOURCE (Princeton)MOV10
Genetics Home Reference (NIH)MOV10
Genomic and cartography
GoldenPath hg38 (UCSC)MOV10  -     chr1:112674312-112700746 +  1p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MOV10  -     1p13.2   [Description]    (hg19-Feb_2009)
GoldenPathMOV10 - 1p13.2 [CytoView hg19]  MOV10 - 1p13.2 [CytoView hg38]
ImmunoBaseENSG00000155363
Genome Data Viewer NCBIMOV10 [Mapview hg19]  
OMIM610742   
Gene and transcription
Genbank (Entrez)AB046851 AK023297 AK057353 AK074174 AK226011
RefSeq transcript (Entrez)NM_001130079 NM_001286072 NM_001321324 NM_001369507 NM_001389562 NM_001389563 NM_020963
Consensus coding sequences : CCDS (NCBI)MOV10
Gene ExpressionMOV10 [ NCBI-GEO ]   MOV10 [ EBI - ARRAY_EXPRESS ]   MOV10 [ SEEK ]   MOV10 [ MEM ]
Gene Expression Viewer (FireBrowse)MOV10 [ Firebrowse - Broad ]
GenevisibleExpression of MOV10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4343
GTEX Portal (Tissue expression)MOV10
Human Protein AtlasENSG00000155363-MOV10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HCE1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HCE1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HCE1
PhosPhoSitePlusQ9HCE1
Domains : Interpro (EBI)DNA2/NAM7-like_C    MOV-10    P-loop_NTPase   
Domain families : Pfam (Sanger)AAA_12 (PF13087)   
Domain families : Pfam (NCBI)pfam13087   
Conserved Domain (NCBI)MOV10
SuperfamilyQ9HCE1
AlphaFold pdb e-kbQ9HCE1   
Human Protein Atlas [tissue]ENSG00000155363-MOV10 [tissue]
HPRD14732
Protein Interaction databases
DIP (DOE-UCLA)Q9HCE1
IntAct (EBI)Q9HCE1
BioGRIDMOV10
STRING (EMBL)MOV10
ZODIACMOV10
Ontologies - Pathways
QuickGOQ9HCE1
Ontology : AmiGOP-body  RNA binding  RNA binding  RNA binding  protein binding  ATP binding  extracellular space  nucleus  cytosol  cytosol  cytosol  Wnt signaling pathway, calcium modulating pathway  cytoplasmic stress granule  negative regulation of transposition, RNA-mediated  positive regulation of gene expression  negative regulation of gene expression  hydrolase activity  intracellular receptor signaling pathway  5'-3' RNA helicase activity  post-transcriptional gene silencing by RNA  gene silencing by miRNA  mRNA cleavage involved in gene silencing by miRNA  cytoplasmic ribonucleoprotein granule  P granule  regulation of megakaryocyte differentiation  defense response to virus  regulation of transcription initiation from RNA polymerase II promoter  positive regulation of mRNA catabolic process  3'-UTR-mediated mRNA destabilization  regulation of neuron projection arborization  
Ontology : EGO-EBIP-body  RNA binding  RNA binding  RNA binding  protein binding  ATP binding  extracellular space  nucleus  cytosol  cytosol  cytosol  Wnt signaling pathway, calcium modulating pathway  cytoplasmic stress granule  negative regulation of transposition, RNA-mediated  positive regulation of gene expression  negative regulation of gene expression  hydrolase activity  intracellular receptor signaling pathway  5'-3' RNA helicase activity  post-transcriptional gene silencing by RNA  gene silencing by miRNA  mRNA cleavage involved in gene silencing by miRNA  cytoplasmic ribonucleoprotein granule  P granule  regulation of megakaryocyte differentiation  defense response to virus  regulation of transcription initiation from RNA polymerase II promoter  positive regulation of mRNA catabolic process  3'-UTR-mediated mRNA destabilization  regulation of neuron projection arborization  
NDEx NetworkMOV10
Atlas of Cancer Signalling NetworkMOV10
Wikipedia pathwaysMOV10
Orthology - Evolution
OrthoDB4343
GeneTree (enSembl)ENSG00000155363
Phylogenetic Trees/Animal Genes : TreeFamMOV10
Homologs : HomoloGeneMOV10
Homology/Alignments : Family Browser (UCSC)MOV10
Gene fusions - Rearrangements
Fusion : QuiverMOV10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMOV10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MOV10
dbVarMOV10
ClinVarMOV10
MonarchMOV10
1000_GenomesMOV10 
Exome Variant ServerMOV10
GNOMAD BrowserENSG00000155363
Varsome BrowserMOV10
ACMGMOV10 variants
VarityQ9HCE1
Genomic Variants (DGV)MOV10 [DGVbeta]
DECIPHERMOV10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMOV10 
Mutations
ICGC Data PortalMOV10 
TCGA Data PortalMOV10 
Broad Tumor PortalMOV10
OASIS PortalMOV10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMOV10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMOV10
Mutations and Diseases : HGMDMOV10
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMOV10
DgiDB (Drug Gene Interaction Database)MOV10
DoCM (Curated mutations)MOV10
CIViC (Clinical Interpretations of Variants in Cancer)MOV10
Cancer3DMOV10
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610742   
Orphanet
DisGeNETMOV10
MedgenMOV10
Genetic Testing Registry MOV10
NextProtQ9HCE1 [Medical]
GENETestsMOV10
Target ValidationMOV10
Huge Navigator MOV10 [HugePedia]
ClinGenMOV10
Clinical trials, drugs, therapy
MyCancerGenomeMOV10
Protein Interactions : CTDMOV10
Pharm GKB GenePA30908
PharosQ9HCE1
Clinical trialMOV10
Miscellaneous
canSAR (ICR)MOV10
HarmonizomeMOV10
DataMed IndexMOV10
Probes
Litterature
PubMed128 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMOV10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:21:10 CEST 2021

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