MOV10 (Mov10 RISC complex RNA helicase)

2003-11-01  

Identity

HGNC
LOCATION
1p13.2
LOCUSID
ALIAS
fSAP113,gb110
FUSION GENES

Other Information

Locus ID:

NCBI: 4343
MIM: 610742
HGNC: 7200
Ensembl: ENSG00000155363

Variants:

dbSNP: 4343
ClinVar: 4343
TCGA: ENSG00000155363
COSMIC: MOV10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000155363ENST00000357443Q9HCE1
ENSG00000155363ENST00000369644Q5JR04
ENSG00000155363ENST00000369645Q9HCE1
ENSG00000155363ENST00000413052Q9HCE1

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Signaling by the B Cell Receptor (BCR)REACTOMER-HSA-983705
Downstream signaling events of B Cell Receptor (BCR)REACTOMER-HSA-1168372
PIP3 activates AKT signalingREACTOMER-HSA-1257604
Innate Immune SystemREACTOMER-HSA-168249
DAP12 interactionsREACTOMER-HSA-2172127
DAP12 signalingREACTOMER-HSA-2424491
Fc epsilon receptor (FCERI) signalingREACTOMER-HSA-2454202
Role of LAT2/NTAL/LAB on calcium mobilizationREACTOMER-HSA-2730905
Signal TransductionREACTOMER-HSA-162582
Signaling by EGFRREACTOMER-HSA-177929
GAB1 signalosomeREACTOMER-HSA-180292
Signalling by NGFREACTOMER-HSA-166520
NGF signalling via TRKA from the plasma membraneREACTOMER-HSA-187037
PI3K/AKT activationREACTOMER-HSA-198203
Signaling by PDGFREACTOMER-HSA-186797
Downstream signal transductionREACTOMER-HSA-186763
Signaling by SCF-KITREACTOMER-HSA-1433557
MAPK family signaling cascadesREACTOMER-HSA-5683057
MAPK6/MAPK4 signalingREACTOMER-HSA-5687128
Signaling by NOTCHREACTOMER-HSA-157118
Pre-NOTCH Expression and ProcessingREACTOMER-HSA-1912422
Pre-NOTCH Transcription and TranslationREACTOMER-HSA-1912408
Signaling by WntREACTOMER-HSA-195721
Beta-catenin independent WNT signalingREACTOMER-HSA-3858494
Ca2+ pathwayREACTOMER-HSA-4086398
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
TP53 Regulates Metabolic GenesREACTOMER-HSA-5628897
Cellular responses to stressREACTOMER-HSA-2262752
Cellular SenescenceREACTOMER-HSA-2559583
Oncogene Induced SenescenceREACTOMER-HSA-2559585
Oxidative Stress Induced SenescenceREACTOMER-HSA-2559580

References

Pubmed IDYearTitleCitations
374370582023MOV10 recruits DCP2 to decap human LINE-1 RNA by forming large cytoplasmic granules with phase separation properties.3
374370582023MOV10 recruits DCP2 to decap human LINE-1 RNA by forming large cytoplasmic granules with phase separation properties.3
334915172022Association study of hypertension susceptibility genes ITGA9, MOV10, and CACNB2 with preeclampsia in Chinese Han population.0
334915172022Association study of hypertension susceptibility genes ITGA9, MOV10, and CACNB2 with preeclampsia in Chinese Han population.0
332695452021The association of MOV10 polymorphism and expression levels with preeclampsia in the Chinese Han population.1
340655122021CRL4-DCAF12 Ubiquitin Ligase Controls MOV10 RNA Helicase during Spermatogenesis and T Cell Activation.9
332695452021The association of MOV10 polymorphism and expression levels with preeclampsia in the Chinese Han population.1
340655122021CRL4-DCAF12 Ubiquitin Ligase Controls MOV10 RNA Helicase during Spermatogenesis and T Cell Activation.9
306172212019MOV10 sequesters the RNP of influenza A virus in the cytoplasm and is antagonized by viral NS1 protein.14
306217212019MOV10 binding circ-DICER1 regulates the angiogenesis of glioma via miR-103a-3p/miR-382-5p mediated ZIC4 expression change.56
317229672019The MOV10 helicase restricts hepatitis B virus replication by inhibiting viral reverse transcription.13
306172212019MOV10 sequesters the RNP of influenza A virus in the cytoplasm and is antagonized by viral NS1 protein.14
306217212019MOV10 binding circ-DICER1 regulates the angiogenesis of glioma via miR-103a-3p/miR-382-5p mediated ZIC4 expression change.56
317229672019The MOV10 helicase restricts hepatitis B virus replication by inhibiting viral reverse transcription.13
293154042018Interplay between RNASEH2 and MOV10 controls LINE-1 retrotransposition.35

Citation

Dessen P

MOV10 (Mov10 RISC complex RNA helicase)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/41415/mov10