Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MPC1 (mitochondrial pyruvate carrier 1)

Identity

Alias_namesBRP44L
brain protein 44-like
Alias_symbol (synonym)dJ68L15.3
CGI-129
Other aliasMPYCD
SLC54A1
HGNC (Hugo) MPC1
LocusID (NCBI) 51660
Atlas_Id 55114
Location 6q27  [Link to chromosome band 6q27]
Location_base_pair Starts at 166364920 and ends at 166383013 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MPC1   21606
Cards
Entrez_Gene (NCBI)MPC1  51660  mitochondrial pyruvate carrier 1
AliasesBRP44L; CGI-129; MPYCD; SLC54A1
GeneCards (Weizmann)MPC1
Ensembl hg19 (Hinxton)ENSG00000060762 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000060762 [Gene_View]  ENSG00000060762 [Sequence]  chr6:166364920-166383013 [Contig_View]  MPC1 [Vega]
ICGC DataPortalENSG00000060762
TCGA cBioPortalMPC1
AceView (NCBI)MPC1
Genatlas (Paris)MPC1
WikiGenes51660
SOURCE (Princeton)MPC1
Genetics Home Reference (NIH)MPC1
Genomic and cartography
GoldenPath hg38 (UCSC)MPC1  -     chr6:166364920-166383013 -  6q27   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MPC1  -     6q27   [Description]    (hg19-Feb_2009)
EnsemblMPC1 - 6q27 [CytoView hg19]  MPC1 - 6q27 [CytoView hg38]
Mapping of homologs : NCBIMPC1 [Mapview hg19]  MPC1 [Mapview hg38]
OMIM614738   614741   
Gene and transcription
Genbank (Entrez)AF125101 AF151887 AF275811 AK310934 AK312201
RefSeq transcript (Entrez)NM_001270879 NM_016098
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MPC1
Cluster EST : UnigeneHs.172755 [ NCBI ]
CGAP (NCI)Hs.172755
Alternative Splicing GalleryENSG00000060762
Gene ExpressionMPC1 [ NCBI-GEO ]   MPC1 [ EBI - ARRAY_EXPRESS ]   MPC1 [ SEEK ]   MPC1 [ MEM ]
Gene Expression Viewer (FireBrowse)MPC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51660
GTEX Portal (Tissue expression)MPC1
Human Protein AtlasENSG00000060762-MPC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5U8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5U8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5U8
Splice isoforms : SwissVarQ9Y5U8
PhosPhoSitePlusQ9Y5U8
Domains : Interpro (EBI)MPC   
Domain families : Pfam (Sanger)MPC (PF03650)   
Domain families : Pfam (NCBI)pfam03650   
Conserved Domain (NCBI)MPC1
DMDM Disease mutations51660
Blocks (Seattle)MPC1
SuperfamilyQ9Y5U8
Human Protein Atlas [tissue]ENSG00000060762-MPC1 [tissue]
Peptide AtlasQ9Y5U8
HPRD07091
IPIIPI00412785   IPI00872782   IPI00943281   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5U8
IntAct (EBI)Q9Y5U8
FunCoupENSG00000060762
BioGRIDMPC1
STRING (EMBL)MPC1
ZODIACMPC1
Ontologies - Pathways
QuickGOQ9Y5U8
Ontology : AmiGOmolecular_function  cellular_component  mitochondrion  mitochondrial pyruvate transmembrane transport  biological_process  integral component of mitochondrial inner membrane  pyruvate transmembrane transporter activity  mitochondrial acetyl-CoA biosynthetic process from pyruvate  cellular response to leukemia inhibitory factor  
Ontology : EGO-EBImolecular_function  cellular_component  mitochondrion  mitochondrial pyruvate transmembrane transport  biological_process  integral component of mitochondrial inner membrane  pyruvate transmembrane transporter activity  mitochondrial acetyl-CoA biosynthetic process from pyruvate  cellular response to leukemia inhibitory factor  
NDEx NetworkMPC1
Atlas of Cancer Signalling NetworkMPC1
Wikipedia pathwaysMPC1
Orthology - Evolution
OrthoDB51660
GeneTree (enSembl)ENSG00000060762
Phylogenetic Trees/Animal Genes : TreeFamMPC1
HOVERGENQ9Y5U8
HOGENOMQ9Y5U8
Homologs : HomoloGeneMPC1
Homology/Alignments : Family Browser (UCSC)MPC1
Gene fusions - Rearrangements
Fusion : QuiverMPC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMPC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MPC1
dbVarMPC1
ClinVarMPC1
1000_GenomesMPC1 
Exome Variant ServerMPC1
ExAC (Exome Aggregation Consortium)ENSG00000060762
GNOMAD BrowserENSG00000060762
Varsome BrowserMPC1
Genetic variants : HAPMAP51660
Genomic Variants (DGV)MPC1 [DGVbeta]
DECIPHERMPC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMPC1 
Mutations
ICGC Data PortalMPC1 
TCGA Data PortalMPC1 
Broad Tumor PortalMPC1
OASIS PortalMPC1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMPC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MPC1
DgiDB (Drug Gene Interaction Database)MPC1
DoCM (Curated mutations)MPC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MPC1 (select a term)
intoGenMPC1
Cancer3DMPC1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614738    614741   
Orphanet23543   
DisGeNETMPC1
MedgenMPC1
Genetic Testing Registry MPC1
NextProtQ9Y5U8 [Medical]
TSGene51660
GENETestsMPC1
Target ValidationMPC1
Huge Navigator MPC1 [HugePedia]
snp3D : Map Gene to Disease51660
BioCentury BCIQMPC1
ClinGenMPC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51660
Chemical/Pharm GKB GenePA134940737
Clinical trialMPC1
Miscellaneous
canSAR (ICR)MPC1 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMPC1
EVEXMPC1
GoPubMedMPC1
iHOPMPC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:23:38 CET 2018

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