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MPC2 (mitochondrial pyruvate carrier 2)

Identity

Alias_namesBRP44
brain protein 44
Alias_symbol (synonym)DKFZP564B167
Other alias
HGNC (Hugo) MPC2
LocusID (NCBI) 25874
Atlas_Id 55100
Location 1q24.2  [Link to chromosome band 1q24]
Location_base_pair Starts at 167885913 and ends at 167906307 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
BLZF1 (1q24.2) / MPC2 (1q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MPC2   24515
Cards
Entrez_Gene (NCBI)MPC2  25874  mitochondrial pyruvate carrier 2
AliasesBRP44
GeneCards (Weizmann)MPC2
Ensembl hg19 (Hinxton)ENSG00000143158 [Gene_View]  chr1:167885913-167906307 [Contig_View]  MPC2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000143158 [Gene_View]  chr1:167885913-167906307 [Contig_View]  MPC2 [Vega]
ICGC DataPortalENSG00000143158
TCGA cBioPortalMPC2
AceView (NCBI)MPC2
Genatlas (Paris)MPC2
WikiGenes25874
SOURCE (Princeton)MPC2
Genetics Home Reference (NIH)MPC2
Genomic and cartography
GoldenPath hg19 (UCSC)MPC2  -     chr1:167885913-167906307 -  1q24.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MPC2  -     1q24.2   [Description]    (hg38-Dec_2013)
EnsemblMPC2 - 1q24.2 [CytoView hg19]  MPC2 - 1q24.2 [CytoView hg38]
Mapping of homologs : NCBIMPC2 [Mapview hg19]  MPC2 [Mapview hg38]
OMIM614737   
Gene and transcription
Genbank (Entrez)AK290126 AK307189 AK311913 AL035304 AL110297
RefSeq transcript (Entrez)NM_001143674 NM_015415
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)MPC2
Cluster EST : UnigeneHs.517768 [ NCBI ]
CGAP (NCI)Hs.517768
Alternative Splicing GalleryENSG00000143158
Gene ExpressionMPC2 [ NCBI-GEO ]   MPC2 [ EBI - ARRAY_EXPRESS ]   MPC2 [ SEEK ]   MPC2 [ MEM ]
Gene Expression Viewer (FireBrowse)MPC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25874
GTEX Portal (Tissue expression)MPC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95563   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95563  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95563
Splice isoforms : SwissVarO95563
PhosPhoSitePlusO95563
Domains : Interpro (EBI)MPC   
Domain families : Pfam (Sanger)MPC (PF03650)   
Domain families : Pfam (NCBI)pfam03650   
Conserved Domain (NCBI)MPC2
DMDM Disease mutations25874
Blocks (Seattle)MPC2
SuperfamilyO95563
Human Protein AtlasENSG00000143158
Peptide AtlasO95563
HPRD08525
IPIIPI00022832   IPI00640179   
Protein Interaction databases
DIP (DOE-UCLA)O95563
IntAct (EBI)O95563
FunCoupENSG00000143158
BioGRIDMPC2
STRING (EMBL)MPC2
ZODIACMPC2
Ontologies - Pathways
QuickGOO95563
Ontology : AmiGOnucleus  mitochondrion  mitochondrial inner membrane  integral component of membrane  positive regulation of insulin secretion involved in cellular response to glucose stimulus  pyruvate transmembrane transporter activity  mitochondrial acetyl-CoA biosynthetic process from pyruvate  mitochondrial pyruvate transmembrane transport  
Ontology : EGO-EBInucleus  mitochondrion  mitochondrial inner membrane  integral component of membrane  positive regulation of insulin secretion involved in cellular response to glucose stimulus  pyruvate transmembrane transporter activity  mitochondrial acetyl-CoA biosynthetic process from pyruvate  mitochondrial pyruvate transmembrane transport  
NDEx NetworkMPC2
Atlas of Cancer Signalling NetworkMPC2
Wikipedia pathwaysMPC2
Orthology - Evolution
OrthoDB25874
GeneTree (enSembl)ENSG00000143158
Phylogenetic Trees/Animal Genes : TreeFamMPC2
HOVERGENO95563
HOGENOMO95563
Homologs : HomoloGeneMPC2
Homology/Alignments : Family Browser (UCSC)MPC2
Gene fusions - Rearrangements
Fusion : MitelmanBLZF1/MPC2 [1q24.2/1q24.2]  [t(1;1)(q24;q24)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMPC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MPC2
dbVarMPC2
ClinVarMPC2
1000_GenomesMPC2 
Exome Variant ServerMPC2
ExAC (Exome Aggregation Consortium)MPC2 (select the gene name)
Genetic variants : HAPMAP25874
Genomic Variants (DGV)MPC2 [DGVbeta]
DECIPHER (Syndromes)1:167885913-167906307  ENSG00000143158
CONAN: Copy Number AnalysisMPC2 
Mutations
ICGC Data PortalMPC2 
TCGA Data PortalMPC2 
Broad Tumor PortalMPC2
OASIS PortalMPC2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMPC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MPC2
DgiDB (Drug Gene Interaction Database)MPC2
DoCM (Curated mutations)MPC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MPC2 (select a term)
intoGenMPC2
Cancer3DMPC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614737   
Orphanet
MedgenMPC2
Genetic Testing Registry MPC2
NextProtO95563 [Medical]
TSGene25874
GENETestsMPC2
Huge Navigator MPC2 [HugePedia]
snp3D : Map Gene to Disease25874
BioCentury BCIQMPC2
ClinGenMPC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25874
Chemical/Pharm GKB GenePA142672547
Clinical trialMPC2
Miscellaneous
canSAR (ICR)MPC2 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMPC2
EVEXMPC2
GoPubMedMPC2
iHOPMPC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:17:16 CET 2017

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