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MPG (N-methylpurine DNA glycosylase)

Identity

Other namesAAG
ADPG
APNG
CRA36.1
MDG
Mid1
PIG11
PIG16
anpg
HGNC (Hugo) MPG
LocusID (NCBI) 4350
Atlas_Id 41418
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 128169 and ends at 135850 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
EEA1 (12q22) / MPG (16p13.3)ENTPD6 (20p11.21) / MPG (16p13.3)MPG (16p13.3) / ENTPD6 (20p11.21)
MPG (16p13.3) / LOC100507412 (-)MPG (16p13.3) / MXI1 (10q25.2)MPG (16p13.3) / SNRNP25 (16p13.3)
EEA1 12q22 / MPG 16p13.3MPG 16p13.3 / SNRNP25 16p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MPG   7211
Cards
Entrez_Gene (NCBI)MPG  4350  N-methylpurine DNA glycosylase
AliasesAAG; ADPG; APNG; CRA36.1; 
MDG; Mid1; PIG11; PIG16; anpg
GeneCards (Weizmann)MPG
Ensembl hg19 (Hinxton)ENSG00000103152 [Gene_View]  chr16:128169-135850 [Contig_View]  MPG [Vega]
Ensembl hg38 (Hinxton)ENSG00000103152 [Gene_View]  chr16:128169-135850 [Contig_View]  MPG [Vega]
ICGC DataPortalENSG00000103152
TCGA cBioPortalMPG
AceView (NCBI)MPG
Genatlas (Paris)MPG
WikiGenes4350
SOURCE (Princeton)MPG
Genomic and cartography
GoldenPath hg19 (UCSC)MPG  -     chr16:128169-135850 +  16p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MPG  -     16p13.3   [Description]    (hg38-Dec_2013)
EnsemblMPG - 16p13.3 [CytoView hg19]  MPG - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBIMPG [Mapview hg19]  MPG [Mapview hg38]
OMIM156565   
Gene and transcription
Genbank (Entrez)AK308654 AL520052 AW083039 AY258284 BC014991
RefSeq transcript (Entrez)NM_001015052 NM_001015054 NM_002434
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010393 NW_004929400
Consensus coding sequences : CCDS (NCBI)MPG
Cluster EST : UnigeneHs.459596 [ NCBI ]
CGAP (NCI)Hs.459596
Alternative Splicing GalleryENSG00000103152
Gene ExpressionMPG [ NCBI-GEO ]   MPG [ EBI - ARRAY_EXPRESS ]   MPG [ SEEK ]   MPG [ MEM ]
Gene Expression Viewer (FireBrowse)MPG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4350
GTEX Portal (Tissue expression)MPG
Protein : pattern, domain, 3D structure
UniProt/SwissProtP29372 (Uniprot)
NextProtP29372  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP29372
Splice isoforms : SwissVarP29372 (Swissvar)
Catalytic activity : Enzyme3.2.2.21 [ Enzyme-Expasy ]   3.2.2.213.2.2.21 [ IntEnz-EBI ]   3.2.2.21 [ BRENDA ]   3.2.2.21 [ KEGG ]   
PhosPhoSitePlusP29372
Domains : Interpro (EBI)Formyl_transferase_C-like    PurDNA_glycsylse   
Domain families : Pfam (Sanger)Pur_DNA_glyco (PF02245)   
Domain families : Pfam (NCBI)pfam02245   
DMDM Disease mutations4350
Blocks (Seattle)MPG
PDB (SRS)1BNK    1EWN    1F4R    1F6O    3QI5    3UBY   
PDB (PDBSum)1BNK    1EWN    1F4R    1F6O    3QI5    3UBY   
PDB (IMB)1BNK    1EWN    1F4R    1F6O    3QI5    3UBY   
PDB (RSDB)1BNK    1EWN    1F4R    1F6O    3QI5    3UBY   
Structural Biology KnowledgeBase1BNK    1EWN    1F4R    1F6O    3QI5    3UBY   
SCOP (Structural Classification of Proteins)1BNK    1EWN    1F4R    1F6O    3QI5    3UBY   
CATH (Classification of proteins structures)1BNK    1EWN    1F4R    1F6O    3QI5    3UBY   
SuperfamilyP29372
Human Protein AtlasENSG00000103152
Peptide AtlasP29372
HPRD06766
IPIIPI00295497   IPI00218495   IPI00556107   IPI00748491   
Protein Interaction databases
DIP (DOE-UCLA)P29372
IntAct (EBI)P29372
FunCoupENSG00000103152
BioGRIDMPG
STRING (EMBL)MPG
ZODIACMPG
Ontologies - Pathways
QuickGOP29372
Ontology : AmiGOdamaged DNA binding  alkylbase DNA N-glycosylase activity  protein binding  nucleoplasm  base-excision repair  DNA dealkylation involved in DNA repair  DNA-3-methyladenine glycosylase activity  DNA N-glycosylase activity  mitochondrial nucleoid  DNA-7-methylguanine glycosylase activity  depurination  DNA-7-methyladenine glycosylase activity  DNA-3-methylguanine glycosylase activity  
Ontology : EGO-EBIdamaged DNA binding  alkylbase DNA N-glycosylase activity  protein binding  nucleoplasm  base-excision repair  DNA dealkylation involved in DNA repair  DNA-3-methyladenine glycosylase activity  DNA N-glycosylase activity  mitochondrial nucleoid  DNA-7-methylguanine glycosylase activity  depurination  DNA-7-methyladenine glycosylase activity  DNA-3-methylguanine glycosylase activity  
Pathways : KEGGBase excision repair   
NDEx NetworkMPG
Atlas of Cancer Signalling NetworkMPG
Wikipedia pathwaysMPG
Orthology - Evolution
OrthoDB4350
GeneTree (enSembl)ENSG00000103152
Phylogenetic Trees/Animal Genes : TreeFamMPG
Homologs : HomoloGeneMPG
Homology/Alignments : Family Browser (UCSC)MPG
Gene fusions - Rearrangements
Fusion: TCGAEEA1 12q22 MPG 16p13.3 OV
Fusion: TCGAMPG 16p13.3 SNRNP25 16p13.3 LUAD
Polymorphisms : SNP, variants
NCBI Variation ViewerMPG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MPG
dbVarMPG
ClinVarMPG
1000_GenomesMPG 
Exome Variant ServerMPG
ExAC (Exome Aggregation Consortium)MPG (select the gene name)
Genetic variants : HAPMAP4350
Genomic Variants (DGV)MPG [DGVbeta]
Mutations
ICGC Data PortalMPG 
TCGA Data PortalMPG 
Broad Tumor PortalMPG
OASIS PortalMPG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMPG 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MPG
DgiDB (Drug Gene Interaction Database)MPG
DoCM (Curated mutations)MPG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MPG (select a term)
intoGenMPG
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)16:128169-135850  ENSG00000103152
CONAN: Copy Number AnalysisMPG 
Mutations and Diseases : HGMDMPG
OMIM156565   
MedgenMPG
Genetic Testing Registry MPG
NextProtP29372 [Medical]
TSGene4350
GENETestsMPG
Huge Navigator MPG [HugePedia]
snp3D : Map Gene to Disease4350
BioCentury BCIQMPG
ClinGenMPG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4350
Chemical/Pharm GKB GenePA30917
Clinical trialMPG
Miscellaneous
canSAR (ICR)MPG (select the gene name)
Probes
Litterature
PubMed81 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMPG
EVEXMPG
GoPubMedMPG
iHOPMPG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 19 19:03:00 CEST 2016

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