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MPG (N-methylpurine-DNA glycosylase)

Identity

Other namesAAG
ADPG
APNG
CRA36.1
MDG
Mid1
PIG11
PIG16
anpg
HGNC (Hugo) MPG
LocusID (NCBI) 4350
Location 16p13.3
Location_base_pair Starts at 128169 and ends at 135850 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MPG   7211
Cards
Entrez_Gene (NCBI)MPG  4350  N-methylpurine-DNA glycosylase
GeneCards (Weizmann)MPG
Ensembl (Hinxton)ENSG00000103152 [Gene_View]  chr16:128169-135850 [Contig_View]  MPG [Vega]
ICGC DataPortalENSG00000103152
cBioPortalMPG
AceView (NCBI)MPG
Genatlas (Paris)MPG
WikiGenes4350
SOURCE (Princeton)NM_001015052 NM_001015054 NM_002434
Genomic and cartography
GoldenPath (UCSC)MPG  -  16p13.3   chr16:128169-135850 +  16p13.3   [Description]    (hg19-Feb_2009)
EnsemblMPG - 16p13.3 [CytoView]
Mapping of homologs : NCBIMPG [Mapview]
OMIM156565   
Gene and transcription
Genbank (Entrez)AK308654 AL520052 AW083039 AY258284 BC014991
RefSeq transcript (Entrez)NM_001015052 NM_001015054 NM_002434
RefSeq genomic (Entrez)AC_000148 NC_000016 NC_018927 NT_010393 NW_001838339 NW_004929400
Consensus coding sequences : CCDS (NCBI)MPG
Cluster EST : UnigeneHs.459596 [ NCBI ]
CGAP (NCI)Hs.459596
Alternative Splicing : Fast-db (Paris)GSHG0010786
Alternative Splicing GalleryENSG00000103152
Gene ExpressionMPG [ NCBI-GEO ]     MPG [ SEEK ]   MPG [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP29372 (Uniprot)
NextProtP29372  [Medical]
With graphics : InterProP29372
Splice isoforms : SwissVarP29372 (Swissvar)
Catalytic activity : Enzyme3.2.2.21 [ Enzyme-Expasy ]   3.2.2.213.2.2.21 [ IntEnz-EBI ]   3.2.2.21 [ BRENDA ]   3.2.2.21 [ KEGG ]   
Domains : Interpro (EBI)Formyl_transferase_C-like [organisation]   PurDNA_glycsylse [organisation]  
Related proteins : CluSTrP29372
Domain families : Pfam (Sanger)Pur_DNA_glyco (PF02245)   
Domain families : Pfam (NCBI)pfam02245   
DMDM Disease mutations4350
Blocks (Seattle)P29372
PDB (SRS)1BNK    1EWN    1F4R    1F6O    3QI5    3UBY   
PDB (PDBSum)1BNK    1EWN    1F4R    1F6O    3QI5    3UBY   
PDB (IMB)1BNK    1EWN    1F4R    1F6O    3QI5    3UBY   
PDB (RSDB)1BNK    1EWN    1F4R    1F6O    3QI5    3UBY   
Human Protein AtlasENSG00000103152 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP29372
HPRD06766
IPIIPI00295497   IPI00218495   IPI00556107   IPI00748491   
Protein Interaction databases
DIP (DOE-UCLA)P29372
IntAct (EBI)P29372
FunCoupENSG00000103152
BioGRIDMPG
InParanoidP29372
Interologous Interaction database P29372
IntegromeDBMPG
STRING (EMBL)MPG
Ontologies - Pathways
Ontology : AmiGOdamaged DNA binding  alkylbase DNA N-glycosylase activity  protein binding  nucleoplasm  DNA repair  base-excision repair  base-excision repair  base-excision repair, AP site formation  DNA dealkylation involved in DNA repair  DNA-3-methyladenine glycosylase activity  mitochondrial nucleoid  DNA-7-methylguanine glycosylase activity  depurination  DNA-7-methyladenine glycosylase activity  DNA-3-methylguanine glycosylase activity  
Ontology : EGO-EBIdamaged DNA binding  alkylbase DNA N-glycosylase activity  protein binding  nucleoplasm  DNA repair  base-excision repair  base-excision repair  base-excision repair, AP site formation  DNA dealkylation involved in DNA repair  DNA-3-methyladenine glycosylase activity  mitochondrial nucleoid  DNA-7-methylguanine glycosylase activity  depurination  DNA-7-methyladenine glycosylase activity  DNA-3-methylguanine glycosylase activity  
Pathways : KEGGBase excision repair   
Protein Interaction DatabaseMPG
Wikipedia pathwaysMPG
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)MPG
snp3D : Map Gene to Disease4350
SNP (GeneSNP Utah)MPG
SNP : HGBaseMPG
Genetic variants : HAPMAPMPG
Exome VariantMPG
1000_GenomesMPG 
ICGC programENSG00000103152 
Somatic Mutations in Cancer : COSMICMPG 
CONAN: Copy Number AnalysisMPG 
Mutations and Diseases : HGMDMPG
Genomic VariantsMPG  MPG [DGVbeta]
dbVarMPG
ClinVarMPG
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM156565   
MedgenMPG
GENETestsMPG
Disease Genetic AssociationMPG
Huge Navigator MPG [HugePedia]  MPG [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneMPG
Homology/Alignments : Family Browser (UCSC)MPG
Phylogenetic Trees/Animal Genes : TreeFamMPG
Chemical/Protein Interactions : CTD4350
Chemical/Pharm GKB GenePA30917
Clinical trialMPG
Cancer Resource (Charite)ENSG00000103152
Other databases
Probes
Litterature
PubMed73 Pubmed reference(s) in Entrez
CoreMineMPG
iHOPMPG
OncoSearchMPG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 14:06:29 CEST 2014

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