Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MPHOSPH10 (M-phase phosphoprotein 10)

Identity

Alias_namesM-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
Alias_symbol (synonym)MPP10
MPP10P
CT90
PPP1R106
Other alias
HGNC (Hugo) MPHOSPH10
LocusID (NCBI) 10199
Atlas_Id 70390
Location 2p13.3  [Link to chromosome band 2p13]
Location_base_pair Starts at 71130314 and ends at 71150102 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AES (19p13.3) / MPHOSPH10 (2p13.3)MPHOSPH10 (2p13.3) / AES (19p13.3)MPHOSPH10 (2p13.3) / GABRA2 (4p12)
MPHOSPH10 (2p13.3) / MPHOSPH10 (2p13.3)MPHOSPH10 (2p13.3) / SLC13A3 (20q13.12)SLC13A3 (20q13.12) / MPHOSPH10 (2p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MPHOSPH10   7213
Cards
Entrez_Gene (NCBI)MPHOSPH10  10199  M-phase phosphoprotein 10
AliasesCT90; MPP10; MPP10P; PPP1R106
GeneCards (Weizmann)MPHOSPH10
Ensembl hg19 (Hinxton)ENSG00000124383 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124383 [Gene_View]  chr2:71130314-71150102 [Contig_View]  MPHOSPH10 [Vega]
ICGC DataPortalENSG00000124383
TCGA cBioPortalMPHOSPH10
AceView (NCBI)MPHOSPH10
Genatlas (Paris)MPHOSPH10
WikiGenes10199
SOURCE (Princeton)MPHOSPH10
Genetics Home Reference (NIH)MPHOSPH10
Genomic and cartography
GoldenPath hg38 (UCSC)MPHOSPH10  -     chr2:71130314-71150102 +  2p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MPHOSPH10  -     2p13.3   [Description]    (hg19-Feb_2009)
EnsemblMPHOSPH10 - 2p13.3 [CytoView hg19]  MPHOSPH10 - 2p13.3 [CytoView hg38]
Mapping of homologs : NCBIMPHOSPH10 [Mapview hg19]  MPHOSPH10 [Mapview hg38]
OMIM605503   
Gene and transcription
Genbank (Entrez)AI056034 AK056862 AK310931 BC015158 BC041084
RefSeq transcript (Entrez)NM_005791
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MPHOSPH10
Cluster EST : UnigeneHs.656208 [ NCBI ]
CGAP (NCI)Hs.656208
Alternative Splicing GalleryENSG00000124383
Gene ExpressionMPHOSPH10 [ NCBI-GEO ]   MPHOSPH10 [ EBI - ARRAY_EXPRESS ]   MPHOSPH10 [ SEEK ]   MPHOSPH10 [ MEM ]
Gene Expression Viewer (FireBrowse)MPHOSPH10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10199
GTEX Portal (Tissue expression)MPHOSPH10
Human Protein AtlasENSG00000124383-MPHOSPH10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00566   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00566  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00566
Splice isoforms : SwissVarO00566
PhosPhoSitePlusO00566
Domains : Interpro (EBI)snoRNP_Mpp10   
Domain families : Pfam (Sanger)Mpp10 (PF04006)   
Domain families : Pfam (NCBI)pfam04006   
Conserved Domain (NCBI)MPHOSPH10
DMDM Disease mutations10199
Blocks (Seattle)MPHOSPH10
SuperfamilyO00566
Human Protein Atlas [tissue]ENSG00000124383-MPHOSPH10 [tissue]
Peptide AtlasO00566
HPRD10404
IPIIPI00012149   IPI00927397   
Protein Interaction databases
DIP (DOE-UCLA)O00566
IntAct (EBI)O00566
FunCoupENSG00000124383
BioGRIDMPHOSPH10
STRING (EMBL)MPHOSPH10
ZODIACMPHOSPH10
Ontologies - Pathways
QuickGOO00566
Ontology : AmiGORNA splicing, via transesterification reactions  RNA binding  protein binding  nucleoplasm  chromosome  nucleolus  small nucleolar ribonucleoprotein complex  rRNA processing  RNA processing  RNA splicing  negative regulation of phosphatase activity  maturation of SSU-rRNA  small-subunit processome  Mpp10 complex  
Ontology : EGO-EBIRNA splicing, via transesterification reactions  RNA binding  protein binding  nucleoplasm  chromosome  nucleolus  small nucleolar ribonucleoprotein complex  rRNA processing  RNA processing  RNA splicing  negative regulation of phosphatase activity  maturation of SSU-rRNA  small-subunit processome  Mpp10 complex  
Pathways : KEGGRibosome biogenesis in eukaryotes   
NDEx NetworkMPHOSPH10
Atlas of Cancer Signalling NetworkMPHOSPH10
Wikipedia pathwaysMPHOSPH10
Orthology - Evolution
OrthoDB10199
GeneTree (enSembl)ENSG00000124383
Phylogenetic Trees/Animal Genes : TreeFamMPHOSPH10
HOVERGENO00566
HOGENOMO00566
Homologs : HomoloGeneMPHOSPH10
Homology/Alignments : Family Browser (UCSC)MPHOSPH10
Gene fusions - Rearrangements
Fusion: Tumor Portal MPHOSPH10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMPHOSPH10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MPHOSPH10
dbVarMPHOSPH10
ClinVarMPHOSPH10
1000_GenomesMPHOSPH10 
Exome Variant ServerMPHOSPH10
ExAC (Exome Aggregation Consortium)ENSG00000124383
GNOMAD BrowserENSG00000124383
Genetic variants : HAPMAP10199
Genomic Variants (DGV)MPHOSPH10 [DGVbeta]
DECIPHERMPHOSPH10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMPHOSPH10 
Mutations
ICGC Data PortalMPHOSPH10 
TCGA Data PortalMPHOSPH10 
Broad Tumor PortalMPHOSPH10
OASIS PortalMPHOSPH10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMPHOSPH10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMPHOSPH10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MPHOSPH10
DgiDB (Drug Gene Interaction Database)MPHOSPH10
DoCM (Curated mutations)MPHOSPH10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MPHOSPH10 (select a term)
intoGenMPHOSPH10
Cancer3DMPHOSPH10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605503   
Orphanet
MedgenMPHOSPH10
Genetic Testing Registry MPHOSPH10
NextProtO00566 [Medical]
TSGene10199
GENETestsMPHOSPH10
Target ValidationMPHOSPH10
Huge Navigator MPHOSPH10 [HugePedia]
snp3D : Map Gene to Disease10199
BioCentury BCIQMPHOSPH10
ClinGenMPHOSPH10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10199
Chemical/Pharm GKB GenePA30919
Clinical trialMPHOSPH10
Miscellaneous
canSAR (ICR)MPHOSPH10 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMPHOSPH10
EVEXMPHOSPH10
GoPubMedMPHOSPH10
iHOPMPHOSPH10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:17:37 CET 2017

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