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MPLKIP (M-phase specific PLK1 interacting protein)

Identity

Other namesABHS
C7orf11
ORF20
TTD4
HGNC (Hugo) MPLKIP
LocusID (NCBI) 136647
Atlas_Id 45788
Location 7p14.1  [Link to chromosome band 7p14]
Location_base_pair Starts at 40172342 and ends at 40174251 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MPLKIP (7p14.1) / TRA2A (7p15.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Cancer prone implicated (Data extracted from papers in the Atlas) [ 1 ]
  Trichothiodystrophy (TTD)

External links

Nomenclature
HGNC (Hugo)MPLKIP   16002
Cards
Entrez_Gene (NCBI)MPLKIP  136647  M-phase specific PLK1 interacting protein
AliasesABHS; C7orf11; ORF20; TTD4
GeneCards (Weizmann)MPLKIP
Ensembl hg19 (Hinxton)ENSG00000168303 [Gene_View]  chr7:40172342-40174251 [Contig_View]  MPLKIP [Vega]
Ensembl hg38 (Hinxton)ENSG00000168303 [Gene_View]  chr7:40172342-40174251 [Contig_View]  MPLKIP [Vega]
ICGC DataPortalENSG00000168303
TCGA cBioPortalMPLKIP
AceView (NCBI)MPLKIP
Genatlas (Paris)MPLKIP
WikiGenes136647
SOURCE (Princeton)MPLKIP
Genomic and cartography
GoldenPath hg19 (UCSC)MPLKIP  -     chr7:40172342-40174251 -  7p14.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MPLKIP  -     7p14.1   [Description]    (hg38-Dec_2013)
EnsemblMPLKIP - 7p14.1 [CytoView hg19]  MPLKIP - 7p14.1 [CytoView hg38]
Mapping of homologs : NCBIMPLKIP [Mapview hg19]  MPLKIP [Mapview hg38]
OMIM234050   609188   
Gene and transcription
Genbank (Entrez)AK290098 BC026265 BG501110 HQ447766
RefSeq transcript (Entrez)NM_138701
RefSeq genomic (Entrez)NC_000007 NC_018918 NG_016989 NG_023422 NT_007819 NW_004929329
Consensus coding sequences : CCDS (NCBI)MPLKIP
Cluster EST : UnigeneHs.654989 [ NCBI ]
CGAP (NCI)Hs.654989
Alternative Splicing GalleryENSG00000168303
Gene ExpressionMPLKIP [ NCBI-GEO ]   MPLKIP [ EBI - ARRAY_EXPRESS ]   MPLKIP [ SEEK ]   MPLKIP [ MEM ]
Gene Expression Viewer (FireBrowse)MPLKIP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)136647
GTEX Portal (Tissue expression)MPLKIP
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TAP9 (Uniprot)
NextProtQ8TAP9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TAP9
Splice isoforms : SwissVarQ8TAP9 (Swissvar)
PhosPhoSitePlusQ8TAP9
Domains : Interpro (EBI)MPLKIP-like    MPLKIP-like_vertebrate   
Domain families : Pfam (Sanger)MPLKIP (PF15502)   
Domain families : Pfam (NCBI)pfam15502   
DMDM Disease mutations136647
Blocks (Seattle)MPLKIP
SuperfamilyQ8TAP9
Human Protein AtlasENSG00000168303
Peptide AtlasQ8TAP9
HPRD12907
IPIIPI00152083   
Protein Interaction databases
DIP (DOE-UCLA)Q8TAP9
IntAct (EBI)Q8TAP9
FunCoupENSG00000168303
BioGRIDMPLKIP
STRING (EMBL)MPLKIP
ZODIACMPLKIP
Ontologies - Pathways
QuickGOQ8TAP9
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  cytoplasm  Golgi apparatus  centrosome  mitotic nuclear division  midbody  cell division  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  cytoplasm  Golgi apparatus  centrosome  mitotic nuclear division  midbody  cell division  
NDEx Network
Atlas of Cancer Signalling NetworkMPLKIP
Wikipedia pathwaysMPLKIP
Orthology - Evolution
OrthoDB136647
GeneTree (enSembl)ENSG00000168303
Phylogenetic Trees/Animal Genes : TreeFamMPLKIP
Homologs : HomoloGeneMPLKIP
Homology/Alignments : Family Browser (UCSC)MPLKIP
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerMPLKIP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MPLKIP
dbVarMPLKIP
ClinVarMPLKIP
1000_GenomesMPLKIP 
Exome Variant ServerMPLKIP
ExAC (Exome Aggregation Consortium)MPLKIP (select the gene name)
Genetic variants : HAPMAP136647
Genomic Variants (DGV)MPLKIP [DGVbeta]
Mutations
ICGC Data PortalMPLKIP 
TCGA Data PortalMPLKIP 
Broad Tumor PortalMPLKIP
OASIS PortalMPLKIP [ Somatic mutations - Copy number]
BioMutasearch MPLKIP
DgiDB (Drug Gene Interaction Database)MPLKIP
DoCM (Curated mutations)MPLKIP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MPLKIP (select a term)
intoGenMPLKIP
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)7:40172342-40174251  ENSG00000168303
CONAN: Copy Number AnalysisMPLKIP 
Mutations and Diseases : HGMDMPLKIP
OMIM234050    609188   
MedgenMPLKIP
Genetic Testing Registry MPLKIP
NextProtQ8TAP9 [Medical]
TSGene136647
GENETestsMPLKIP
Huge Navigator MPLKIP [HugePedia]
snp3D : Map Gene to Disease136647
BioCentury BCIQMPLKIP
ClinGenMPLKIP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD136647
Chemical/Pharm GKB GenePA25943
Clinical trialMPLKIP
Miscellaneous
canSAR (ICR)MPLKIP (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMPLKIP
EVEXMPLKIP
GoPubMedMPLKIP
iHOPMPLKIP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Aug 9 19:31:21 CEST 2016

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