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MPP4 (membrane palmitoylated protein 4)

Identity

Alias_namesDLG6
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
membrane protein, palmitoylated 4
Other aliasALS2CR5
HGNC (Hugo) MPP4
LocusID (NCBI) 58538
Atlas_Id 70393
Location 2q33.1  [Link to chromosome band 2q33]
Location_base_pair Starts at 201644874 and ends at 201698694 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MPP4   13680
Cards
Entrez_Gene (NCBI)MPP4  58538  membrane palmitoylated protein 4
AliasesALS2CR5; DLG6
GeneCards (Weizmann)MPP4
Ensembl hg19 (Hinxton)ENSG00000082126 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000082126 [Gene_View]  ENSG00000082126 [Sequence]  chr2:201644874-201698694 [Contig_View]  MPP4 [Vega]
ICGC DataPortalENSG00000082126
TCGA cBioPortalMPP4
AceView (NCBI)MPP4
Genatlas (Paris)MPP4
WikiGenes58538
SOURCE (Princeton)MPP4
Genetics Home Reference (NIH)MPP4
Genomic and cartography
GoldenPath hg38 (UCSC)MPP4  -     chr2:201644874-201698694 -  2q33.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MPP4  -     2q33.1   [Description]    (hg19-Feb_2009)
EnsemblMPP4 - 2q33.1 [CytoView hg19]  MPP4 - 2q33.1 [CytoView hg38]
Mapping of homologs : NCBIMPP4 [Mapview hg19]  MPP4 [Mapview hg38]
OMIM606575   
Gene and transcription
Genbank (Entrez)AB053302 AB053303 AB053304 AF316032 AK131208
RefSeq transcript (Entrez)NM_033066
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MPP4
Cluster EST : UnigeneHs.63085 [ NCBI ]
CGAP (NCI)Hs.63085
Alternative Splicing GalleryENSG00000082126
Gene ExpressionMPP4 [ NCBI-GEO ]   MPP4 [ EBI - ARRAY_EXPRESS ]   MPP4 [ SEEK ]   MPP4 [ MEM ]
Gene Expression Viewer (FireBrowse)MPP4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)58538
GTEX Portal (Tissue expression)MPP4
Human Protein AtlasENSG00000082126-MPP4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96JB8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96JB8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96JB8
Splice isoforms : SwissVarQ96JB8
PhosPhoSitePlusQ96JB8
Domaine pattern : Prosite (Expaxy)GUANYLATE_KINASE_1 (PS00856)    GUANYLATE_KINASE_2 (PS50052)    L27 (PS51022)    PDZ (PS50106)    SH3 (PS50002)   
Domains : Interpro (EBI)GK/Ca_channel_bsu    Guanylate_kin-like_dom    Guanylate_kinase_CS    L27_C    L27_dom    P-loop_NTPase    PDZ    SH3_domain   
Domain families : Pfam (Sanger)Guanylate_kin (PF00625)    L27 (PF02828)    PDZ (PF00595)   
Domain families : Pfam (NCBI)pfam00625    pfam02828    pfam00595   
Domain families : Smart (EMBL)GuKc (SM00072)  L27 (SM00569)  PDZ (SM00228)  SH3 (SM00326)  
Conserved Domain (NCBI)MPP4
DMDM Disease mutations58538
Blocks (Seattle)MPP4
SuperfamilyQ96JB8
Human Protein Atlas [tissue]ENSG00000082126-MPP4 [tissue]
Peptide AtlasQ96JB8
HPRD07360
IPIIPI00157237   IPI00220204   IPI00604511   IPI01013504   IPI00744582   IPI01013472   IPI00917842   IPI00916556   IPI00220205   IPI00925382   IPI00926329   
Protein Interaction databases
DIP (DOE-UCLA)Q96JB8
IntAct (EBI)Q96JB8
FunCoupENSG00000082126
BioGRIDMPP4
STRING (EMBL)MPP4
ZODIACMPP4
Ontologies - Pathways
QuickGOQ96JB8
Ontology : AmiGOcytoplasm  
Ontology : EGO-EBIcytoplasm  
NDEx NetworkMPP4
Atlas of Cancer Signalling NetworkMPP4
Wikipedia pathwaysMPP4
Orthology - Evolution
OrthoDB58538
GeneTree (enSembl)ENSG00000082126
Phylogenetic Trees/Animal Genes : TreeFamMPP4
HOVERGENQ96JB8
HOGENOMQ96JB8
Homologs : HomoloGeneMPP4
Homology/Alignments : Family Browser (UCSC)MPP4
Gene fusions - Rearrangements
Fusion : QuiverMPP4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMPP4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MPP4
dbVarMPP4
ClinVarMPP4
1000_GenomesMPP4 
Exome Variant ServerMPP4
ExAC (Exome Aggregation Consortium)ENSG00000082126
GNOMAD BrowserENSG00000082126
Varsome BrowserMPP4
Genetic variants : HAPMAP58538
Genomic Variants (DGV)MPP4 [DGVbeta]
DECIPHERMPP4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMPP4 
Mutations
ICGC Data PortalMPP4 
TCGA Data PortalMPP4 
Broad Tumor PortalMPP4
OASIS PortalMPP4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMPP4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMPP4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MPP4
DgiDB (Drug Gene Interaction Database)MPP4
DoCM (Curated mutations)MPP4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MPP4 (select a term)
intoGenMPP4
Cancer3DMPP4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606575   
Orphanet
DisGeNETMPP4
MedgenMPP4
Genetic Testing Registry MPP4
NextProtQ96JB8 [Medical]
TSGene58538
GENETestsMPP4
Target ValidationMPP4
Huge Navigator MPP4 [HugePedia]
snp3D : Map Gene to Disease58538
BioCentury BCIQMPP4
ClinGenMPP4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD58538
Chemical/Pharm GKB GenePA30927
Clinical trialMPP4
Miscellaneous
canSAR (ICR)MPP4 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMPP4
EVEXMPP4
GoPubMedMPP4
iHOPMPP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:18:17 CEST 2018
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