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MPP6 (membrane palmitoylated protein 6)

Identity

Alias_namesmembrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
membrane protein, palmitoylated 6
Alias_symbol (synonym)PALS2
VAM-1
p55T
Other aliasVAM1
HGNC (Hugo) MPP6
LocusID (NCBI) 51678
Atlas_Id 41424
Location 7p15.3  [Link to chromosome band 7p15]
Location_base_pair Starts at 24612965 and ends at 24733322 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DYNC1H1 (14q32.31) / MPP6 (7p15.3)MPP6 (7p15.3) / MPP6 (7p15.3)MPP6 (7p15.3) / OSBPL3 (7p15.3)
MPP6 7p15.3 / OSBPL3 7p15.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MPP6   18167
Cards
Entrez_Gene (NCBI)MPP6  51678  membrane palmitoylated protein 6
AliasesPALS2; VAM-1; VAM1; p55T
GeneCards (Weizmann)MPP6
Ensembl hg19 (Hinxton)ENSG00000105926 [Gene_View]  chr7:24612965-24733322 [Contig_View]  MPP6 [Vega]
Ensembl hg38 (Hinxton)ENSG00000105926 [Gene_View]  chr7:24612965-24733322 [Contig_View]  MPP6 [Vega]
ICGC DataPortalENSG00000105926
TCGA cBioPortalMPP6
AceView (NCBI)MPP6
Genatlas (Paris)MPP6
WikiGenes51678
SOURCE (Princeton)MPP6
Genetics Home Reference (NIH)MPP6
Genomic and cartography
GoldenPath hg19 (UCSC)MPP6  -     chr7:24612965-24733322 +  7p15.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MPP6  -     7p15.3   [Description]    (hg38-Dec_2013)
EnsemblMPP6 - 7p15.3 [CytoView hg19]  MPP6 - 7p15.3 [CytoView hg38]
Mapping of homologs : NCBIMPP6 [Mapview hg19]  MPP6 [Mapview hg38]
OMIM606959   
Gene and transcription
Genbank (Entrez)AF162130 AL136836 BC012034 BC013077 BC023638
RefSeq transcript (Entrez)NM_001303037 NM_016447
RefSeq genomic (Entrez)NC_000007 NC_018918 NT_007819 NW_004929329
Consensus coding sequences : CCDS (NCBI)MPP6
Cluster EST : UnigeneHs.594275 [ NCBI ]
CGAP (NCI)Hs.594275
Alternative Splicing GalleryENSG00000105926
Gene ExpressionMPP6 [ NCBI-GEO ]   MPP6 [ EBI - ARRAY_EXPRESS ]   MPP6 [ SEEK ]   MPP6 [ MEM ]
Gene Expression Viewer (FireBrowse)MPP6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51678
GTEX Portal (Tissue expression)MPP6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZW5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZW5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZW5
Splice isoforms : SwissVarQ9NZW5
PhosPhoSitePlusQ9NZW5
Domaine pattern : Prosite (Expaxy)GUANYLATE_KINASE_1 (PS00856)    GUANYLATE_KINASE_2 (PS50052)    L27 (PS51022)    PDZ (PS50106)    SH3 (PS50002)   
Domains : Interpro (EBI)GK/Ca_channel_bsu    Guanylate_kin-like_dom    Guanylate_kinase_CS    L27_C    L27_dom    P-loop_NTPase    PDZ    SH3_2    SH3_domain   
Domain families : Pfam (Sanger)Guanylate_kin (PF00625)    L27 (PF02828)    PDZ (PF00595)    SH3_2 (PF07653)   
Domain families : Pfam (NCBI)pfam00625    pfam02828    pfam00595    pfam07653   
Domain families : Smart (EMBL)GuKc (SM00072)  L27 (SM00569)  PDZ (SM00228)  SH3 (SM00326)  
Conserved Domain (NCBI)MPP6
DMDM Disease mutations51678
Blocks (Seattle)MPP6
SuperfamilyQ9NZW5
Human Protein AtlasENSG00000105926
Peptide AtlasQ9NZW5
HPRD09509
IPIIPI00303280   IPI00917964   IPI00916028   IPI00915876   IPI00917879   IPI00916455   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZW5
IntAct (EBI)Q9NZW5
FunCoupENSG00000105926
BioGRIDMPP6
STRING (EMBL)MPP6
ZODIACMPP6
Ontologies - Pathways
QuickGOQ9NZW5
Ontology : AmiGOprotein binding  plasma membrane  protein complex assembly  membrane  PDZ domain binding  extracellular exosome  
Ontology : EGO-EBIprotein binding  plasma membrane  protein complex assembly  membrane  PDZ domain binding  extracellular exosome  
NDEx NetworkMPP6
Atlas of Cancer Signalling NetworkMPP6
Wikipedia pathwaysMPP6
Orthology - Evolution
OrthoDB51678
GeneTree (enSembl)ENSG00000105926
Phylogenetic Trees/Animal Genes : TreeFamMPP6
HOVERGENQ9NZW5
HOGENOMQ9NZW5
Homologs : HomoloGeneMPP6
Homology/Alignments : Family Browser (UCSC)MPP6
Gene fusions - Rearrangements
Fusion : MitelmanMPP6/OSBPL3 [7p15.3/7p15.3]  
Fusion: TCGAMPP6 7p15.3 OSBPL3 7p15.3 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMPP6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MPP6
dbVarMPP6
ClinVarMPP6
1000_GenomesMPP6 
Exome Variant ServerMPP6
ExAC (Exome Aggregation Consortium)MPP6 (select the gene name)
Genetic variants : HAPMAP51678
Genomic Variants (DGV)MPP6 [DGVbeta]
DECIPHER (Syndromes)7:24612965-24733322  ENSG00000105926
CONAN: Copy Number AnalysisMPP6 
Mutations
ICGC Data PortalMPP6 
TCGA Data PortalMPP6 
Broad Tumor PortalMPP6
OASIS PortalMPP6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMPP6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMPP6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MPP6
DgiDB (Drug Gene Interaction Database)MPP6
DoCM (Curated mutations)MPP6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MPP6 (select a term)
intoGenMPP6
Cancer3DMPP6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606959   
Orphanet
MedgenMPP6
Genetic Testing Registry MPP6
NextProtQ9NZW5 [Medical]
TSGene51678
GENETestsMPP6
Huge Navigator MPP6 [HugePedia]
snp3D : Map Gene to Disease51678
BioCentury BCIQMPP6
ClinGenMPP6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51678
Chemical/Pharm GKB GenePA38511
Clinical trialMPP6
Miscellaneous
canSAR (ICR)MPP6 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMPP6
EVEXMPP6
GoPubMedMPP6
iHOPMPP6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:10:59 CEST 2017

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