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MPPE1 (metallophosphoesterase 1)

Identity

Other aliasPGAP5
HGNC (Hugo) MPPE1
LocusID (NCBI) 65258
Atlas_Id 70395
Location 18p11.21  [Link to chromosome band 18p11]
Location_base_pair Starts at 11883471 and ends at 11908797 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MPPE1 (18p11.21) / FMO5 (1q21.1)PPM1G (2p23.3) / MPPE1 (18p11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MPPE1   15988
Cards
Entrez_Gene (NCBI)MPPE1  65258  metallophosphoesterase 1
AliasesPGAP5
GeneCards (Weizmann)MPPE1
Ensembl hg19 (Hinxton)ENSG00000154889 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000154889 [Gene_View]  chr18:11883471-11908797 [Contig_View]  MPPE1 [Vega]
ICGC DataPortalENSG00000154889
TCGA cBioPortalMPPE1
AceView (NCBI)MPPE1
Genatlas (Paris)MPPE1
WikiGenes65258
SOURCE (Princeton)MPPE1
Genetics Home Reference (NIH)MPPE1
Genomic and cartography
GoldenPath hg38 (UCSC)MPPE1  -     chr18:11883471-11908797 -  18p11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MPPE1  -     18p11.21   [Description]    (hg19-Feb_2009)
EnsemblMPPE1 - 18p11.21 [CytoView hg19]  MPPE1 - 18p11.21 [CytoView hg38]
Mapping of homologs : NCBIMPPE1 [Mapview hg19]  MPPE1 [Mapview hg38]
OMIM611900   
Gene and transcription
Genbank (Entrez)AF289560 AF363484 AK021647 AK023052 AK054639
RefSeq transcript (Entrez)NM_001242904 NM_001319154 NM_001330563 NM_023075 NM_138608
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MPPE1
Cluster EST : UnigeneHs.734268 [ NCBI ]
CGAP (NCI)Hs.734268
Alternative Splicing GalleryENSG00000154889
Gene ExpressionMPPE1 [ NCBI-GEO ]   MPPE1 [ EBI - ARRAY_EXPRESS ]   MPPE1 [ SEEK ]   MPPE1 [ MEM ]
Gene Expression Viewer (FireBrowse)MPPE1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)65258
GTEX Portal (Tissue expression)MPPE1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ53F39   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ53F39  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ53F39
Splice isoforms : SwissVarQ53F39
Catalytic activity : Enzyme3.1.-.- [ Enzyme-Expasy ]   3.1.-.-3.1.-.- [ IntEnz-EBI ]   3.1.-.- [ BRENDA ]   3.1.-.- [ KEGG ]   
PhosPhoSitePlusQ53F39
Domains : Interpro (EBI)Calcineurin-like_PHP_ApaH    Metallo-depent_PP-like    PGAP5/Cdc1/Ted1   
Domain families : Pfam (Sanger)Metallophos (PF00149)   
Domain families : Pfam (NCBI)pfam00149   
Conserved Domain (NCBI)MPPE1
DMDM Disease mutations65258
Blocks (Seattle)MPPE1
SuperfamilyQ53F39
Human Protein AtlasENSG00000154889
Peptide AtlasQ53F39
HPRD14734
IPIIPI00914979   IPI00977155   IPI00042492   IPI00878898   IPI00789564   
Protein Interaction databases
DIP (DOE-UCLA)Q53F39
IntAct (EBI)Q53F39
FunCoupENSG00000154889
BioGRIDMPPE1
STRING (EMBL)MPPE1
ZODIACMPPE1
Ontologies - Pathways
QuickGOQ53F39
Ontology : AmiGOprotein binding  nucleoplasm  endoplasmic reticulum  endoplasmic reticulum-Golgi intermediate compartment  Golgi apparatus  cis-Golgi network  GPI anchor biosynthetic process  GPI anchor biosynthetic process  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  phosphoric diester hydrolase activity  integral component of membrane  manganese ion binding  endoplasmic reticulum-Golgi intermediate compartment membrane  GPI anchor binding  endoplasmic reticulum exit site  
Ontology : EGO-EBIprotein binding  nucleoplasm  endoplasmic reticulum  endoplasmic reticulum-Golgi intermediate compartment  Golgi apparatus  cis-Golgi network  GPI anchor biosynthetic process  GPI anchor biosynthetic process  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  phosphoric diester hydrolase activity  integral component of membrane  manganese ion binding  endoplasmic reticulum-Golgi intermediate compartment membrane  GPI anchor binding  endoplasmic reticulum exit site  
NDEx NetworkMPPE1
Atlas of Cancer Signalling NetworkMPPE1
Wikipedia pathwaysMPPE1
Orthology - Evolution
OrthoDB65258
GeneTree (enSembl)ENSG00000154889
Phylogenetic Trees/Animal Genes : TreeFamMPPE1
HOVERGENQ53F39
HOGENOMQ53F39
Homologs : HomoloGeneMPPE1
Homology/Alignments : Family Browser (UCSC)MPPE1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMPPE1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MPPE1
dbVarMPPE1
ClinVarMPPE1
1000_GenomesMPPE1 
Exome Variant ServerMPPE1
ExAC (Exome Aggregation Consortium)MPPE1 (select the gene name)
Genetic variants : HAPMAP65258
Genomic Variants (DGV)MPPE1 [DGVbeta]
DECIPHERMPPE1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMPPE1 
Mutations
ICGC Data PortalMPPE1 
TCGA Data PortalMPPE1 
Broad Tumor PortalMPPE1
OASIS PortalMPPE1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMPPE1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMPPE1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MPPE1
DgiDB (Drug Gene Interaction Database)MPPE1
DoCM (Curated mutations)MPPE1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MPPE1 (select a term)
intoGenMPPE1
Cancer3DMPPE1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611900   
Orphanet
MedgenMPPE1
Genetic Testing Registry MPPE1
NextProtQ53F39 [Medical]
TSGene65258
GENETestsMPPE1
Target ValidationMPPE1
Huge Navigator MPPE1 [HugePedia]
snp3D : Map Gene to Disease65258
BioCentury BCIQMPPE1
ClinGenMPPE1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD65258
Chemical/Pharm GKB GenePA134913534
Clinical trialMPPE1
Miscellaneous
canSAR (ICR)MPPE1 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMPPE1
EVEXMPPE1
GoPubMedMPPE1
iHOPMPPE1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:31:18 CEST 2017

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