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MPRIP (myosin phosphatase Rho interacting protein)

Identity

Alias_symbol (synonym)RHOIP3
M-RIP
p116Rip
Other aliasMRIP
RIP3
HGNC (Hugo) MPRIP
LocusID (NCBI) 23164
Atlas_Id 50434
Location 17p11.2  [Link to chromosome band 17p11]
Location_base_pair Starts at 16946074 and ends at 17095962 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MPRIP (17p11.2) / FTL (19q13.33)MPRIP (17p11.2) / NTRK1 (1q23.1)MPRIP (17p11.2) / PDGFRB (5q32)
MPRIP (17p11.2) / RAF1 (3p25.2)MPRIP (17p11.2) / TP53 (17p13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)MPRIP   30321
Cards
Entrez_Gene (NCBI)MPRIP  23164  myosin phosphatase Rho interacting protein
AliasesM-RIP; MRIP; RHOIP3; RIP3; 
p116Rip
GeneCards (Weizmann)MPRIP
Ensembl hg19 (Hinxton)ENSG00000133030 [Gene_View]  chr17:16946074-17095962 [Contig_View]  MPRIP [Vega]
Ensembl hg38 (Hinxton)ENSG00000133030 [Gene_View]  chr17:16946074-17095962 [Contig_View]  MPRIP [Vega]
ICGC DataPortalENSG00000133030
TCGA cBioPortalMPRIP
AceView (NCBI)MPRIP
Genatlas (Paris)MPRIP
WikiGenes23164
SOURCE (Princeton)MPRIP
Genetics Home Reference (NIH)MPRIP
Genomic and cartography
GoldenPath hg19 (UCSC)MPRIP  -     chr17:16946074-17095962 +  17p11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MPRIP  -     17p11.2   [Description]    (hg38-Dec_2013)
EnsemblMPRIP - 17p11.2 [CytoView hg19]  MPRIP - 17p11.2 [CytoView hg38]
Mapping of homologs : NCBIMPRIP [Mapview hg19]  MPRIP [Mapview hg38]
OMIM612935   
Gene and transcription
Genbank (Entrez)AB020671 AB098507 AB189741 AB362572 AB362573
RefSeq transcript (Entrez)NM_015134 NM_201274
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010718 NW_004929405
Consensus coding sequences : CCDS (NCBI)MPRIP
Cluster EST : UnigeneHs.462341 [ NCBI ]
CGAP (NCI)Hs.462341
Alternative Splicing GalleryENSG00000133030
Gene ExpressionMPRIP [ NCBI-GEO ]   MPRIP [ EBI - ARRAY_EXPRESS ]   MPRIP [ SEEK ]   MPRIP [ MEM ]
Gene Expression Viewer (FireBrowse)MPRIP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23164
GTEX Portal (Tissue expression)MPRIP
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6WCQ1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6WCQ1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6WCQ1
Splice isoforms : SwissVarQ6WCQ1
PhosPhoSitePlusQ6WCQ1
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)PH (PF00169)   
Domain families : Pfam (NCBI)pfam00169   
Domain families : Smart (EMBL)PH (SM00233)  
Conserved Domain (NCBI)MPRIP
DMDM Disease mutations23164
Blocks (Seattle)MPRIP
SuperfamilyQ6WCQ1
Human Protein AtlasENSG00000133030
Peptide AtlasQ6WCQ1
HPRD17591
IPIIPI00305344   IPI00295457   IPI00166518   IPI00874193   IPI00797766   IPI00788613   IPI00789235   IPI00790581   
Protein Interaction databases
DIP (DOE-UCLA)Q6WCQ1
IntAct (EBI)Q6WCQ1
FunCoupENSG00000133030
BioGRIDMPRIP
STRING (EMBL)MPRIP
ZODIACMPRIP
Ontologies - Pathways
QuickGOQ6WCQ1
Ontology : AmiGOactin binding  protein binding  cytoplasm  focal adhesion  actin cytoskeleton  
Ontology : EGO-EBIactin binding  protein binding  cytoplasm  focal adhesion  actin cytoskeleton  
NDEx NetworkMPRIP
Atlas of Cancer Signalling NetworkMPRIP
Wikipedia pathwaysMPRIP
Orthology - Evolution
OrthoDB23164
GeneTree (enSembl)ENSG00000133030
Phylogenetic Trees/Animal Genes : TreeFamMPRIP
HOVERGENQ6WCQ1
HOGENOMQ6WCQ1
Homologs : HomoloGeneMPRIP
Homology/Alignments : Family Browser (UCSC)MPRIP
Gene fusions - Rearrangements
Fusion : MitelmanMPRIP/TP53 [17p11.2/17p13.1]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMPRIP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MPRIP
dbVarMPRIP
ClinVarMPRIP
1000_GenomesMPRIP 
Exome Variant ServerMPRIP
ExAC (Exome Aggregation Consortium)MPRIP (select the gene name)
Genetic variants : HAPMAP23164
Genomic Variants (DGV)MPRIP [DGVbeta]
DECIPHER (Syndromes)17:16946074-17095962  ENSG00000133030
CONAN: Copy Number AnalysisMPRIP 
Mutations
ICGC Data PortalMPRIP 
TCGA Data PortalMPRIP 
Broad Tumor PortalMPRIP
OASIS PortalMPRIP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMPRIP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMPRIP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MPRIP
DgiDB (Drug Gene Interaction Database)MPRIP
DoCM (Curated mutations)MPRIP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MPRIP (select a term)
intoGenMPRIP
Cancer3DMPRIP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612935   
Orphanet
MedgenMPRIP
Genetic Testing Registry MPRIP
NextProtQ6WCQ1 [Medical]
TSGene23164
GENETestsMPRIP
Huge Navigator MPRIP [HugePedia]
snp3D : Map Gene to Disease23164
BioCentury BCIQMPRIP
ClinGenMPRIP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23164
Chemical/Pharm GKB GenePA162396092
Clinical trialMPRIP
Miscellaneous
canSAR (ICR)MPRIP (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMPRIP
EVEXMPRIP
GoPubMedMPRIP
iHOPMPRIP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:11:00 CEST 2017

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