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MPST (mercaptopyruvate sulfurtransferase)

Identity

Alias (NCBI)MST
TST2
TUM1
HGNC (Hugo) MPST
HGNC Alias symbMST
TST2
TUM1
HGNC Alias namehuman liver rhodanese
 tRNA thiouridin modification protein 1
LocusID (NCBI) 4357
Atlas_Id 70397
Location 22q12.3  [Link to chromosome band 22q12]
Location_base_pair Starts at 37019820 and ends at 37029814 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MPST (22q12.3) / WAS (Xp11.23)VAT1 (17q21.31) / MPST (22q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MPST   7223
Cards
Entrez_Gene (NCBI)MPST    mercaptopyruvate sulfurtransferase
AliasesMST; TST2; TUM1
GeneCards (Weizmann)MPST
Ensembl hg19 (Hinxton)ENSG00000128309 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000128309 [Gene_View]  ENSG00000128309 [Sequence]  chr22:37019820-37029814 [Contig_View]  MPST [Vega]
ICGC DataPortalENSG00000128309
TCGA cBioPortalMPST
AceView (NCBI)MPST
Genatlas (Paris)MPST
SOURCE (Princeton)MPST
Genetics Home Reference (NIH)MPST
Genomic and cartography
GoldenPath hg38 (UCSC)MPST  -     chr22:37019820-37029814 +  22q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MPST  -     22q12.3   [Description]    (hg19-Feb_2009)
GoldenPathMPST - 22q12.3 [CytoView hg19]  MPST - 22q12.3 [CytoView hg38]
ImmunoBaseENSG00000128309
Genome Data Viewer NCBIMPST [Mapview hg19]  
OMIM602496   
Gene and transcription
Genbank (Entrez)AB208824 AK055733 AW778940 BC003508 BC009450
RefSeq transcript (Entrez)NM_001013436 NM_001013440 NM_001130517 NM_001369904 NM_001369905 NM_021126
Consensus coding sequences : CCDS (NCBI)MPST
Gene ExpressionMPST [ NCBI-GEO ]   MPST [ EBI - ARRAY_EXPRESS ]   MPST [ SEEK ]   MPST [ MEM ]
Gene Expression Viewer (FireBrowse)MPST [ Firebrowse - Broad ]
GenevisibleExpression of MPST in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4357
GTEX Portal (Tissue expression)MPST
Human Protein AtlasENSG00000128309-MPST [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP25325   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP25325  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP25325
PhosPhoSitePlusP25325
Domaine pattern : Prosite (Expaxy)RHODANESE_1 (PS00380)    RHODANESE_2 (PS00683)    RHODANESE_3 (PS50206)   
Domains : Interpro (EBI)Rhodanese-like_dom    Rhodanese-like_dom_sf    Thiosulphate_STrfase_CS   
Domain families : Pfam (Sanger)Rhodanese (PF00581)   
Domain families : Pfam (NCBI)pfam00581   
Domain families : Smart (EMBL)RHOD (SM00450)  
Conserved Domain (NCBI)MPST
PDB (RSDB)3OLH    4JGT   
PDB Europe3OLH    4JGT   
PDB (PDBSum)3OLH    4JGT   
PDB (IMB)3OLH    4JGT   
Structural Biology KnowledgeBase3OLH    4JGT   
SCOP (Structural Classification of Proteins)3OLH    4JGT   
CATH (Classification of proteins structures)3OLH    4JGT   
SuperfamilyP25325
AlphaFold pdb e-kbP25325   
Human Protein Atlas [tissue]ENSG00000128309-MPST [tissue]
HPRD11896
Protein Interaction databases
DIP (DOE-UCLA)P25325
IntAct (EBI)P25325
BioGRIDMPST
STRING (EMBL)MPST
ZODIACMPST
Ontologies - Pathways
QuickGOP25325
Ontology : AmiGOsulfur amino acid catabolic process  kidney development  liver development  thiosulfate sulfurtransferase activity  protein binding  mitochondrion  mitochondrial matrix  cytosol  cyanate catabolic process  response to toxic substance  3-mercaptopyruvate sulfurtransferase activity  transsulfuration  spinal cord development  identical protein binding  neuron projection  synapse  extracellular exosome  hydrogen sulfide biosynthetic process  
Ontology : EGO-EBIsulfur amino acid catabolic process  kidney development  liver development  thiosulfate sulfurtransferase activity  protein binding  mitochondrion  mitochondrial matrix  cytosol  cyanate catabolic process  response to toxic substance  3-mercaptopyruvate sulfurtransferase activity  transsulfuration  spinal cord development  identical protein binding  neuron projection  synapse  extracellular exosome  hydrogen sulfide biosynthetic process  
Pathways : KEGGCysteine metabolism   
NDEx NetworkMPST
Atlas of Cancer Signalling NetworkMPST
Wikipedia pathwaysMPST
Orthology - Evolution
OrthoDB4357
GeneTree (enSembl)ENSG00000128309
Phylogenetic Trees/Animal Genes : TreeFamMPST
Homologs : HomoloGeneMPST
Homology/Alignments : Family Browser (UCSC)MPST
Gene fusions - Rearrangements
Fusion : QuiverMPST
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMPST [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MPST
dbVarMPST
ClinVarMPST
MonarchMPST
1000_GenomesMPST 
Exome Variant ServerMPST
GNOMAD BrowserENSG00000128309
Varsome BrowserMPST
ACMGMPST variants
VarityP25325
Genomic Variants (DGV)MPST [DGVbeta]
DECIPHERMPST [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMPST 
Mutations
ICGC Data PortalMPST 
TCGA Data PortalMPST 
Broad Tumor PortalMPST
OASIS PortalMPST [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMPST  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMPST
Mutations and Diseases : HGMDMPST
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMPST
DgiDB (Drug Gene Interaction Database)MPST
DoCM (Curated mutations)MPST
CIViC (Clinical Interpretations of Variants in Cancer)MPST
Cancer3DMPST
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602496   
Orphanet
DisGeNETMPST
MedgenMPST
Genetic Testing Registry MPST
NextProtP25325 [Medical]
GENETestsMPST
Target ValidationMPST
Huge Navigator MPST [HugePedia]
ClinGenMPST
Clinical trials, drugs, therapy
MyCancerGenomeMPST
Protein Interactions : CTDMPST
Pharm GKB GenePA30928
PharosP25325
Clinical trialMPST
Miscellaneous
canSAR (ICR)MPST
HarmonizomeMPST
DataMed IndexMPST
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMPST
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:11:31 CEST 2021

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