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MR1 (major histocompatibility complex, class I-related)

Identity

Alias_namesHLALS
major histocompatibility complex
Other alias
HGNC (Hugo) MR1
LocusID (NCBI) 3140
Atlas_Id 51228
Location 1q25.3  [Link to chromosome band 1q25]
Location_base_pair Starts at 181033425 and ends at 181061938 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MR1 (1q25.3) / MR1 (1q25.3)MR1 (1q25.3) / NCKAP5 (2q21.2)PRPSAP2 (17p11.2) / MR1 (1q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MR1   4975
Cards
Entrez_Gene (NCBI)MR1  3140  major histocompatibility complex, class I-related
AliasesHLALS
GeneCards (Weizmann)MR1
Ensembl hg19 (Hinxton)ENSG00000153029 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000153029 [Gene_View]  ENSG00000153029 [Sequence]  chr1:181033425-181061938 [Contig_View]  MR1 [Vega]
ICGC DataPortalENSG00000153029
TCGA cBioPortalMR1
AceView (NCBI)MR1
Genatlas (Paris)MR1
WikiGenes3140
SOURCE (Princeton)MR1
Genetics Home Reference (NIH)MR1
Genomic and cartography
GoldenPath hg38 (UCSC)MR1  -     chr1:181033425-181061938 +  1q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MR1  -     1q25.3   [Description]    (hg19-Feb_2009)
EnsemblMR1 - 1q25.3 [CytoView hg19]  MR1 - 1q25.3 [CytoView hg38]
Mapping of homologs : NCBIMR1 [Mapview hg19]  MR1 [Mapview hg38]
OMIM600764   
Gene and transcription
Genbank (Entrez)AF010446 AF010447 AF031469 AJ249778 AK056155
RefSeq transcript (Entrez)NM_001194999 NM_001195000 NM_001195035 NM_001310213 NM_001531
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MR1
Cluster EST : UnigeneHs.13500 [ NCBI ]
CGAP (NCI)Hs.13500
Alternative Splicing GalleryENSG00000153029
Gene ExpressionMR1 [ NCBI-GEO ]   MR1 [ EBI - ARRAY_EXPRESS ]   MR1 [ SEEK ]   MR1 [ MEM ]
Gene Expression Viewer (FireBrowse)MR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3140
GTEX Portal (Tissue expression)MR1
Human Protein AtlasENSG00000153029-MR1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ95460   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ95460  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ95460
Splice isoforms : SwissVarQ95460
PhosPhoSitePlusQ95460
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    IG_MHC (PS00290)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig/MHC_CS    Ig_C1-set    MHC_I-like_Ag-recog    MHC_I/II-like_Ag-recog    MHC_I_a_a1/a2   
Domain families : Pfam (Sanger)C1-set (PF07654)    MHC_I (PF00129)   
Domain families : Pfam (NCBI)pfam07654    pfam00129   
Domain families : Smart (EMBL)IGc1 (SM00407)  
Conserved Domain (NCBI)MR1
DMDM Disease mutations3140
Blocks (Seattle)MR1
PDB (SRS)4GUP    4L4T    4L4V    4LCW    4NQC    4NQD    4NQE    4PJ5    4PJ7    4PJ8    4PJ9    4PJA    4PJB    4PJC    4PJD    4PJE    4PJF    4PJG    4PJH    4PJI    4PJX    5D5M    5D7I    5D7J    5D7L   
PDB (PDBSum)4GUP    4L4T    4L4V    4LCW    4NQC    4NQD    4NQE    4PJ5    4PJ7    4PJ8    4PJ9    4PJA    4PJB    4PJC    4PJD    4PJE    4PJF    4PJG    4PJH    4PJI    4PJX    5D5M    5D7I    5D7J    5D7L   
PDB (IMB)4GUP    4L4T    4L4V    4LCW    4NQC    4NQD    4NQE    4PJ5    4PJ7    4PJ8    4PJ9    4PJA    4PJB    4PJC    4PJD    4PJE    4PJF    4PJG    4PJH    4PJI    4PJX    5D5M    5D7I    5D7J    5D7L   
PDB (RSDB)4GUP    4L4T    4L4V    4LCW    4NQC    4NQD    4NQE    4PJ5    4PJ7    4PJ8    4PJ9    4PJA    4PJB    4PJC    4PJD    4PJE    4PJF    4PJG    4PJH    4PJI    4PJX    5D5M    5D7I    5D7J    5D7L   
Structural Biology KnowledgeBase4GUP    4L4T    4L4V    4LCW    4NQC    4NQD    4NQE    4PJ5    4PJ7    4PJ8    4PJ9    4PJA    4PJB    4PJC    4PJD    4PJE    4PJF    4PJG    4PJH    4PJI    4PJX    5D5M    5D7I    5D7J    5D7L   
SCOP (Structural Classification of Proteins)4GUP    4L4T    4L4V    4LCW    4NQC    4NQD    4NQE    4PJ5    4PJ7    4PJ8    4PJ9    4PJA    4PJB    4PJC    4PJD    4PJE    4PJF    4PJG    4PJH    4PJI    4PJX    5D5M    5D7I    5D7J    5D7L   
CATH (Classification of proteins structures)4GUP    4L4T    4L4V    4LCW    4NQC    4NQD    4NQE    4PJ5    4PJ7    4PJ8    4PJ9    4PJA    4PJB    4PJC    4PJD    4PJE    4PJF    4PJG    4PJH    4PJI    4PJX    5D5M    5D7I    5D7J    5D7L   
SuperfamilyQ95460
Human Protein Atlas [tissue]ENSG00000153029-MR1 [tissue]
Peptide AtlasQ95460
HPRD09012
IPIIPI00016873   IPI00644740   IPI00025625   IPI00646616   IPI00922150   
Protein Interaction databases
DIP (DOE-UCLA)Q95460
IntAct (EBI)Q95460
FunCoupENSG00000153029
BioGRIDMR1
STRING (EMBL)MR1
ZODIACMR1
Ontologies - Pathways
QuickGOQ95460
Ontology : AmiGOcytokine production involved in immune response  antigen processing and presentation of peptide antigen via MHC class I  protein binding  extracellular region  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  plasma membrane  immune response  signal transduction  integral component of membrane  MHC class I receptor activity  interleukin-1 beta production  interleukin-17 production  MHC class I protein complex  innate immune response  defense response to Gram-negative bacterium  
Ontology : EGO-EBIcytokine production involved in immune response  antigen processing and presentation of peptide antigen via MHC class I  protein binding  extracellular region  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  plasma membrane  immune response  signal transduction  integral component of membrane  MHC class I receptor activity  interleukin-1 beta production  interleukin-17 production  MHC class I protein complex  innate immune response  defense response to Gram-negative bacterium  
NDEx NetworkMR1
Atlas of Cancer Signalling NetworkMR1
Wikipedia pathwaysMR1
Orthology - Evolution
OrthoDB3140
GeneTree (enSembl)ENSG00000153029
Phylogenetic Trees/Animal Genes : TreeFamMR1
HOVERGENQ95460
HOGENOMQ95460
Homologs : HomoloGeneMR1
Homology/Alignments : Family Browser (UCSC)MR1
Gene fusions - Rearrangements
Fusion : QuiverMR1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MR1
dbVarMR1
ClinVarMR1
1000_GenomesMR1 
Exome Variant ServerMR1
ExAC (Exome Aggregation Consortium)ENSG00000153029
GNOMAD BrowserENSG00000153029
Genetic variants : HAPMAP3140
Genomic Variants (DGV)MR1 [DGVbeta]
DECIPHERMR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMR1 
Mutations
ICGC Data PortalMR1 
TCGA Data PortalMR1 
Broad Tumor PortalMR1
OASIS PortalMR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MR1
DgiDB (Drug Gene Interaction Database)MR1
DoCM (Curated mutations)MR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MR1 (select a term)
intoGenMR1
Cancer3DMR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600764   
Orphanet
DisGeNETMR1
MedgenMR1
Genetic Testing Registry MR1
NextProtQ95460 [Medical]
TSGene3140
GENETestsMR1
Target ValidationMR1
Huge Navigator MR1 [HugePedia]
snp3D : Map Gene to Disease3140
BioCentury BCIQMR1
ClinGenMR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3140
Chemical/Pharm GKB GenePA29309
Clinical trialMR1
Miscellaneous
canSAR (ICR)MR1 (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMR1
EVEXMR1
GoPubMedMR1
iHOPMR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:38:29 CEST 2018

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