MRGPRX1 (MAS related GPR family member X1)

2014-11-01 Affiliation

Identity

HGNC

MRGPRX1

LOCATION

11p15.1

LOCUSID

259249

ALIAS

GPCR,MGRG2,MRGX1,SNSR4

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 259249
MIM: 607227
HGNC: 17962
Ensembl: ENSG00000170255

Variants:

dbSNP: 259249
ClinVar: 259249
TCGA: ENSG00000170255
COSMIC: MRGPRX1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000170255	ENST00000302797	Q96LB2
ENSG00000170255	ENST00000302797	W8W3P5
ENSG00000170255	ENST00000526914	A0A494C1K4

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
23074220	2012	Human sensory neuron-specific Mas-related G protein-coupled receptors-X1 sensitize and directly activate transient receptor potential cation channel V1 via distinct signaling pathways.	6
28988117	2018	Mas-Related G-Protein Coupled Receptors and Cowhage-Induced Itch.	2
28223516	2017	Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain.	0
28768771	2017	Activation of mas-related G-protein-coupled receptors by the house dust mite cysteine protease Der p1 provides a new mechanism linking allergy and inflammation.	0

Citation

Dessen P

MRGPRX1 (MAS related GPR family member X1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70415/mrgprx1