MRGPRX3 (MAS related GPR family member X3)

2014-11-01  

Identity

HGNC
MRGPRX3
LOCATION
11p15.1
LOCUSID
117195
ALIAS
GPCR,MRGX3,SNSR1,SNSR2

Other Information

Locus ID:

NCBI: 117195
MIM: 607229
HGNC: 17980
Ensembl: ENSG00000179826

Variants:

dbSNP: 117195
ClinVar: 117195
TCGA: ENSG00000179826
COSMIC: MRGPRX3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000179826ENST00000396275Q96LB0
ENSG00000179826ENST00000531264E9PPY5
ENSG00000179826ENST00000621697Q96LB0

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
281897392017Potential of GPCRs to modulate MAPK and mTOR pathways in Alzheimer's disease.9
294085022018GPR182 is a novel marker for sinusoidal endothelial differentiation with distinct GPCR signaling activity in vitro.2
158090472005Transgenic rats overexpressing the human MrgX3 gene show cataracts and an abnormal skin phenotype.0

Citation

Dessen P

MRGPRX3 (MAS related GPR family member X3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70416/mrgprx3