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MRLN (myoregulin)

Identity

Alias (NCBI)LINC00948
Linc-RAM
M1
MLN
MUSER1
HGNC (Hugo) MRLN
HGNC Alias symbM1
MUSER1
MLN
HGNC Alias namemuscle specific 1
 muscle enriched RNA 1
HGNC Previous nameLINC00948
HGNC Previous namelong intergenic non-protein coding RNA 948
LocusID (NCBI) 100507027
Atlas_Id 77130
Location 10q21.2  [Link to chromosome band 10q21]
Location_base_pair Starts at 59736990 and ends at 59753445 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MRLN   48649
Cards
Entrez_Gene (NCBI)MRLN  100507027  myoregulin
AliasesLINC00948; Linc-RAM; M1; MLN; 
MUSER1
GeneCards (Weizmann)MRLN
Ensembl hg19 (Hinxton)ENSG00000227877 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000227877 [Gene_View]  ENSG00000227877 [Sequence]  chr10:59736990-59753445 [Contig_View]  MRLN [Vega]
ICGC DataPortalENSG00000227877
TCGA cBioPortalMRLN
AceView (NCBI)MRLN
Genatlas (Paris)MRLN
WikiGenes100507027
SOURCE (Princeton)MRLN
Genetics Home Reference (NIH)MRLN
Genomic and cartography
GoldenPath hg38 (UCSC)MRLN  -     chr10:59736990-59753445 -  10q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRLN  -     10q21.2   [Description]    (hg19-Feb_2009)
GoldenPathMRLN - 10q21.2 [CytoView hg19]  MRLN - 10q21.2 [CytoView hg38]
ImmunoBaseENSG00000227877
genome Data Viewer NCBIMRLN [Mapview hg19]  
OMIM616246   
Gene and transcription
Genbank (Entrez)AB019391 AF086308 BG210823 BM021470
RefSeq transcript (Entrez)NM_001304731 NM_001304732
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRLN
Alternative Splicing GalleryENSG00000227877
Gene ExpressionMRLN [ NCBI-GEO ]   MRLN [ EBI - ARRAY_EXPRESS ]   MRLN [ SEEK ]   MRLN [ MEM ]
Gene Expression Viewer (FireBrowse)MRLN [ Firebrowse - Broad ]
GenevisibleExpression of MRLN in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)100507027
GTEX Portal (Tissue expression)MRLN
Human Protein AtlasENSG00000227877-MRLN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0DMT0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP0DMT0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP0DMT0
Splice isoforms : SwissVarP0DMT0
PhosPhoSitePlusP0DMT0
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)MRLN
DMDM Disease mutations100507027
Blocks (Seattle)MRLN
SuperfamilyP0DMT0
Human Protein Atlas [tissue]ENSG00000227877-MRLN [tissue]
Peptide AtlasP0DMT0
Protein Interaction databases
DIP (DOE-UCLA)P0DMT0
IntAct (EBI)P0DMT0
FunCoupENSG00000227877
BioGRIDMRLN
STRING (EMBL)MRLN
ZODIACMRLN
Ontologies - Pathways
QuickGOP0DMT0
Ontology : AmiGOenzyme inhibitor activity  response to wounding  integral component of membrane  sarcoplasmic reticulum membrane  negative regulation of catalytic activity  negative regulation of calcium ion binding  negative regulation of calcium-transporting ATPase activity  negative regulation of calcium ion import into sarcoplasmic reticulum  
Ontology : EGO-EBIenzyme inhibitor activity  response to wounding  integral component of membrane  sarcoplasmic reticulum membrane  negative regulation of catalytic activity  negative regulation of calcium ion binding  negative regulation of calcium-transporting ATPase activity  negative regulation of calcium ion import into sarcoplasmic reticulum  
NDEx NetworkMRLN
Atlas of Cancer Signalling NetworkMRLN
Wikipedia pathwaysMRLN
Orthology - Evolution
OrthoDB100507027
GeneTree (enSembl)ENSG00000227877
Phylogenetic Trees/Animal Genes : TreeFamMRLN
HOGENOMP0DMT0
Homologs : HomoloGeneMRLN
Homology/Alignments : Family Browser (UCSC)MRLN
Gene fusions - Rearrangements
Fusion : QuiverMRLN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRLN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRLN
dbVarMRLN
ClinVarMRLN
1000_GenomesMRLN 
Exome Variant ServerMRLN
GNOMAD BrowserENSG00000227877
Varsome BrowserMRLN
Genetic variants : HAPMAP100507027
Genomic Variants (DGV)MRLN [DGVbeta]
DECIPHERMRLN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRLN 
Mutations
ICGC Data PortalMRLN 
TCGA Data PortalMRLN 
Broad Tumor PortalMRLN
OASIS PortalMRLN [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMRLN
BioMutasearch MRLN
DgiDB (Drug Gene Interaction Database)MRLN
DoCM (Curated mutations)MRLN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRLN (select a term)
intoGenMRLN
Cancer3DMRLN(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616246   
Orphanet
DisGeNETMRLN
MedgenMRLN
Genetic Testing Registry MRLN
NextProtP0DMT0 [Medical]
TSGene100507027
GENETestsMRLN
Target ValidationMRLN
Huge Navigator MRLN [HugePedia]
snp3D : Map Gene to Disease100507027
BioCentury BCIQMRLN
ClinGenMRLN
Clinical trials, drugs, therapy
Protein Interactions : CTD100507027
Clinical trialMRLN
Miscellaneous
canSAR (ICR)MRLN (select the gene name)
HarmonizomeMRLN
DataMed IndexMRLN
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRLN
EVEXMRLN
GoPubMedMRLN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 16:18:25 CEST 2020
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