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MROH2A (maestro heat like repeat family member 2A)

Identity

Alias_namesHEATR7B1
HEAT repeat containing 7B1
maestro heat-like repeat family member 2A
Other alias
HGNC (Hugo) MROH2A
LocusID (NCBI) 339766
Atlas_Id 70422
Location 2q37.1  [Link to chromosome band 2q37]
Location_base_pair Starts at 233775679 and ends at 233833423 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GIGYF2 (2q37.1) / MROH2A (2q37.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(2;2)(q37;q37) GIGYF2/MROH2A

External links

Nomenclature
HGNC (Hugo)MROH2A   27936
Cards
Entrez_Gene (NCBI)MROH2A  339766  maestro heat like repeat family member 2A
AliasesHEATR7B1
GeneCards (Weizmann)MROH2A
Ensembl hg19 (Hinxton)ENSG00000185038 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185038 [Gene_View]  chr2:233775679-233833423 [Contig_View]  MROH2A [Vega]
ICGC DataPortalENSG00000185038
TCGA cBioPortalMROH2A
AceView (NCBI)MROH2A
Genatlas (Paris)MROH2A
WikiGenes339766
SOURCE (Princeton)MROH2A
Genetics Home Reference (NIH)MROH2A
Genomic and cartography
GoldenPath hg38 (UCSC)MROH2A  -     chr2:233775679-233833423 +  2q37.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MROH2A  -     2q37.1   [Description]    (hg19-Feb_2009)
EnsemblMROH2A - 2q37.1 [CytoView hg19]  MROH2A - 2q37.1 [CytoView hg38]
Mapping of homologs : NCBIMROH2A [Mapview hg19]  MROH2A [Mapview hg38]
Gene and transcription
Genbank (Entrez)BC042133 DQ655967 DQ655968 DQ655969
RefSeq transcript (Entrez)NM_001287395
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MROH2A
Cluster EST : UnigeneHs.736887 [ NCBI ]
CGAP (NCI)Hs.736887
Alternative Splicing GalleryENSG00000185038
Gene ExpressionMROH2A [ NCBI-GEO ]   MROH2A [ EBI - ARRAY_EXPRESS ]   MROH2A [ SEEK ]   MROH2A [ MEM ]
Gene Expression Viewer (FireBrowse)MROH2A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)339766
GTEX Portal (Tissue expression)MROH2A
Human Protein AtlasENSG00000185038-MROH2A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA6NES4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA6NES4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA6NES4
Splice isoforms : SwissVarA6NES4
PhosPhoSitePlusA6NES4
Domains : Interpro (EBI)ARM-type_fold   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)MROH2A
DMDM Disease mutations339766
Blocks (Seattle)MROH2A
SuperfamilyA6NES4
Human Protein Atlas [tissue]ENSG00000185038-MROH2A [tissue]
Peptide AtlasA6NES4
IPIIPI00216817   IPI01026239   IPI00893021   IPI00795883   
Protein Interaction databases
DIP (DOE-UCLA)A6NES4
IntAct (EBI)A6NES4
FunCoupENSG00000185038
BioGRIDMROH2A
STRING (EMBL)MROH2A
ZODIACMROH2A
Ontologies - Pathways
QuickGOA6NES4
Ontology : AmiGO
Ontology : EGO-EBI
NDEx NetworkMROH2A
Atlas of Cancer Signalling NetworkMROH2A
Wikipedia pathwaysMROH2A
Orthology - Evolution
OrthoDB339766
GeneTree (enSembl)ENSG00000185038
Phylogenetic Trees/Animal Genes : TreeFamMROH2A
HOVERGENA6NES4
HOGENOMA6NES4
Homologs : HomoloGeneMROH2A
Homology/Alignments : Family Browser (UCSC)MROH2A
Gene fusions - Rearrangements
Fusion : QuiverMROH2A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMROH2A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MROH2A
dbVarMROH2A
ClinVarMROH2A
1000_GenomesMROH2A 
Exome Variant ServerMROH2A
ExAC (Exome Aggregation Consortium)ENSG00000185038
GNOMAD BrowserENSG00000185038
Genetic variants : HAPMAP339766
Genomic Variants (DGV)MROH2A [DGVbeta]
DECIPHERMROH2A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMROH2A 
Mutations
ICGC Data PortalMROH2A 
TCGA Data PortalMROH2A 
Broad Tumor PortalMROH2A
OASIS PortalMROH2A [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMROH2A
BioMutasearch MROH2A
DgiDB (Drug Gene Interaction Database)MROH2A
DoCM (Curated mutations)MROH2A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MROH2A (select a term)
intoGenMROH2A
Cancer3DMROH2A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETMROH2A
MedgenMROH2A
Genetic Testing Registry MROH2A
NextProtA6NES4 [Medical]
TSGene339766
GENETestsMROH2A
Target ValidationMROH2A
Huge Navigator MROH2A [HugePedia]
snp3D : Map Gene to Disease339766
BioCentury BCIQMROH2A
ClinGenMROH2A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD339766
Chemical/Pharm GKB GenePA164720351
Clinical trialMROH2A
Miscellaneous
canSAR (ICR)MROH2A (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMROH2A
EVEXMROH2A
GoPubMedMROH2A
iHOPMROH2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Feb 23 18:43:35 CET 2018
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