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MRPL10 (mitochondrial ribosomal protein L10)

Identity

Alias_symbol (synonym)RPML8
MRP-L8
L10MT
MRP-L10
MRPL8
MGC17973
Other alias
HGNC (Hugo) MRPL10
LocusID (NCBI) 124995
Atlas_Id 70432
Location 17q21.32  [Link to chromosome band 17q21]
Location_base_pair Starts at 47823272 and ends at 47831541 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MRPL10 (17q21.32) / PLP1 (Xq22.2)RPL23 (17q12) / MRPL10 (17q21.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MRPL10   14055
Cards
Entrez_Gene (NCBI)MRPL10  124995  mitochondrial ribosomal protein L10
AliasesL10MT; MRP-L10; MRP-L8; MRPL8; 
RPML8
GeneCards (Weizmann)MRPL10
Ensembl hg19 (Hinxton)ENSG00000159111 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159111 [Gene_View]  chr17:47823272-47831541 [Contig_View]  MRPL10 [Vega]
ICGC DataPortalENSG00000159111
TCGA cBioPortalMRPL10
AceView (NCBI)MRPL10
Genatlas (Paris)MRPL10
WikiGenes124995
SOURCE (Princeton)MRPL10
Genetics Home Reference (NIH)MRPL10
Genomic and cartography
GoldenPath hg38 (UCSC)MRPL10  -     chr17:47823272-47831541 -  17q21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRPL10  -     17q21.32   [Description]    (hg19-Feb_2009)
EnsemblMRPL10 - 17q21.32 [CytoView hg19]  MRPL10 - 17q21.32 [CytoView hg38]
Mapping of homologs : NCBIMRPL10 [Mapview hg19]  MRPL10 [Mapview hg38]
OMIM611825   
Gene and transcription
Genbank (Entrez)AI221522 AK127167 AK293624 AL558270 AL701268
RefSeq transcript (Entrez)NM_145255 NM_148887
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRPL10
Cluster EST : UnigeneHs.347535 [ NCBI ]
CGAP (NCI)Hs.347535
Alternative Splicing GalleryENSG00000159111
Gene ExpressionMRPL10 [ NCBI-GEO ]   MRPL10 [ EBI - ARRAY_EXPRESS ]   MRPL10 [ SEEK ]   MRPL10 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPL10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)124995
GTEX Portal (Tissue expression)MRPL10
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z7H8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z7H8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z7H8
Splice isoforms : SwissVarQ7Z7H8
PhosPhoSitePlusQ7Z7H8
Domains : Interpro (EBI)Ribosomal_L10P   
Domain families : Pfam (Sanger)Ribosomal_L10 (PF00466)   
Domain families : Pfam (NCBI)pfam00466   
Conserved Domain (NCBI)MRPL10
DMDM Disease mutations124995
Blocks (Seattle)MRPL10
PDB (SRS)3J7Y    3J9M   
PDB (PDBSum)3J7Y    3J9M   
PDB (IMB)3J7Y    3J9M   
PDB (RSDB)3J7Y    3J9M   
Structural Biology KnowledgeBase3J7Y    3J9M   
SCOP (Structural Classification of Proteins)3J7Y    3J9M   
CATH (Classification of proteins structures)3J7Y    3J9M   
SuperfamilyQ7Z7H8
Human Protein AtlasENSG00000159111
Peptide AtlasQ7Z7H8
HPRD14738
IPIIPI00376448   IPI00170877   IPI00924872   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z7H8
IntAct (EBI)Q7Z7H8
FunCoupENSG00000159111
BioGRIDMRPL10
STRING (EMBL)MRPL10
ZODIACMRPL10
Ontologies - Pathways
QuickGOQ7Z7H8
Ontology : AmiGORNA binding  structural constituent of ribosome  structural constituent of ribosome  protein binding  nucleoplasm  mitochondrion  mitochondrial inner membrane  mitochondrial large ribosomal subunit  mitochondrial large ribosomal subunit  translation  intracellular ribonucleoprotein complex  mitochondrial translation  ribosome biogenesis  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBIRNA binding  structural constituent of ribosome  structural constituent of ribosome  protein binding  nucleoplasm  mitochondrion  mitochondrial inner membrane  mitochondrial large ribosomal subunit  mitochondrial large ribosomal subunit  translation  intracellular ribonucleoprotein complex  mitochondrial translation  ribosome biogenesis  mitochondrial translational elongation  mitochondrial translational termination  
Pathways : KEGGRibosome   
NDEx NetworkMRPL10
Atlas of Cancer Signalling NetworkMRPL10
Wikipedia pathwaysMRPL10
Orthology - Evolution
OrthoDB124995
GeneTree (enSembl)ENSG00000159111
Phylogenetic Trees/Animal Genes : TreeFamMRPL10
HOVERGENQ7Z7H8
HOGENOMQ7Z7H8
Homologs : HomoloGeneMRPL10
Homology/Alignments : Family Browser (UCSC)MRPL10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPL10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPL10
dbVarMRPL10
ClinVarMRPL10
1000_GenomesMRPL10 
Exome Variant ServerMRPL10
ExAC (Exome Aggregation Consortium)MRPL10 (select the gene name)
Genetic variants : HAPMAP124995
Genomic Variants (DGV)MRPL10 [DGVbeta]
DECIPHERMRPL10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRPL10 
Mutations
ICGC Data PortalMRPL10 
TCGA Data PortalMRPL10 
Broad Tumor PortalMRPL10
OASIS PortalMRPL10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRPL10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMRPL10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MRPL10
DgiDB (Drug Gene Interaction Database)MRPL10
DoCM (Curated mutations)MRPL10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRPL10 (select a term)
intoGenMRPL10
Cancer3DMRPL10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611825   
Orphanet
MedgenMRPL10
Genetic Testing Registry MRPL10
NextProtQ7Z7H8 [Medical]
TSGene124995
GENETestsMRPL10
Target ValidationMRPL10
Huge Navigator MRPL10 [HugePedia]
snp3D : Map Gene to Disease124995
BioCentury BCIQMRPL10
ClinGenMRPL10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD124995
Chemical/Pharm GKB GenePA30939
Clinical trialMRPL10
Miscellaneous
canSAR (ICR)MRPL10 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRPL10
EVEXMRPL10
GoPubMedMRPL10
iHOPMRPL10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:31:09 CEST 2017

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