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MRPL2 (mitochondrial ribosomal protein L2)

Identity

Alias_symbol (synonym)MRP-L14
RPML14
CGI-22
Other alias
HGNC (Hugo) MRPL2
LocusID (NCBI) 51069
Atlas_Id 70442
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 43054029 and ends at 43059545 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MRPL2   14056
Cards
Entrez_Gene (NCBI)MRPL2  51069  mitochondrial ribosomal protein L2
AliasesCGI-22; MRP-L14; RPML14
GeneCards (Weizmann)MRPL2
Ensembl hg19 (Hinxton)ENSG00000112651 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112651 [Gene_View]  ENSG00000112651 [Sequence]  chr6:43054029-43059545 [Contig_View]  MRPL2 [Vega]
ICGC DataPortalENSG00000112651
TCGA cBioPortalMRPL2
AceView (NCBI)MRPL2
Genatlas (Paris)MRPL2
WikiGenes51069
SOURCE (Princeton)MRPL2
Genetics Home Reference (NIH)MRPL2
Genomic and cartography
GoldenPath hg38 (UCSC)MRPL2  -     chr6:43054029-43059545 -  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRPL2  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblMRPL2 - 6p21.1 [CytoView hg19]  MRPL2 - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBIMRPL2 [Mapview hg19]  MRPL2 [Mapview hg38]
OMIM611822   
Gene and transcription
Genbank (Entrez)AA627551 AF086160 AF132956 AK301041 AK307208
RefSeq transcript (Entrez)NM_001300848 NM_015950
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRPL2
Cluster EST : UnigeneHs.55041 [ NCBI ]
CGAP (NCI)Hs.55041
Alternative Splicing GalleryENSG00000112651
Gene ExpressionMRPL2 [ NCBI-GEO ]   MRPL2 [ EBI - ARRAY_EXPRESS ]   MRPL2 [ SEEK ]   MRPL2 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51069
GTEX Portal (Tissue expression)MRPL2
Human Protein AtlasENSG00000112651-MRPL2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T653   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T653  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T653
Splice isoforms : SwissVarQ5T653
PhosPhoSitePlusQ5T653
Domains : Interpro (EBI)NA-bd_OB-fold    Rbsml_prot_L2_RNA-bd_dom    Rib_L2_dom2    Ribosomal_L2    Ribosomal_L2_C    Ribosomal_L2_dom3    Translation_prot_SH3-like   
Domain families : Pfam (Sanger)Ribosomal_L2 (PF00181)    Ribosomal_L2_C (PF03947)   
Domain families : Pfam (NCBI)pfam00181    pfam03947   
Domain families : Smart (EMBL)Ribosomal_L2 (SM01383)  Ribosomal_L2_C (SM01382)  
Conserved Domain (NCBI)MRPL2
DMDM Disease mutations51069
Blocks (Seattle)MRPL2
PDB (SRS)3J7Y    3J9M   
PDB (PDBSum)3J7Y    3J9M   
PDB (IMB)3J7Y    3J9M   
PDB (RSDB)3J7Y    3J9M   
Structural Biology KnowledgeBase3J7Y    3J9M   
SCOP (Structural Classification of Proteins)3J7Y    3J9M   
CATH (Classification of proteins structures)3J7Y    3J9M   
SuperfamilyQ5T653
Human Protein Atlas [tissue]ENSG00000112651-MRPL2 [tissue]
Peptide AtlasQ5T653
HPRD14745
IPIIPI00411816   IPI00909438   IPI00946265   IPI00945936   IPI00946567   
Protein Interaction databases
DIP (DOE-UCLA)Q5T653
IntAct (EBI)Q5T653
FunCoupENSG00000112651
BioGRIDMRPL2
STRING (EMBL)MRPL2
ZODIACMRPL2
Ontologies - Pathways
QuickGOQ5T653
Ontology : AmiGOcytoplasmic translation  RNA binding  structural constituent of ribosome  mitochondrial inner membrane  mitochondrial large ribosomal subunit  mitochondrial translation  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBIcytoplasmic translation  RNA binding  structural constituent of ribosome  mitochondrial inner membrane  mitochondrial large ribosomal subunit  mitochondrial translation  mitochondrial translational elongation  mitochondrial translational termination  
NDEx NetworkMRPL2
Atlas of Cancer Signalling NetworkMRPL2
Wikipedia pathwaysMRPL2
Orthology - Evolution
OrthoDB51069
GeneTree (enSembl)ENSG00000112651
Phylogenetic Trees/Animal Genes : TreeFamMRPL2
HOVERGENQ5T653
HOGENOMQ5T653
Homologs : HomoloGeneMRPL2
Homology/Alignments : Family Browser (UCSC)MRPL2
Gene fusions - Rearrangements
Fusion : QuiverMRPL2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPL2
dbVarMRPL2
ClinVarMRPL2
1000_GenomesMRPL2 
Exome Variant ServerMRPL2
ExAC (Exome Aggregation Consortium)ENSG00000112651
GNOMAD BrowserENSG00000112651
Varsome BrowserMRPL2
Genetic variants : HAPMAP51069
Genomic Variants (DGV)MRPL2 [DGVbeta]
DECIPHERMRPL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRPL2 
Mutations
ICGC Data PortalMRPL2 
TCGA Data PortalMRPL2 
Broad Tumor PortalMRPL2
OASIS PortalMRPL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRPL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMRPL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MRPL2
DgiDB (Drug Gene Interaction Database)MRPL2
DoCM (Curated mutations)MRPL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRPL2 (select a term)
intoGenMRPL2
Cancer3DMRPL2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611822   
Orphanet
DisGeNETMRPL2
MedgenMRPL2
Genetic Testing Registry MRPL2
NextProtQ5T653 [Medical]
TSGene51069
GENETestsMRPL2
Target ValidationMRPL2
Huge Navigator MRPL2 [HugePedia]
snp3D : Map Gene to Disease51069
BioCentury BCIQMRPL2
ClinGenMRPL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51069
Chemical/Pharm GKB GenePA30949
Clinical trialMRPL2
Miscellaneous
canSAR (ICR)MRPL2 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRPL2
EVEXMRPL2
GoPubMedMRPL2
iHOPMRPL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Jul 30 14:18:29 CEST 2018

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