Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MRPL21 (mitochondrial ribosomal protein L21)

Identity

Alias (NCBI)L21mt
MRP-L21
HGNC (Hugo) MRPL21
LocusID (NCBI) 219927
Atlas_Id 56671
Location 11q13.3  [Link to chromosome band 11q13]
Location_base_pair Starts at 68891278 and ends at 68903832 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FSTL5 (4q32.2) / MRPL21 (11q13.3)H19 (11p15.5) / MRPL21 (11q13.3)MRPL21 (11q13.3) / FAM168A (11q13.4)
MRPL21 (11q13.3) / LRP5 (11q13.2)MRPL21 (11q13.3) / MYO1B (2q32.3)MRPL21 (11q13.3) / SSH3 (11q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MRPL21   14479
Cards
Entrez_Gene (NCBI)MRPL21    mitochondrial ribosomal protein L21
AliasesL21mt; MRP-L21
GeneCards (Weizmann)MRPL21
Ensembl hg19 (Hinxton)ENSG00000197345 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197345 [Gene_View]  ENSG00000197345 [Sequence]  chr11:68891278-68903832 [Contig_View]  MRPL21 [Vega]
ICGC DataPortalENSG00000197345
TCGA cBioPortalMRPL21
AceView (NCBI)MRPL21
Genatlas (Paris)MRPL21
SOURCE (Princeton)MRPL21
Genetics Home Reference (NIH)MRPL21
Genomic and cartography
GoldenPath hg38 (UCSC)MRPL21  -     chr11:68891278-68903832 -  11q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRPL21  -     11q13.3   [Description]    (hg19-Feb_2009)
GoldenPathMRPL21 - 11q13.3 [CytoView hg19]  MRPL21 - 11q13.3 [CytoView hg38]
ImmunoBaseENSG00000197345
Genome Data Viewer NCBIMRPL21 [Mapview hg19]  
OMIM611834   
Gene and transcription
Genbank (Entrez)AK096756 AK301989 AV711404 BC055088 BM916618
RefSeq transcript (Entrez)NM_181512 NM_181513 NM_181514 NM_181515
Consensus coding sequences : CCDS (NCBI)MRPL21
Gene ExpressionMRPL21 [ NCBI-GEO ]   MRPL21 [ EBI - ARRAY_EXPRESS ]   MRPL21 [ SEEK ]   MRPL21 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPL21 [ Firebrowse - Broad ]
GenevisibleExpression of MRPL21 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)219927
GTEX Portal (Tissue expression)MRPL21
Human Protein AtlasENSG00000197345-MRPL21 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z2W9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z2W9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z2W9
PhosPhoSitePlusQ7Z2W9
Domains : Interpro (EBI)L21-like_sf    L21p-like    Ribosomal_L21   
Domain families : Pfam (Sanger)Ribosomal_L21p (PF00829)   
Domain families : Pfam (NCBI)pfam00829   
Conserved Domain (NCBI)MRPL21
PDB (RSDB)3J7Y    3J9M    5OOL    5OOM    6I9R    6NU2    6NU3    6VLZ    6VMI    6ZS9    6ZSA    6ZSB    6ZSC    6ZSD    6ZSE    6ZSG   
PDB Europe3J7Y    3J9M    5OOL    5OOM    6I9R    6NU2    6NU3    6VLZ    6VMI    6ZS9    6ZSA    6ZSB    6ZSC    6ZSD    6ZSE    6ZSG   
PDB (PDBSum)3J7Y    3J9M    5OOL    5OOM    6I9R    6NU2    6NU3    6VLZ    6VMI    6ZS9    6ZSA    6ZSB    6ZSC    6ZSD    6ZSE    6ZSG   
PDB (IMB)3J7Y    3J9M    5OOL    5OOM    6I9R    6NU2    6NU3    6VLZ    6VMI    6ZS9    6ZSA    6ZSB    6ZSC    6ZSD    6ZSE    6ZSG   
Structural Biology KnowledgeBase3J7Y    3J9M    5OOL    5OOM    6I9R    6NU2    6NU3    6VLZ    6VMI    6ZS9    6ZSA    6ZSB    6ZSC    6ZSD    6ZSE    6ZSG   
SCOP (Structural Classification of Proteins)3J7Y    3J9M    5OOL    5OOM    6I9R    6NU2    6NU3    6VLZ    6VMI    6ZS9    6ZSA    6ZSB    6ZSC    6ZSD    6ZSE    6ZSG   
CATH (Classification of proteins structures)3J7Y    3J9M    5OOL    5OOM    6I9R    6NU2    6NU3    6VLZ    6VMI    6ZS9    6ZSA    6ZSB    6ZSC    6ZSD    6ZSE    6ZSG   
SuperfamilyQ7Z2W9
AlphaFold pdb e-kbQ7Z2W9   
Human Protein Atlas [tissue]ENSG00000197345-MRPL21 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q7Z2W9
IntAct (EBI)Q7Z2W9
BioGRIDMRPL21
STRING (EMBL)MRPL21
ZODIACMRPL21
Ontologies - Pathways
QuickGOQ7Z2W9
Ontology : AmiGORNA binding  structural constituent of ribosome  mitochondrion  mitochondrial inner membrane  mitochondrial large ribosomal subunit  mitochondrial large ribosomal subunit  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBIRNA binding  structural constituent of ribosome  mitochondrion  mitochondrial inner membrane  mitochondrial large ribosomal subunit  mitochondrial large ribosomal subunit  mitochondrial translational elongation  mitochondrial translational termination  
Pathways : KEGGRibosome   
NDEx NetworkMRPL21
Atlas of Cancer Signalling NetworkMRPL21
Wikipedia pathwaysMRPL21
Orthology - Evolution
OrthoDB219927
GeneTree (enSembl)ENSG00000197345
Phylogenetic Trees/Animal Genes : TreeFamMRPL21
Homologs : HomoloGeneMRPL21
Homology/Alignments : Family Browser (UCSC)MRPL21
Gene fusions - Rearrangements
Fusion : QuiverMRPL21
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPL21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPL21
dbVarMRPL21
ClinVarMRPL21
MonarchMRPL21
1000_GenomesMRPL21 
Exome Variant ServerMRPL21
GNOMAD BrowserENSG00000197345
Varsome BrowserMRPL21
ACMGMRPL21 variants
VarityQ7Z2W9
Genomic Variants (DGV)MRPL21 [DGVbeta]
DECIPHERMRPL21 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRPL21 
Mutations
ICGC Data PortalMRPL21 
TCGA Data PortalMRPL21 
Broad Tumor PortalMRPL21
OASIS PortalMRPL21 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRPL21  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMRPL21
Mutations and Diseases : HGMDMRPL21
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMRPL21
DgiDB (Drug Gene Interaction Database)MRPL21
DoCM (Curated mutations)MRPL21
CIViC (Clinical Interpretations of Variants in Cancer)MRPL21
Cancer3DMRPL21
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611834   
Orphanet
DisGeNETMRPL21
MedgenMRPL21
Genetic Testing Registry MRPL21
NextProtQ7Z2W9 [Medical]
GENETestsMRPL21
Target ValidationMRPL21
Huge Navigator MRPL21 [HugePedia]
ClinGenMRPL21
Clinical trials, drugs, therapy
MyCancerGenomeMRPL21
Protein Interactions : CTDMRPL21
Pharm GKB GenePA30951
PharosQ7Z2W9
Clinical trialMRPL21
Miscellaneous
canSAR (ICR)MRPL21
HarmonizomeMRPL21
DataMed IndexMRPL21
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMRPL21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:21:16 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.