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MRPL21 (mitochondrial ribosomal protein L21)

Identity

Other aliasL21mt
MRP-L21
HGNC (Hugo) MRPL21
LocusID (NCBI) 219927
Atlas_Id 56671
Location 11q13.3  [Link to chromosome band 11q13]
Location_base_pair Starts at 68658746 and ends at 68671303 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
FSTL5 (4q32.2) / MRPL21 (11q13.3)H19 (11p15.5) / MRPL21 (11q13.3)MRPL21 (11q13.3) / FAM168A (11q13.4)
MRPL21 (11q13.3) / LRP5 (11q13.2)MRPL21 (11q13.3) / MYO1B (2q32.3)MRPL21 (11q13.3) / SSH3 (11q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MRPL21   14479
Cards
Entrez_Gene (NCBI)MRPL21  219927  mitochondrial ribosomal protein L21
AliasesL21mt; MRP-L21
GeneCards (Weizmann)MRPL21
Ensembl hg19 (Hinxton) [Gene_View]  chr11:68658746-68671303 [Contig_View]  MRPL21 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr11:68658746-68671303 [Contig_View]  MRPL21 [Vega]
TCGA cBioPortalMRPL21
AceView (NCBI)MRPL21
Genatlas (Paris)MRPL21
WikiGenes219927
SOURCE (Princeton)MRPL21
Genetics Home Reference (NIH)MRPL21
Genomic and cartography
GoldenPath hg19 (UCSC)MRPL21  -     chr11:68658746-68671303 -  11q13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MRPL21  -     11q13.3   [Description]    (hg38-Dec_2013)
EnsemblMRPL21 - 11q13.3 [CytoView hg19]  MRPL21 - 11q13.3 [CytoView hg38]
Mapping of homologs : NCBIMRPL21 [Mapview hg19]  MRPL21 [Mapview hg38]
OMIM611834   
Gene and transcription
Genbank (Entrez)AK096756 AK301989 AV711404 BC055088 BM916618
RefSeq transcript (Entrez)NM_181512 NM_181513 NM_181514 NM_181515
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRPL21
Cluster EST : UnigeneHs.503047 [ NCBI ]
CGAP (NCI)Hs.503047
Gene ExpressionMRPL21 [ NCBI-GEO ]   MRPL21 [ EBI - ARRAY_EXPRESS ]   MRPL21 [ SEEK ]   MRPL21 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPL21 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)219927
GTEX Portal (Tissue expression)MRPL21
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z2W9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z2W9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z2W9
Splice isoforms : SwissVarQ7Z2W9
PhosPhoSitePlusQ7Z2W9
Domains : Interpro (EBI)L21p-like    Ribosomal_L21   
Domain families : Pfam (Sanger)Ribosomal_L21p (PF00829)   
Domain families : Pfam (NCBI)pfam00829   
Conserved Domain (NCBI)MRPL21
DMDM Disease mutations219927
Blocks (Seattle)MRPL21
PDB (SRS)3J7Y    3J9M   
PDB (PDBSum)3J7Y    3J9M   
PDB (IMB)3J7Y    3J9M   
PDB (RSDB)3J7Y    3J9M   
Structural Biology KnowledgeBase3J7Y    3J9M   
SCOP (Structural Classification of Proteins)3J7Y    3J9M   
CATH (Classification of proteins structures)3J7Y    3J9M   
SuperfamilyQ7Z2W9
Peptide AtlasQ7Z2W9
IPIIPI00909026   IPI00375677   IPI01014945   IPI01012984   IPI01013395   IPI00903193   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z2W9
IntAct (EBI)Q7Z2W9
BioGRIDMRPL21
STRING (EMBL)MRPL21
ZODIACMRPL21
Ontologies - Pathways
QuickGOQ7Z2W9
Ontology : AmiGOstructural constituent of ribosome  mitochondrial inner membrane  mitochondrial large ribosomal subunit  mitochondrial large ribosomal subunit  poly(A) RNA binding  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBIstructural constituent of ribosome  mitochondrial inner membrane  mitochondrial large ribosomal subunit  mitochondrial large ribosomal subunit  poly(A) RNA binding  mitochondrial translational elongation  mitochondrial translational termination  
Pathways : KEGGRibosome   
NDEx NetworkMRPL21
Atlas of Cancer Signalling NetworkMRPL21
Wikipedia pathwaysMRPL21
Orthology - Evolution
OrthoDB219927
Phylogenetic Trees/Animal Genes : TreeFamMRPL21
HOVERGENQ7Z2W9
HOGENOMQ7Z2W9
Homologs : HomoloGeneMRPL21
Homology/Alignments : Family Browser (UCSC)MRPL21
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPL21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPL21
dbVarMRPL21
ClinVarMRPL21
1000_GenomesMRPL21 
Exome Variant ServerMRPL21
ExAC (Exome Aggregation Consortium)MRPL21 (select the gene name)
Genetic variants : HAPMAP219927
Genomic Variants (DGV)MRPL21 [DGVbeta]
DECIPHER (Syndromes)11:68658746-68671303  
CONAN: Copy Number AnalysisMRPL21 
Mutations
ICGC Data PortalMRPL21 
TCGA Data PortalMRPL21 
Broad Tumor PortalMRPL21
OASIS PortalMRPL21 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRPL21  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMRPL21
BioMutasearch MRPL21
DgiDB (Drug Gene Interaction Database)MRPL21
DoCM (Curated mutations)MRPL21 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRPL21 (select a term)
intoGenMRPL21
Cancer3DMRPL21(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611834   
Orphanet
MedgenMRPL21
Genetic Testing Registry MRPL21
NextProtQ7Z2W9 [Medical]
TSGene219927
GENETestsMRPL21
Huge Navigator MRPL21 [HugePedia]
snp3D : Map Gene to Disease219927
BioCentury BCIQMRPL21
ClinGenMRPL21
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD219927
Chemical/Pharm GKB GenePA30951
Clinical trialMRPL21
Miscellaneous
canSAR (ICR)MRPL21 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRPL21
EVEXMRPL21
GoPubMedMRPL21
iHOPMRPL21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:11:02 CEST 2017

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