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MRPL23 (mitochondrial ribosomal protein L23)

Identity

Alias_namesRPL23L
Alias_symbol (synonym)L23MRP
Other aliasRPL23
HGNC (Hugo) MRPL23
LocusID (NCBI) 6150
Atlas_Id 70446
Location 11p15.5  [Link to chromosome band 11p15]
Location_base_pair Starts at 1947272 and ends at 1956609 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MRPL23 (11p15.5) / UBB (17p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MRPL23   10322
Cards
Entrez_Gene (NCBI)MRPL23  6150  mitochondrial ribosomal protein L23
AliasesL23MRP; RPL23; RPL23L
GeneCards (Weizmann)MRPL23
Ensembl hg19 (Hinxton)ENSG00000214026 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000214026 [Gene_View]  chr11:1947272-1956609 [Contig_View]  MRPL23 [Vega]
ICGC DataPortalENSG00000214026
TCGA cBioPortalMRPL23
AceView (NCBI)MRPL23
Genatlas (Paris)MRPL23
WikiGenes6150
SOURCE (Princeton)MRPL23
Genetics Home Reference (NIH)MRPL23
Genomic and cartography
GoldenPath hg38 (UCSC)MRPL23  -     chr11:1947272-1956609 +  11p15.5   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRPL23  -     11p15.5   [Description]    (hg19-Feb_2009)
EnsemblMRPL23 - 11p15.5 [CytoView hg19]  MRPL23 - 11p15.5 [CytoView hg38]
Mapping of homologs : NCBIMRPL23 [Mapview hg19]  MRPL23 [Mapview hg38]
OMIM600789   
Gene and transcription
Genbank (Entrez)AK128774 AK313805 AL833465 BC027710 BM670857
RefSeq transcript (Entrez)NM_021134
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRPL23
Cluster EST : UnigeneHs.3254 [ NCBI ]
CGAP (NCI)Hs.3254
Alternative Splicing GalleryENSG00000214026
Gene ExpressionMRPL23 [ NCBI-GEO ]   MRPL23 [ EBI - ARRAY_EXPRESS ]   MRPL23 [ SEEK ]   MRPL23 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPL23 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6150
GTEX Portal (Tissue expression)MRPL23
Human Protein AtlasENSG00000214026-MRPL23 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16540   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16540  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16540
Splice isoforms : SwissVarQ16540
PhosPhoSitePlusQ16540
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait    Ribosomal_L23/L15e_core_dom    Ribosomal_L25/23   
Domain families : Pfam (Sanger)Ribosomal_L23 (PF00276)   
Domain families : Pfam (NCBI)pfam00276   
Conserved Domain (NCBI)MRPL23
DMDM Disease mutations6150
Blocks (Seattle)MRPL23
PDB (SRS)3J7Y    3J9M   
PDB (PDBSum)3J7Y    3J9M   
PDB (IMB)3J7Y    3J9M   
PDB (RSDB)3J7Y    3J9M   
Structural Biology KnowledgeBase3J7Y    3J9M   
SCOP (Structural Classification of Proteins)3J7Y    3J9M   
CATH (Classification of proteins structures)3J7Y    3J9M   
SuperfamilyQ16540
Human Protein Atlas [tissue]ENSG00000214026-MRPL23 [tissue]
Peptide AtlasQ16540
HPRD02876
IPIIPI00293476   IPI00658024   IPI00853201   IPI00853031   IPI00894530   
Protein Interaction databases
DIP (DOE-UCLA)Q16540
IntAct (EBI)Q16540
FunCoupENSG00000214026
BioGRIDMRPL23
STRING (EMBL)MRPL23
ZODIACMRPL23
Ontologies - Pathways
QuickGOQ16540
Ontology : AmiGOfibrillar center  RNA binding  structural constituent of ribosome  protein binding  mitochondrion  mitochondrial inner membrane  mitochondrial large ribosomal subunit  translation  mitochondrial translation  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBIfibrillar center  RNA binding  structural constituent of ribosome  protein binding  mitochondrion  mitochondrial inner membrane  mitochondrial large ribosomal subunit  translation  mitochondrial translation  mitochondrial translational elongation  mitochondrial translational termination  
Pathways : KEGGRibosome   
NDEx NetworkMRPL23
Atlas of Cancer Signalling NetworkMRPL23
Wikipedia pathwaysMRPL23
Orthology - Evolution
OrthoDB6150
GeneTree (enSembl)ENSG00000214026
Phylogenetic Trees/Animal Genes : TreeFamMRPL23
HOVERGENQ16540
HOGENOMQ16540
Homologs : HomoloGeneMRPL23
Homology/Alignments : Family Browser (UCSC)MRPL23
Gene fusions - Rearrangements
Fusion: Tumor Portal MRPL23
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPL23 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPL23
dbVarMRPL23
ClinVarMRPL23
1000_GenomesMRPL23 
Exome Variant ServerMRPL23
ExAC (Exome Aggregation Consortium)ENSG00000214026
GNOMAD BrowserENSG00000214026
Genetic variants : HAPMAP6150
Genomic Variants (DGV)MRPL23 [DGVbeta]
DECIPHERMRPL23 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRPL23 
Mutations
ICGC Data PortalMRPL23 
TCGA Data PortalMRPL23 
Broad Tumor PortalMRPL23
OASIS PortalMRPL23 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRPL23  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMRPL23
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MRPL23
DgiDB (Drug Gene Interaction Database)MRPL23
DoCM (Curated mutations)MRPL23 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRPL23 (select a term)
intoGenMRPL23
Cancer3DMRPL23(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600789   
Orphanet
MedgenMRPL23
Genetic Testing Registry MRPL23
NextProtQ16540 [Medical]
TSGene6150
GENETestsMRPL23
Target ValidationMRPL23
Huge Navigator MRPL23 [HugePedia]
snp3D : Map Gene to Disease6150
BioCentury BCIQMRPL23
ClinGenMRPL23
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6150
Chemical/Pharm GKB GenePA30953
Clinical trialMRPL23
Miscellaneous
canSAR (ICR)MRPL23 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRPL23
EVEXMRPL23
GoPubMedMRPL23
iHOPMRPL23
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:17:48 CET 2017

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