Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MRPL4 (mitochondrial ribosomal protein L4)

Identity

Alias_symbol (synonym)CGI-28
Other aliasL4mt
HGNC (Hugo) MRPL4
LocusID (NCBI) 51073
Atlas_Id 54467
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 10362640 and ends at 10370721 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MRPL4 (19p13.2) / ECI1 (16p13.3)QPCTL (19q13.32) / MRPL4 (19p13.2)SLC16A3 (17q25.3) / MRPL4 (19p13.2)
STAU1 (20q13.13) / MRPL4 (19p13.2)STAU1 20q13.13 / MRPL4 19p13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MRPL4   14276
Cards
Entrez_Gene (NCBI)MRPL4  51073  mitochondrial ribosomal protein L4
AliasesCGI-28; L4mt
GeneCards (Weizmann)MRPL4
Ensembl hg19 (Hinxton)ENSG00000105364 [Gene_View]  chr19:10362640-10370721 [Contig_View]  MRPL4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000105364 [Gene_View]  chr19:10362640-10370721 [Contig_View]  MRPL4 [Vega]
ICGC DataPortalENSG00000105364
TCGA cBioPortalMRPL4
AceView (NCBI)MRPL4
Genatlas (Paris)MRPL4
WikiGenes51073
SOURCE (Princeton)MRPL4
Genetics Home Reference (NIH)MRPL4
Genomic and cartography
GoldenPath hg19 (UCSC)MRPL4  -     chr19:10362640-10370721 +  19p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MRPL4  -     19p13.2   [Description]    (hg38-Dec_2013)
EnsemblMRPL4 - 19p13.2 [CytoView hg19]  MRPL4 - 19p13.2 [CytoView hg38]
Mapping of homologs : NCBIMRPL4 [Mapview hg19]  MRPL4 [Mapview hg38]
OMIM611823   
Gene and transcription
Genbank (Entrez)AB049635 AF132962 AI092267 AL561917 AY007152
RefSeq transcript (Entrez)NM_015956 NM_146387 NM_146388
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011295 NW_004929414
Consensus coding sequences : CCDS (NCBI)MRPL4
Cluster EST : UnigeneHs.279652 [ NCBI ]
CGAP (NCI)Hs.279652
Alternative Splicing GalleryENSG00000105364
Gene ExpressionMRPL4 [ NCBI-GEO ]   MRPL4 [ EBI - ARRAY_EXPRESS ]   MRPL4 [ SEEK ]   MRPL4 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPL4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51073
GTEX Portal (Tissue expression)MRPL4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BYD3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BYD3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BYD3
Splice isoforms : SwissVarQ9BYD3
PhosPhoSitePlusQ9BYD3
Domains : Interpro (EBI)Ribosomal_L4/L1e    Ribosomal_L4_dom    Ribosomal_uL4/L1e   
Domain families : Pfam (Sanger)Ribosomal_L4 (PF00573)   
Domain families : Pfam (NCBI)pfam00573   
Conserved Domain (NCBI)MRPL4
DMDM Disease mutations51073
Blocks (Seattle)MRPL4
PDB (SRS)3J7Y    3J9M   
PDB (PDBSum)3J7Y    3J9M   
PDB (IMB)3J7Y    3J9M   
PDB (RSDB)3J7Y    3J9M   
Structural Biology KnowledgeBase3J7Y    3J9M   
SCOP (Structural Classification of Proteins)3J7Y    3J9M   
CATH (Classification of proteins structures)3J7Y    3J9M   
SuperfamilyQ9BYD3
Human Protein AtlasENSG00000105364
Peptide AtlasQ9BYD3
HPRD14759
IPIIPI00023334   IPI00107137   
Protein Interaction databases
DIP (DOE-UCLA)Q9BYD3
IntAct (EBI)Q9BYD3
FunCoupENSG00000105364
BioGRIDMRPL4
STRING (EMBL)MRPL4
ZODIACMRPL4
Ontologies - Pathways
QuickGOQ9BYD3
Ontology : AmiGORNA binding  structural constituent of ribosome  protein binding  mitochondrial inner membrane  translation  cytosolic ribosome  poly(A) RNA binding  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBIRNA binding  structural constituent of ribosome  protein binding  mitochondrial inner membrane  translation  cytosolic ribosome  poly(A) RNA binding  mitochondrial translational elongation  mitochondrial translational termination  
Pathways : KEGGRibosome   
NDEx NetworkMRPL4
Atlas of Cancer Signalling NetworkMRPL4
Wikipedia pathwaysMRPL4
Orthology - Evolution
OrthoDB51073
GeneTree (enSembl)ENSG00000105364
Phylogenetic Trees/Animal Genes : TreeFamMRPL4
HOVERGENQ9BYD3
HOGENOMQ9BYD3
Homologs : HomoloGeneMRPL4
Homology/Alignments : Family Browser (UCSC)MRPL4
Gene fusions - Rearrangements
Fusion : MitelmanSLC16A3/MRPL4 [17q25.3/19p13.2]  [t(17;19)(q25;p13)]  
Fusion : MitelmanSTAU1/MRPL4 [20q13.13/19p13.2]  [t(19;20)(p13;q13)]  
Fusion: TCGASTAU1 20q13.13 MRPL4 19p13.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPL4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPL4
dbVarMRPL4
ClinVarMRPL4
1000_GenomesMRPL4 
Exome Variant ServerMRPL4
ExAC (Exome Aggregation Consortium)MRPL4 (select the gene name)
Genetic variants : HAPMAP51073
Genomic Variants (DGV)MRPL4 [DGVbeta]
DECIPHER (Syndromes)19:10362640-10370721  ENSG00000105364
CONAN: Copy Number AnalysisMRPL4 
Mutations
ICGC Data PortalMRPL4 
TCGA Data PortalMRPL4 
Broad Tumor PortalMRPL4
OASIS PortalMRPL4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRPL4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMRPL4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MRPL4
DgiDB (Drug Gene Interaction Database)MRPL4
DoCM (Curated mutations)MRPL4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRPL4 (select a term)
intoGenMRPL4
Cancer3DMRPL4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611823   
Orphanet
MedgenMRPL4
Genetic Testing Registry MRPL4
NextProtQ9BYD3 [Medical]
TSGene51073
GENETestsMRPL4
Huge Navigator MRPL4 [HugePedia]
snp3D : Map Gene to Disease51073
BioCentury BCIQMRPL4
ClinGenMRPL4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51073
Chemical/Pharm GKB GenePA30971
Clinical trialMRPL4
Miscellaneous
canSAR (ICR)MRPL4 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRPL4
EVEXMRPL4
GoPubMedMRPL4
iHOPMRPL4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:11:03 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.