MRPL42 (mitochondrial ribosomal protein L42)

2019-04-01  

Identity

HGNC
MRPL42
LOCATION
12q22
LOCUSID
28977
ALIAS
HSPC204,L31MT,L42MT,MRP-L31,MRP-L42,MRP-S32,MRPL31,MRPS32,PTD007,RPML31,S32MT
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 28977
MIM: 611847
HGNC: 14493
Ensembl: ENSG00000198015

Variants:

dbSNP: 28977
ClinVar: 28977
TCGA: ENSG00000198015
COSMIC: MRPL42

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198015ENST00000358678J3KP21
ENSG00000198015ENST00000393128J3KPP0
ENSG00000198015ENST00000547098S4R2Z7
ENSG00000198015ENST00000548545S4R360
ENSG00000198015ENST00000549561Q9Y6G3
ENSG00000198015ENST00000549561A0A024RBG3
ENSG00000198015ENST00000549982Q9Y6G3
ENSG00000198015ENST00000549982A0A024RBG3
ENSG00000198015ENST00000551396F8VVR0
ENSG00000198015ENST00000552217Q9Y6G3
ENSG00000198015ENST00000552217A0A024RBG3

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
205466122010The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.19
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
295310152018Knockdown of MRPL42 suppresses glioma cell proliferation by inducing cell cycle arrest and apoptosis.1
261079022015[Comparative analysis of the role of CD4(+) and CD8(+) T cells in severe asthma development].0

Citation

Dessen P

MRPL42 (mitochondrial ribosomal protein L42)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57951/mrpl42