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MRPL45 (mitochondrial ribosomal protein L45)

Identity

Alias_symbol (synonym)MGC11321
Other aliasL45mt
MRP-L45
HGNC (Hugo) MRPL45
LocusID (NCBI) 84311
Atlas_Id 54468
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 38297023 and ends at 38323218 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TRPC4AP (20q11.22) / MRPL45 (17q12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MRPL45   16651
Cards
Entrez_Gene (NCBI)MRPL45  84311  mitochondrial ribosomal protein L45
AliasesL45mt; MRP-L45
GeneCards (Weizmann)MRPL45
Ensembl hg19 (Hinxton)ENSG00000278845 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000278845 [Gene_View]  chr17:38297023-38323218 [Contig_View]  MRPL45 [Vega]
ICGC DataPortalENSG00000278845
TCGA cBioPortalMRPL45
AceView (NCBI)MRPL45
Genatlas (Paris)MRPL45
WikiGenes84311
SOURCE (Princeton)MRPL45
Genetics Home Reference (NIH)MRPL45
Genomic and cartography
GoldenPath hg38 (UCSC)MRPL45  -     chr17:38297023-38323218 +  17q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRPL45  -     17q12   [Description]    (hg19-Feb_2009)
EnsemblMRPL45 - 17q12 [CytoView hg19]  MRPL45 - 17q12 [CytoView hg38]
Mapping of homologs : NCBIMRPL45 [Mapview hg19]  MRPL45 [Mapview hg38]
OMIM611850   
Gene and transcription
Genbank (Entrez)AK172741 AK225031 AK293605 BC006235 BC105297
RefSeq transcript (Entrez)NM_001278279 NM_032351
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_187614
Consensus coding sequences : CCDS (NCBI)MRPL45
Cluster EST : UnigeneHs.744110 [ NCBI ]
CGAP (NCI)Hs.744110
Alternative Splicing GalleryENSG00000278845
Gene ExpressionMRPL45 [ NCBI-GEO ]   MRPL45 [ EBI - ARRAY_EXPRESS ]   MRPL45 [ SEEK ]   MRPL45 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPL45 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84311
GTEX Portal (Tissue expression)MRPL45
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BRJ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BRJ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BRJ2
Splice isoforms : SwissVarQ9BRJ2
PhosPhoSitePlusQ9BRJ2
Domains : Interpro (EBI)NTF2-like_dom    Tim44-like_dom   
Domain families : Pfam (Sanger)Tim44 (PF04280)   
Domain families : Pfam (NCBI)pfam04280   
Domain families : Smart (EMBL)Tim44 (SM00978)  
Conserved Domain (NCBI)MRPL45
DMDM Disease mutations84311
Blocks (Seattle)MRPL45
PDB (SRS)3J7Y    3J9M   
PDB (PDBSum)3J7Y    3J9M   
PDB (IMB)3J7Y    3J9M   
PDB (RSDB)3J7Y    3J9M   
Structural Biology KnowledgeBase3J7Y    3J9M   
SCOP (Structural Classification of Proteins)3J7Y    3J9M   
CATH (Classification of proteins structures)3J7Y    3J9M   
SuperfamilyQ9BRJ2
Human Protein AtlasENSG00000278845
Peptide AtlasQ9BRJ2
HPRD14764
IPIIPI00790292   
Protein Interaction databases
DIP (DOE-UCLA)Q9BRJ2
IntAct (EBI)Q9BRJ2
FunCoupENSG00000278845
BioGRIDMRPL45
STRING (EMBL)MRPL45
ZODIACMRPL45
Ontologies - Pathways
QuickGOQ9BRJ2
Ontology : AmiGORNA binding  protein binding  mitochondrial inner membrane  mitochondrial large ribosomal subunit  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBIRNA binding  protein binding  mitochondrial inner membrane  mitochondrial large ribosomal subunit  mitochondrial translational elongation  mitochondrial translational termination  
NDEx NetworkMRPL45
Atlas of Cancer Signalling NetworkMRPL45
Wikipedia pathwaysMRPL45
Orthology - Evolution
OrthoDB84311
GeneTree (enSembl)ENSG00000278845
Phylogenetic Trees/Animal Genes : TreeFamMRPL45
HOVERGENQ9BRJ2
HOGENOMQ9BRJ2
Homologs : HomoloGeneMRPL45
Homology/Alignments : Family Browser (UCSC)MRPL45
Gene fusions - Rearrangements
Fusion : MitelmanTRPC4AP/MRPL45 [20q11.22/17q12]  [t(17;20)(q12;q11)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPL45 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPL45
dbVarMRPL45
ClinVarMRPL45
1000_GenomesMRPL45 
Exome Variant ServerMRPL45
ExAC (Exome Aggregation Consortium)MRPL45 (select the gene name)
Genetic variants : HAPMAP84311
Genomic Variants (DGV)MRPL45 [DGVbeta]
DECIPHERMRPL45 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRPL45 
Mutations
ICGC Data PortalMRPL45 
TCGA Data PortalMRPL45 
Broad Tumor PortalMRPL45
OASIS PortalMRPL45 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMRPL45
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MRPL45
DgiDB (Drug Gene Interaction Database)MRPL45
DoCM (Curated mutations)MRPL45 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRPL45 (select a term)
intoGenMRPL45
Cancer3DMRPL45(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611850   
Orphanet
MedgenMRPL45
Genetic Testing Registry MRPL45
NextProtQ9BRJ2 [Medical]
TSGene84311
GENETestsMRPL45
Target ValidationMRPL45
Huge Navigator MRPL45 [HugePedia]
snp3D : Map Gene to Disease84311
BioCentury BCIQMRPL45
ClinGenMRPL45
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84311
Chemical/Pharm GKB GenePA30977
Clinical trialMRPL45
Miscellaneous
canSAR (ICR)MRPL45 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRPL45
EVEXMRPL45
GoPubMedMRPL45
iHOPMRPL45
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:20:36 CEST 2017

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