MRPL46 (mitochondrial ribosomal protein L46)

2014-11-01  

Identity

HGNC
LOCATION
15q25.3
LOCUSID
ALIAS
C15orf4,LIECG2,P2ECSL
FUSION GENES

Other Information

Locus ID:

NCBI: 26589
MIM: 611851
HGNC: 1192
Ensembl: ENSG00000259494

Variants:

dbSNP: 26589
ClinVar: 26589
TCGA: ENSG00000259494
COSMIC: MRPL46

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000259494ENST00000312475Q9H2W6
ENSG00000259494ENST00000558531A0A087WT90
ENSG00000259494ENST00000559538A0A087WT51
ENSG00000259494ENST00000560703H0YN64

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
117617142001Cloning, mapping and expression analysis of C15orf4, a novel human gene with homology to the yeast mitochondrial ribosomal protein Ym130 gene.1

Citation

Dessen P

MRPL46 (mitochondrial ribosomal protein L46)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70462/mrpl46