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MRPL58 (mitochondrial ribosomal protein L58)

Identity

Alias_namesICT1
immature colon carcinoma transcript 1
Alias_symbol (synonym)DS-1
Other aliasDS1
MRP-L58
HGNC (Hugo) MRPL58
LocusID (NCBI) 3396
Atlas_Id 78537
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 75012664 and ends at 75021261 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MRPL58   5359
Cards
Entrez_Gene (NCBI)MRPL58  3396  mitochondrial ribosomal protein L58
AliasesDS-1; DS1; ICT1; MRP-L58
GeneCards (Weizmann)MRPL58
Ensembl hg19 (Hinxton)ENSG00000167862 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167862 [Gene_View]  chr17:75012664-75021261 [Contig_View]  MRPL58 [Vega]
ICGC DataPortalENSG00000167862
TCGA cBioPortalMRPL58
AceView (NCBI)MRPL58
Genatlas (Paris)MRPL58
WikiGenes3396
SOURCE (Princeton)MRPL58
Genetics Home Reference (NIH)MRPL58
Genomic and cartography
GoldenPath hg38 (UCSC)MRPL58  -     chr17:75012664-75021261 +  17q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRPL58  -     17q25.1   [Description]    (hg19-Feb_2009)
EnsemblMRPL58 - 17q25.1 [CytoView hg19]  MRPL58 - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBIMRPL58 [Mapview hg19]  MRPL58 [Mapview hg38]
OMIM603000   
Gene and transcription
Genbank (Entrez)AK222553 AK314138 BC015335 BI870683 BT007111
RefSeq transcript (Entrez)NM_001303265 NM_001545
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRPL58
Cluster EST : UnigeneHs.407955 [ NCBI ]
CGAP (NCI)Hs.407955
Alternative Splicing GalleryENSG00000167862
Gene ExpressionMRPL58 [ NCBI-GEO ]   MRPL58 [ EBI - ARRAY_EXPRESS ]   MRPL58 [ SEEK ]   MRPL58 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPL58 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3396
GTEX Portal (Tissue expression)MRPL58
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14197   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14197  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14197
Splice isoforms : SwissVarQ14197
Catalytic activity : Enzyme3.1.1.29 [ Enzyme-Expasy ]   3.1.1.293.1.1.29 [ IntEnz-EBI ]   3.1.1.29 [ BRENDA ]   3.1.1.29 [ KEGG ]   
PhosPhoSitePlusQ14197
Domains : Interpro (EBI)Pep_chain_release_fac_I_II   
Domain families : Pfam (Sanger)RF-1 (PF00472)   
Domain families : Pfam (NCBI)pfam00472   
Conserved Domain (NCBI)MRPL58
DMDM Disease mutations3396
Blocks (Seattle)MRPL58
PDB (SRS)3J7Y    3J9M   
PDB (PDBSum)3J7Y    3J9M   
PDB (IMB)3J7Y    3J9M   
PDB (RSDB)3J7Y    3J9M   
Structural Biology KnowledgeBase3J7Y    3J9M   
SCOP (Structural Classification of Proteins)3J7Y    3J9M   
CATH (Classification of proteins structures)3J7Y    3J9M   
SuperfamilyQ14197
Human Protein AtlasENSG00000167862
Peptide AtlasQ14197
HPRD04299
IPIIPI00029114   
Protein Interaction databases
DIP (DOE-UCLA)Q14197
IntAct (EBI)Q14197
FunCoupENSG00000167862
BioGRIDMRPL58
STRING (EMBL)MRPL58
ZODIACMRPL58
Ontologies - Pathways
QuickGOQ14197
Ontology : AmiGOaminoacyl-tRNA hydrolase activity  mitochondrion  mitochondrial inner membrane  mitochondrial matrix  mitochondrial large ribosomal subunit  translation release factor activity, codon nonspecific  mitochondrial translational elongation  mitochondrial translational termination  mitochondrial translational termination  
Ontology : EGO-EBIaminoacyl-tRNA hydrolase activity  mitochondrion  mitochondrial inner membrane  mitochondrial matrix  mitochondrial large ribosomal subunit  translation release factor activity, codon nonspecific  mitochondrial translational elongation  mitochondrial translational termination  mitochondrial translational termination  
NDEx NetworkMRPL58
Atlas of Cancer Signalling NetworkMRPL58
Wikipedia pathwaysMRPL58
Orthology - Evolution
OrthoDB3396
GeneTree (enSembl)ENSG00000167862
Phylogenetic Trees/Animal Genes : TreeFamMRPL58
HOVERGENQ14197
HOGENOMQ14197
Homologs : HomoloGeneMRPL58
Homology/Alignments : Family Browser (UCSC)MRPL58
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPL58 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPL58
dbVarMRPL58
ClinVarMRPL58
1000_GenomesMRPL58 
Exome Variant ServerMRPL58
ExAC (Exome Aggregation Consortium)MRPL58 (select the gene name)
Genetic variants : HAPMAP3396
Genomic Variants (DGV)MRPL58 [DGVbeta]
DECIPHERMRPL58 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRPL58 
Mutations
ICGC Data PortalMRPL58 
TCGA Data PortalMRPL58 
Broad Tumor PortalMRPL58
OASIS PortalMRPL58 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMRPL58
BioMutasearch MRPL58
DgiDB (Drug Gene Interaction Database)MRPL58
DoCM (Curated mutations)MRPL58 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRPL58 (select a term)
intoGenMRPL58
Cancer3DMRPL58(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603000   
Orphanet
MedgenMRPL58
Genetic Testing Registry MRPL58
NextProtQ14197 [Medical]
TSGene3396
GENETestsMRPL58
Target ValidationMRPL58
Huge Navigator MRPL58 [HugePedia]
snp3D : Map Gene to Disease3396
BioCentury BCIQMRPL58
ClinGenMRPL58
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3396
Chemical/Pharm GKB GenePA29607
Clinical trialMRPL58
Miscellaneous
canSAR (ICR)MRPL58 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRPL58
EVEXMRPL58
GoPubMedMRPL58
iHOPMRPL58
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:31:33 CEST 2017

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