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MRPS10 (mitochondrial ribosomal protein S10)

Identity

Alias_symbol (synonym)FLJ10567
Other aliasMRP-S10
PNAS-122
HGNC (Hugo) MRPS10
LocusID (NCBI) 55173
Atlas_Id 53025
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 42206801 and ends at 42217895 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HP (16q22.2) / MRPS10 (6p21.1)HPR (16q22.2) / MRPS10 (6p21.1)MRPS10 (6p21.1) / GUCA1B (6p21.1)
MRPS10 (6p21.1) / HPR (16q22.2)MRPS10 (6p21.1) / PPID (4q32.1)MRPS10 (6p21.1) / SEC13 (3p25.3)
TXNL4B (16q22.2) / MRPS10 (6p21.1)XPO5 (6p21.1) / MRPS10 (6p21.1)XPO5 6p21.1 / MRPS10 6p21.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  Prostate tumors: an overview
XPO5/MRPS10 (6p21)
t(6;16)(p21;q22) MRPS10/HPR


External links

Nomenclature
HGNC (Hugo)MRPS10   14502
Cards
Entrez_Gene (NCBI)MRPS10  55173  mitochondrial ribosomal protein S10
AliasesMRP-S10; PNAS-122
GeneCards (Weizmann)MRPS10
Ensembl hg19 (Hinxton)ENSG00000048544 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000048544 [Gene_View]  ENSG00000048544 [Sequence]  chr6:42206801-42217895 [Contig_View]  MRPS10 [Vega]
ICGC DataPortalENSG00000048544
TCGA cBioPortalMRPS10
AceView (NCBI)MRPS10
Genatlas (Paris)MRPS10
WikiGenes55173
SOURCE (Princeton)MRPS10
Genetics Home Reference (NIH)MRPS10
Genomic and cartography
GoldenPath hg38 (UCSC)MRPS10  -     chr6:42206801-42217895 -  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRPS10  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblMRPS10 - 6p21.1 [CytoView hg19]  MRPS10 - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBIMRPS10 [Mapview hg19]  MRPS10 [Mapview hg38]
OMIM611976   
Gene and transcription
Genbank (Entrez)AF113220 AF277180 AI683142 AI754661 AK001429
RefSeq transcript (Entrez)NM_018141
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRPS10
Cluster EST : UnigeneHs.669022 [ NCBI ]
CGAP (NCI)Hs.669022
Alternative Splicing GalleryENSG00000048544
Gene ExpressionMRPS10 [ NCBI-GEO ]   MRPS10 [ EBI - ARRAY_EXPRESS ]   MRPS10 [ SEEK ]   MRPS10 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPS10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55173
GTEX Portal (Tissue expression)MRPS10
Human Protein AtlasENSG00000048544-MRPS10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP82664   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP82664  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP82664
Splice isoforms : SwissVarP82664
PhosPhoSitePlusP82664
Domains : Interpro (EBI)Ribosomal_S10_dom    Ribosomal_S10_dom_sf   
Domain families : Pfam (Sanger)Ribosomal_S10 (PF00338)   
Domain families : Pfam (NCBI)pfam00338   
Domain families : Smart (EMBL)Ribosomal_S10 (SM01403)  
Conserved Domain (NCBI)MRPS10
DMDM Disease mutations55173
Blocks (Seattle)MRPS10
PDB (SRS)3J9M   
PDB (PDBSum)3J9M   
PDB (IMB)3J9M   
PDB (RSDB)3J9M   
Structural Biology KnowledgeBase3J9M   
SCOP (Structural Classification of Proteins)3J9M   
CATH (Classification of proteins structures)3J9M   
SuperfamilyP82664
Human Protein Atlas [tissue]ENSG00000048544-MRPS10 [tissue]
Peptide AtlasP82664
HPRD14775
IPIIPI00061245   
Protein Interaction databases
DIP (DOE-UCLA)P82664
IntAct (EBI)P82664
FunCoupENSG00000048544
BioGRIDMRPS10
STRING (EMBL)MRPS10
ZODIACMRPS10
Ontologies - Pathways
QuickGOP82664
Ontology : AmiGOmolecular_function  mitochondrial inner membrane  mitochondrial small ribosomal subunit  biological_process  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBImolecular_function  mitochondrial inner membrane  mitochondrial small ribosomal subunit  biological_process  mitochondrial translational elongation  mitochondrial translational termination  
Pathways : KEGGRibosome   
NDEx NetworkMRPS10
Atlas of Cancer Signalling NetworkMRPS10
Wikipedia pathwaysMRPS10
Orthology - Evolution
OrthoDB55173
GeneTree (enSembl)ENSG00000048544
Phylogenetic Trees/Animal Genes : TreeFamMRPS10
HOVERGENP82664
HOGENOMP82664
Homologs : HomoloGeneMRPS10
Homology/Alignments : Family Browser (UCSC)MRPS10
Gene fusions - Rearrangements
Fusion : MitelmanMRPS10/HPR [6p21.1/16q22.2]  
Fusion : MitelmanXPO5/MRPS10 [6p21.1/6p21.1]  [t(6;6)(p21;p21)]  
Fusion PortalXPO5 6p21.1 MRPS10 6p21.1 KIRC
Fusion : QuiverMRPS10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPS10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPS10
dbVarMRPS10
ClinVarMRPS10
1000_GenomesMRPS10 
Exome Variant ServerMRPS10
ExAC (Exome Aggregation Consortium)ENSG00000048544
GNOMAD BrowserENSG00000048544
Varsome BrowserMRPS10
Genetic variants : HAPMAP55173
Genomic Variants (DGV)MRPS10 [DGVbeta]
DECIPHERMRPS10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRPS10 
Mutations
ICGC Data PortalMRPS10 
TCGA Data PortalMRPS10 
Broad Tumor PortalMRPS10
OASIS PortalMRPS10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRPS10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMRPS10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MRPS10
DgiDB (Drug Gene Interaction Database)MRPS10
DoCM (Curated mutations)MRPS10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRPS10 (select a term)
intoGenMRPS10
Cancer3DMRPS10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611976   
Orphanet
DisGeNETMRPS10
MedgenMRPS10
Genetic Testing Registry MRPS10
NextProtP82664 [Medical]
TSGene55173
GENETestsMRPS10
Target ValidationMRPS10
Huge Navigator MRPS10 [HugePedia]
snp3D : Map Gene to Disease55173
BioCentury BCIQMRPS10
ClinGenMRPS10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55173
Chemical/Pharm GKB GenePA30993
Clinical trialMRPS10
Miscellaneous
canSAR (ICR)MRPS10 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRPS10
EVEXMRPS10
GoPubMedMRPS10
iHOPMRPS10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:23:52 CET 2018

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