MRPS12 (mitochondrial ribosomal protein S12)

2009-03-01  

Identity

HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
MPR-S12,MT-RPS12,RPMS12,RPS12,RPSM12

Other Information

Locus ID:

NCBI: 6183
MIM: 603021
HGNC: 10380
Ensembl: ENSG00000128626

Variants:

dbSNP: 6183
ClinVar: 6183
TCGA: ENSG00000128626
COSMIC: MRPS12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128626ENST00000308018O15235
ENSG00000128626ENST00000308018A0A024R0H2
ENSG00000128626ENST00000402029O15235
ENSG00000128626ENST00000402029A0A024R0H2
ENSG00000128626ENST00000407800O15235
ENSG00000128626ENST00000407800A0A024R0H2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
RibosomeKEGGko03010
RibosomeKEGGhsa03010
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
336631222021A novel biomarker, MRPS12 functions as a potential oncogene in ovarian cancer and is a promising prognostic candidate.12
336631222021A novel biomarker, MRPS12 functions as a potential oncogene in ovarian cancer and is a promising prognostic candidate.12
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
194392092009NF-Y influences directionality of transcription from the bidirectional Mrps12/Sarsm promoter in both mouse and human cells.4
194392092009NF-Y influences directionality of transcription from the bidirectional Mrps12/Sarsm promoter in both mouse and human cells.4
187900942008cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins.19
187900942008cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins.19
127061052003Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome.8
127061052003Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome.8

Citation

Dessen P

MRPS12 (mitochondrial ribosomal protein S12)

Atlas Genet Cytogenet Oncol Haematol. 2009-03-01

Online version: http://atlasgeneticsoncology.org/gene/50700/mrps12