Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MRPS18A (mitochondrial ribosomal protein S18A)

Identity

Alias_symbol (synonym)FLJ10548
MRPS18-3
Other aliasHumanS18b
MRP-S18-3
S18bmt
HGNC (Hugo) MRPS18A
LocusID (NCBI) 55168
Atlas_Id 54471
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 43671197 and ends at 43687812 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ZSCAN9 (6p22.1) / MRPS18A (6p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p21;p22) ZSCAN9/MRPS18A


External links

Nomenclature
HGNC (Hugo)MRPS18A   14515
Cards
Entrez_Gene (NCBI)MRPS18A  55168  mitochondrial ribosomal protein S18A
AliasesHumanS18b; MRP-S18-3; MRPS18-3; S18bmt
GeneCards (Weizmann)MRPS18A
Ensembl hg19 (Hinxton)ENSG00000096080 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000096080 [Gene_View]  ENSG00000096080 [Sequence]  chr6:43671197-43687812 [Contig_View]  MRPS18A [Vega]
ICGC DataPortalENSG00000096080
TCGA cBioPortalMRPS18A
AceView (NCBI)MRPS18A
Genatlas (Paris)MRPS18A
WikiGenes55168
SOURCE (Princeton)MRPS18A
Genetics Home Reference (NIH)MRPS18A
Genomic and cartography
GoldenPath hg38 (UCSC)MRPS18A  -     chr6:43671197-43687812 -  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRPS18A  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblMRPS18A - 6p21.1 [CytoView hg19]  MRPS18A - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBIMRPS18A [Mapview hg19]  MRPS18A [Mapview hg38]
OMIM611981   
Gene and transcription
Genbank (Entrez)AB049952 AK001410 AK300757 AK307183 BC010364
RefSeq transcript (Entrez)NM_001193343 NM_018135
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRPS18A
Cluster EST : UnigeneHs.520149 [ NCBI ]
CGAP (NCI)Hs.520149
Alternative Splicing GalleryENSG00000096080
Gene ExpressionMRPS18A [ NCBI-GEO ]   MRPS18A [ EBI - ARRAY_EXPRESS ]   MRPS18A [ SEEK ]   MRPS18A [ MEM ]
Gene Expression Viewer (FireBrowse)MRPS18A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55168
GTEX Portal (Tissue expression)MRPS18A
Human Protein AtlasENSG00000096080-MRPS18A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NVS2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NVS2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NVS2
Splice isoforms : SwissVarQ9NVS2
PhosPhoSitePlusQ9NVS2
Domains : Interpro (EBI)Ribosomal_S18    Ribosomal_S18_sf   
Domain families : Pfam (Sanger)Ribosomal_S18 (PF01084)   
Domain families : Pfam (NCBI)pfam01084   
Domain structure : Prodom (Prabi Lyon)Ribosomal_S18 (PD002239)   
Conserved Domain (NCBI)MRPS18A
DMDM Disease mutations55168
Blocks (Seattle)MRPS18A
PDB (SRS)3J7Y    3J9M    5OOL    5OOM   
PDB (PDBSum)3J7Y    3J9M    5OOL    5OOM   
PDB (IMB)3J7Y    3J9M    5OOL    5OOM   
PDB (RSDB)3J7Y    3J9M    5OOL    5OOM   
Structural Biology KnowledgeBase3J7Y    3J9M    5OOL    5OOM   
SCOP (Structural Classification of Proteins)3J7Y    3J9M    5OOL    5OOM   
CATH (Classification of proteins structures)3J7Y    3J9M    5OOL    5OOM   
SuperfamilyQ9NVS2
Human Protein Atlas [tissue]ENSG00000096080-MRPS18A [tissue]
Peptide AtlasQ9NVS2
HPRD14780
IPIIPI00018691   IPI00513805   IPI00642295   
Protein Interaction databases
DIP (DOE-UCLA)Q9NVS2
IntAct (EBI)Q9NVS2
FunCoupENSG00000096080
BioGRIDMRPS18A
STRING (EMBL)MRPS18A
ZODIACMRPS18A
Ontologies - Pathways
QuickGOQ9NVS2
Ontology : AmiGOstructural constituent of ribosome  structural constituent of ribosome  structural constituent of ribosome  mitochondrial inner membrane  mitochondrial small ribosomal subunit  mitochondrial small ribosomal subunit  translation  cytosolic small ribosomal subunit  mitochondrial translation  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBIstructural constituent of ribosome  structural constituent of ribosome  structural constituent of ribosome  mitochondrial inner membrane  mitochondrial small ribosomal subunit  mitochondrial small ribosomal subunit  translation  cytosolic small ribosomal subunit  mitochondrial translation  mitochondrial translational elongation  mitochondrial translational termination  
Pathways : KEGGRibosome   
NDEx NetworkMRPS18A
Atlas of Cancer Signalling NetworkMRPS18A
Wikipedia pathwaysMRPS18A
Orthology - Evolution
OrthoDB55168
GeneTree (enSembl)ENSG00000096080
Phylogenetic Trees/Animal Genes : TreeFamMRPS18A
HOVERGENQ9NVS2
HOGENOMQ9NVS2
Homologs : HomoloGeneMRPS18A
Homology/Alignments : Family Browser (UCSC)MRPS18A
Gene fusions - Rearrangements
Fusion : MitelmanZSCAN9/MRPS18A [6p22.1/6p21.1]  [t(6;6)(p21;p22)]  
Fusion : QuiverMRPS18A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPS18A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPS18A
dbVarMRPS18A
ClinVarMRPS18A
1000_GenomesMRPS18A 
Exome Variant ServerMRPS18A
ExAC (Exome Aggregation Consortium)ENSG00000096080
GNOMAD BrowserENSG00000096080
Varsome BrowserMRPS18A
Genetic variants : HAPMAP55168
Genomic Variants (DGV)MRPS18A [DGVbeta]
DECIPHERMRPS18A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRPS18A 
Mutations
ICGC Data PortalMRPS18A 
TCGA Data PortalMRPS18A 
Broad Tumor PortalMRPS18A
OASIS PortalMRPS18A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRPS18A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMRPS18A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MRPS18A
DgiDB (Drug Gene Interaction Database)MRPS18A
DoCM (Curated mutations)MRPS18A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRPS18A (select a term)
intoGenMRPS18A
Cancer3DMRPS18A(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611981   
Orphanet
DisGeNETMRPS18A
MedgenMRPS18A
Genetic Testing Registry MRPS18A
NextProtQ9NVS2 [Medical]
TSGene55168
GENETestsMRPS18A
Target ValidationMRPS18A
Huge Navigator MRPS18A [HugePedia]
snp3D : Map Gene to Disease55168
BioCentury BCIQMRPS18A
ClinGenMRPS18A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55168
Chemical/Pharm GKB GenePA31003
Clinical trialMRPS18A
Miscellaneous
canSAR (ICR)MRPS18A (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRPS18A
EVEXMRPS18A
GoPubMedMRPS18A
iHOPMRPS18A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:38:46 CEST 2018

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