Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MRPS21 (mitochondrial ribosomal protein S21)

Identity

Other aliasMDS016
MRP-S21
RPMS21
HGNC (Hugo) MRPS21
LocusID (NCBI) 54460
Atlas_Id 70479
Location 1q21.2  [Link to chromosome band 1q21]
Location_base_pair Starts at 150293842 and ends at 150308979 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MRPS21 (1q21.2) / DAP (5p15.2)MRPS21 (1q21.2) / RPS5 (19q13.43)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MRPS21   14046
Cards
Entrez_Gene (NCBI)MRPS21  54460  mitochondrial ribosomal protein S21
AliasesMDS016; MRP-S21; RPMS21
GeneCards (Weizmann)MRPS21
Ensembl hg19 (Hinxton)ENSG00000266472 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000266472 [Gene_View]  chr1:150293842-150308979 [Contig_View]  MRPS21 [Vega]
ICGC DataPortalENSG00000266472
TCGA cBioPortalMRPS21
AceView (NCBI)MRPS21
Genatlas (Paris)MRPS21
WikiGenes54460
SOURCE (Princeton)MRPS21
Genetics Home Reference (NIH)MRPS21
Genomic and cartography
GoldenPath hg38 (UCSC)MRPS21  -     chr1:150293842-150308979 +  1q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRPS21  -     1q21.2   [Description]    (hg19-Feb_2009)
EnsemblMRPS21 - 1q21.2 [CytoView hg19]  MRPS21 - 1q21.2 [CytoView hg38]
Mapping of homologs : NCBIMRPS21 [Mapview hg19]  MRPS21 [Mapview hg38]
OMIM611984   
Gene and transcription
Genbank (Entrez)AA977333 AB049955 AF182417 AK058101 AK289467
RefSeq transcript (Entrez)NM_018997 NM_031901
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRPS21
Cluster EST : UnigeneHs.405880 [ NCBI ]
CGAP (NCI)Hs.405880
Alternative Splicing GalleryENSG00000266472
Gene ExpressionMRPS21 [ NCBI-GEO ]   MRPS21 [ EBI - ARRAY_EXPRESS ]   MRPS21 [ SEEK ]   MRPS21 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPS21 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54460
GTEX Portal (Tissue expression)MRPS21
Human Protein AtlasENSG00000266472-MRPS21 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP82921   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP82921  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP82921
Splice isoforms : SwissVarP82921
PhosPhoSitePlusP82921
Domains : Interpro (EBI)Ribosomal_S21   
Domain families : Pfam (Sanger)Ribosomal_S21 (PF01165)   
Domain families : Pfam (NCBI)pfam01165   
Conserved Domain (NCBI)MRPS21
DMDM Disease mutations54460
Blocks (Seattle)MRPS21
PDB (SRS)3J9M   
PDB (PDBSum)3J9M   
PDB (IMB)3J9M   
PDB (RSDB)3J9M   
Structural Biology KnowledgeBase3J9M   
SCOP (Structural Classification of Proteins)3J9M   
CATH (Classification of proteins structures)3J9M   
SuperfamilyP82921
Human Protein Atlas [tissue]ENSG00000266472-MRPS21 [tissue]
Peptide AtlasP82921
HPRD14784
IPIIPI00014812   IPI00065084   IPI00028790   
Protein Interaction databases
DIP (DOE-UCLA)P82921
IntAct (EBI)P82921
FunCoupENSG00000266472
BioGRIDMRPS21
STRING (EMBL)MRPS21
ZODIACMRPS21
Ontologies - Pathways
QuickGOP82921
Ontology : AmiGORNA binding  structural constituent of ribosome  structural constituent of ribosome  mitochondrial inner membrane  mitochondrial small ribosomal subunit  translation  mitochondrial translation  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBIRNA binding  structural constituent of ribosome  structural constituent of ribosome  mitochondrial inner membrane  mitochondrial small ribosomal subunit  translation  mitochondrial translation  mitochondrial translational elongation  mitochondrial translational termination  
Pathways : KEGGRibosome   
NDEx NetworkMRPS21
Atlas of Cancer Signalling NetworkMRPS21
Wikipedia pathwaysMRPS21
Orthology - Evolution
OrthoDB54460
GeneTree (enSembl)ENSG00000266472
Phylogenetic Trees/Animal Genes : TreeFamMRPS21
HOVERGENP82921
HOGENOMP82921
Homologs : HomoloGeneMRPS21
Homology/Alignments : Family Browser (UCSC)MRPS21
Gene fusions - Rearrangements
Tumor Fusion PortalMRPS21
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPS21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPS21
dbVarMRPS21
ClinVarMRPS21
1000_GenomesMRPS21 
Exome Variant ServerMRPS21
ExAC (Exome Aggregation Consortium)ENSG00000266472
GNOMAD BrowserENSG00000266472
Genetic variants : HAPMAP54460
Genomic Variants (DGV)MRPS21 [DGVbeta]
DECIPHERMRPS21 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRPS21 
Mutations
ICGC Data PortalMRPS21 
TCGA Data PortalMRPS21 
Broad Tumor PortalMRPS21
OASIS PortalMRPS21 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRPS21  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMRPS21
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MRPS21
DgiDB (Drug Gene Interaction Database)MRPS21
DoCM (Curated mutations)MRPS21 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRPS21 (select a term)
intoGenMRPS21
Cancer3DMRPS21(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611984   
Orphanet
DisGeNETMRPS21
MedgenMRPS21
Genetic Testing Registry MRPS21
NextProtP82921 [Medical]
TSGene54460
GENETestsMRPS21
Target ValidationMRPS21
Huge Navigator MRPS21 [HugePedia]
snp3D : Map Gene to Disease54460
BioCentury BCIQMRPS21
ClinGenMRPS21
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54460
Chemical/Pharm GKB GenePA31009
Clinical trialMRPS21
Miscellaneous
canSAR (ICR)MRPS21 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRPS21
EVEXMRPS21
GoPubMedMRPS21
iHOPMRPS21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:01:53 CET 2017

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