Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MRPS25 (mitochondrial ribosomal protein S25)

Identity

Alias (NCBI)MRP-S25
RPMS25
HGNC (Hugo) MRPS25
HGNC Alias symbMRP-S25
FLJ00023
DKFZp313H0817
RPMS25
HGNC Alias namemitochondrial 28S ribosomal protein S25
LocusID (NCBI) 64432
Atlas_Id 70483
Location 3p25.1  [Link to chromosome band 3p25]
Location_base_pair Starts at 15048512 and ends at 15065337 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CYP19A1 (15q21.2) / MRPS25 (3p25.1)MRPS25 (3p25.1) / CD46 (1q32.2)MRPS25 (3p25.1) / MDC1 (6p21.33)
MRPS25 (3p25.1) / SEC23B (20p11.23)MRPS25 (3p25.1) / VAT1 (17q21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MRPS25   14511
Cards
Entrez_Gene (NCBI)MRPS25  64432  mitochondrial ribosomal protein S25
AliasesMRP-S25; RPMS25
GeneCards (Weizmann)MRPS25
Ensembl hg19 (Hinxton)ENSG00000131368 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131368 [Gene_View]  ENSG00000131368 [Sequence]  chr3:15048512-15065337 [Contig_View]  MRPS25 [Vega]
ICGC DataPortalENSG00000131368
TCGA cBioPortalMRPS25
AceView (NCBI)MRPS25
Genatlas (Paris)MRPS25
WikiGenes64432
SOURCE (Princeton)MRPS25
Genetics Home Reference (NIH)MRPS25
Genomic and cartography
GoldenPath hg38 (UCSC)MRPS25  -     chr3:15048512-15065337 -  3p25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRPS25  -     3p25.1   [Description]    (hg19-Feb_2009)
GoldenPathMRPS25 - 3p25.1 [CytoView hg19]  MRPS25 - 3p25.1 [CytoView hg38]
ImmunoBaseENSG00000131368
genome Data Viewer NCBIMRPS25 [Mapview hg19]  
OMIM611987   
Gene and transcription
Genbank (Entrez)AI288348 AK024433 AK024702 AK098361 AK294123
RefSeq transcript (Entrez)NM_022497
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRPS25
Alternative Splicing GalleryENSG00000131368
Gene ExpressionMRPS25 [ NCBI-GEO ]   MRPS25 [ EBI - ARRAY_EXPRESS ]   MRPS25 [ SEEK ]   MRPS25 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPS25 [ Firebrowse - Broad ]
GenevisibleExpression of MRPS25 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64432
GTEX Portal (Tissue expression)MRPS25
Human Protein AtlasENSG00000131368-MRPS25 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP82663   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP82663  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP82663
Splice isoforms : SwissVarP82663
PhosPhoSitePlusP82663
Domains : Interpro (EBI)MRPS25    Ribosome/NADH_DH    Thioredoxin-like_sf   
Domain families : Pfam (Sanger)L51_S25_CI-B8 (PF05047)   
Domain families : Pfam (NCBI)pfam05047   
Domain families : Smart (EMBL)L51_S25_CI-B8 (SM00916)  
Conserved Domain (NCBI)MRPS25
DMDM Disease mutations64432
Blocks (Seattle)MRPS25
PDB (RSDB)3J9M    6NU2    6NU3   
PDB Europe3J9M    6NU2    6NU3   
PDB (PDBSum)3J9M    6NU2    6NU3   
PDB (IMB)3J9M    6NU2    6NU3   
Structural Biology KnowledgeBase3J9M    6NU2    6NU3   
SCOP (Structural Classification of Proteins)3J9M    6NU2    6NU3   
CATH (Classification of proteins structures)3J9M    6NU2    6NU3   
SuperfamilyP82663
Human Protein Atlas [tissue]ENSG00000131368-MRPS25 [tissue]
Peptide AtlasP82663
HPRD17594
IPIIPI00013167   IPI00927346   IPI00796072   IPI00926139   
Protein Interaction databases
DIP (DOE-UCLA)P82663
IntAct (EBI)P82663
FunCoupENSG00000131368
BioGRIDMRPS25
STRING (EMBL)MRPS25
ZODIACMRPS25
Ontologies - Pathways
QuickGOP82663
Ontology : AmiGOstructural constituent of ribosome  mitochondrion  mitochondrion  mitochondrial inner membrane  ribosome  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBIstructural constituent of ribosome  mitochondrion  mitochondrion  mitochondrial inner membrane  ribosome  mitochondrial translational elongation  mitochondrial translational termination  
NDEx NetworkMRPS25
Atlas of Cancer Signalling NetworkMRPS25
Wikipedia pathwaysMRPS25
Orthology - Evolution
OrthoDB64432
GeneTree (enSembl)ENSG00000131368
Phylogenetic Trees/Animal Genes : TreeFamMRPS25
HOGENOMP82663
Homologs : HomoloGeneMRPS25
Homology/Alignments : Family Browser (UCSC)MRPS25
Gene fusions - Rearrangements
Fusion : QuiverMRPS25
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPS25 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPS25
dbVarMRPS25
ClinVarMRPS25
1000_GenomesMRPS25 
Exome Variant ServerMRPS25
GNOMAD BrowserENSG00000131368
Varsome BrowserMRPS25
Genetic variants : HAPMAP64432
Genomic Variants (DGV)MRPS25 [DGVbeta]
DECIPHERMRPS25 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRPS25 
Mutations
ICGC Data PortalMRPS25 
TCGA Data PortalMRPS25 
Broad Tumor PortalMRPS25
OASIS PortalMRPS25 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRPS25  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMRPS25
Mutations and Diseases : HGMDMRPS25
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MRPS25
DgiDB (Drug Gene Interaction Database)MRPS25
DoCM (Curated mutations)MRPS25 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRPS25 (select a term)
intoGenMRPS25
Cancer3DMRPS25(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611987   
Orphanet
DisGeNETMRPS25
MedgenMRPS25
Genetic Testing Registry MRPS25
NextProtP82663 [Medical]
TSGene64432
GENETestsMRPS25
Target ValidationMRPS25
Huge Navigator MRPS25 [HugePedia]
snp3D : Map Gene to Disease64432
BioCentury BCIQMRPS25
ClinGenMRPS25
Clinical trials, drugs, therapy
Protein Interactions : CTD64432
Pharm GKB GenePA31013
Clinical trialMRPS25
Miscellaneous
canSAR (ICR)MRPS25 (select the gene name)
HarmonizomeMRPS25
DataMed IndexMRPS25
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRPS25
EVEXMRPS25
GoPubMedMRPS25
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 16:18:37 CEST 2020

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