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MRPS28 (mitochondrial ribosomal protein S28)

Identity

Alias_symbol (synonym)MRP-S28
HSPC007
MRPS35
Other aliasMRP-S35
HGNC (Hugo) MRPS28
LocusID (NCBI) 28957
Atlas_Id 54473
Location 8q21.13  [Link to chromosome band 8q21]
Location_base_pair Starts at 79918860 and ends at 80030271 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MAMDC2 (9q21.12) / MRPS28 (8q21.13)MRPS28 (8q21.13) / ADAMTS16 (5p15.32)MRPS28 (8q21.13) / ARFGEF1 (8q13.2)
MRPS28 (8q21.13) / HIST1H2AC (6p22.2)MRPS28 (8q21.13) / TPD52 (8q21.13)MAMDC2 9q21.12 / MRPS28 8q21.13
MRPS28 8q21.13 / HIST1H2AC 6p22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)MRPS28   14513
Cards
Entrez_Gene (NCBI)MRPS28  28957  mitochondrial ribosomal protein S28
AliasesHSPC007; MRP-S28; MRP-S35; MRPS35
GeneCards (Weizmann)MRPS28
Ensembl hg19 (Hinxton)ENSG00000147586 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147586 [Gene_View]  chr8:79918860-80030271 [Contig_View]  MRPS28 [Vega]
ICGC DataPortalENSG00000147586
TCGA cBioPortalMRPS28
AceView (NCBI)MRPS28
Genatlas (Paris)MRPS28
WikiGenes28957
SOURCE (Princeton)MRPS28
Genetics Home Reference (NIH)MRPS28
Genomic and cartography
GoldenPath hg38 (UCSC)MRPS28  -     chr8:79918860-80030271 -  8q21.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRPS28  -     8q21.13   [Description]    (hg19-Feb_2009)
EnsemblMRPS28 - 8q21.13 [CytoView hg19]  MRPS28 - 8q21.13 [CytoView hg38]
Mapping of homologs : NCBIMRPS28 [Mapview hg19]  MRPS28 [Mapview hg38]
OMIM611990   
Gene and transcription
Genbank (Entrez)AF070663 AK026506 AK223069 AK315739 BC010150
RefSeq transcript (Entrez)NM_014018
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRPS28
Cluster EST : UnigeneHs.521124 [ NCBI ]
CGAP (NCI)Hs.521124
Alternative Splicing GalleryENSG00000147586
Gene ExpressionMRPS28 [ NCBI-GEO ]   MRPS28 [ EBI - ARRAY_EXPRESS ]   MRPS28 [ SEEK ]   MRPS28 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPS28 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)28957
GTEX Portal (Tissue expression)MRPS28
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2Q9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2Q9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2Q9
Splice isoforms : SwissVarQ9Y2Q9
PhosPhoSitePlusQ9Y2Q9
Domains : Interpro (EBI)Ribosomal_S28_mit   
Domain families : Pfam (Sanger)MRP-S35 (PF10246)   
Domain families : Pfam (NCBI)pfam10246   
Conserved Domain (NCBI)MRPS28
DMDM Disease mutations28957
Blocks (Seattle)MRPS28
PDB (SRS)3J9M   
PDB (PDBSum)3J9M   
PDB (IMB)3J9M   
PDB (RSDB)3J9M   
Structural Biology KnowledgeBase3J9M   
SCOP (Structural Classification of Proteins)3J9M   
CATH (Classification of proteins structures)3J9M   
SuperfamilyQ9Y2Q9
Human Protein AtlasENSG00000147586
Peptide AtlasQ9Y2Q9
HPRD10097
IPIIPI00022276   IPI01010223   IPI00978699   IPI00974472   IPI00795057   IPI01009798   IPI00981999   IPI00973925   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2Q9
IntAct (EBI)Q9Y2Q9
FunCoupENSG00000147586
BioGRIDMRPS28
STRING (EMBL)MRPS28
ZODIACMRPS28
Ontologies - Pathways
QuickGOQ9Y2Q9
Ontology : AmiGORNA binding  mitochondrion  mitochondrial inner membrane  mitochondrial small ribosomal subunit  biological_process  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBIRNA binding  mitochondrion  mitochondrial inner membrane  mitochondrial small ribosomal subunit  biological_process  mitochondrial translational elongation  mitochondrial translational termination  
NDEx NetworkMRPS28
Atlas of Cancer Signalling NetworkMRPS28
Wikipedia pathwaysMRPS28
Orthology - Evolution
OrthoDB28957
GeneTree (enSembl)ENSG00000147586
Phylogenetic Trees/Animal Genes : TreeFamMRPS28
HOVERGENQ9Y2Q9
HOGENOMQ9Y2Q9
Homologs : HomoloGeneMRPS28
Homology/Alignments : Family Browser (UCSC)MRPS28
Gene fusions - Rearrangements
Fusion : MitelmanMAMDC2/MRPS28 [9q21.12/8q21.13]  [t(8;9)(q21;q21)]  
Fusion : MitelmanMRPS28/ADAMTS16 [8q21.13/5p15.32]  [t(5;8)(p15;q21)]  
Fusion : MitelmanMRPS28/HIST1H2AC [8q21.13/6p22.2]  [t(6;8)(p22;q21)]  
Fusion: TCGAMAMDC2 9q21.12 MRPS28 8q21.13 HNSC
Fusion: TCGAMRPS28 8q21.13 HIST1H2AC 6p22.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPS28 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPS28
dbVarMRPS28
ClinVarMRPS28
1000_GenomesMRPS28 
Exome Variant ServerMRPS28
ExAC (Exome Aggregation Consortium)MRPS28 (select the gene name)
Genetic variants : HAPMAP28957
Genomic Variants (DGV)MRPS28 [DGVbeta]
DECIPHERMRPS28 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRPS28 
Mutations
ICGC Data PortalMRPS28 
TCGA Data PortalMRPS28 
Broad Tumor PortalMRPS28
OASIS PortalMRPS28 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRPS28  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMRPS28
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MRPS28
DgiDB (Drug Gene Interaction Database)MRPS28
DoCM (Curated mutations)MRPS28 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRPS28 (select a term)
intoGenMRPS28
Cancer3DMRPS28(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611990   
Orphanet
MedgenMRPS28
Genetic Testing Registry MRPS28
NextProtQ9Y2Q9 [Medical]
TSGene28957
GENETestsMRPS28
Target ValidationMRPS28
Huge Navigator MRPS28 [HugePedia]
snp3D : Map Gene to Disease28957
BioCentury BCIQMRPS28
ClinGenMRPS28
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD28957
Chemical/Pharm GKB GenePA31016
Clinical trialMRPS28
Miscellaneous
canSAR (ICR)MRPS28 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRPS28
EVEXMRPS28
GoPubMedMRPS28
iHOPMRPS28
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:20:38 CEST 2017

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