Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MRPS30 (mitochondrial ribosomal protein S30)

Identity

Alias_namesPDCD9
Alias_symbol (synonym)PAP
Other aliasMRP-S30
S30mt
HGNC (Hugo) MRPS30
LocusID (NCBI) 10884
Atlas_Id 43363
Location 5p12  [Link to chromosome band 5p12]
Location_base_pair Starts at 44808925 and ends at 44815516 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MROH2B (5p13.1) / MRPS30 (5p12)MRPS30 (5p12) / LYZ (12q15)MRPS30 (5p12) / MRPS30 (5p12)
HEATR7B2 MRPS30 5p12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(5;5)(p12;p13) MROH2B/MRPS30


External links

Nomenclature
HGNC (Hugo)MRPS30   8769
Cards
Entrez_Gene (NCBI)MRPS30  10884  mitochondrial ribosomal protein S30
AliasesMRP-S30; PAP; PDCD9; S30mt
GeneCards (Weizmann)MRPS30
Ensembl hg19 (Hinxton)ENSG00000112996 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112996 [Gene_View]  ENSG00000112996 [Sequence]  chr5:44808925-44815516 [Contig_View]  MRPS30 [Vega]
ICGC DataPortalENSG00000112996
TCGA cBioPortalMRPS30
AceView (NCBI)MRPS30
Genatlas (Paris)MRPS30
WikiGenes10884
SOURCE (Princeton)MRPS30
Genetics Home Reference (NIH)MRPS30
Genomic and cartography
GoldenPath hg38 (UCSC)MRPS30  -     chr5:44808925-44815516 +  5p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRPS30  -     5p12   [Description]    (hg19-Feb_2009)
EnsemblMRPS30 - 5p12 [CytoView hg19]  MRPS30 - 5p12 [CytoView hg38]
Mapping of homologs : NCBIMRPS30 [Mapview hg19]  MRPS30 [Mapview hg38]
OMIM611991   
Gene and transcription
Genbank (Entrez)AF146192 AF217523 AK074777 AK222704 AK222894
RefSeq transcript (Entrez)NM_016640
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRPS30
Cluster EST : UnigeneHs.124165 [ NCBI ]
CGAP (NCI)Hs.124165
Alternative Splicing GalleryENSG00000112996
Gene ExpressionMRPS30 [ NCBI-GEO ]   MRPS30 [ EBI - ARRAY_EXPRESS ]   MRPS30 [ SEEK ]   MRPS30 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPS30 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10884
GTEX Portal (Tissue expression)MRPS30
Human Protein AtlasENSG00000112996-MRPS30 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NP92   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NP92  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NP92
Splice isoforms : SwissVarQ9NP92
PhosPhoSitePlusQ9NP92
Domains : Interpro (EBI)Ribosomal_L37/S30   
Domain families : Pfam (Sanger)PDCD9 (PF07147)   
Domain families : Pfam (NCBI)pfam07147   
Conserved Domain (NCBI)MRPS30
DMDM Disease mutations10884
Blocks (Seattle)MRPS30
PDB (SRS)3J7Y    3J9M    5OOL    5OOM   
PDB (PDBSum)3J7Y    3J9M    5OOL    5OOM   
PDB (IMB)3J7Y    3J9M    5OOL    5OOM   
PDB (RSDB)3J7Y    3J9M    5OOL    5OOM   
Structural Biology KnowledgeBase3J7Y    3J9M    5OOL    5OOM   
SCOP (Structural Classification of Proteins)3J7Y    3J9M    5OOL    5OOM   
CATH (Classification of proteins structures)3J7Y    3J9M    5OOL    5OOM   
SuperfamilyQ9NP92
Human Protein Atlas [tissue]ENSG00000112996-MRPS30 [tissue]
Peptide AtlasQ9NP92
HPRD17597
IPIIPI00010278   
Protein Interaction databases
DIP (DOE-UCLA)Q9NP92
IntAct (EBI)Q9NP92
FunCoupENSG00000112996
BioGRIDMRPS30
STRING (EMBL)MRPS30
ZODIACMRPS30
Ontologies - Pathways
QuickGOQ9NP92
Ontology : AmiGORNA binding  structural constituent of ribosome  mitochondrial inner membrane  ribosome  apoptotic process  mitochondrial translational elongation  mitochondrial translational termination  
Ontology : EGO-EBIRNA binding  structural constituent of ribosome  mitochondrial inner membrane  ribosome  apoptotic process  mitochondrial translational elongation  mitochondrial translational termination  
NDEx NetworkMRPS30
Atlas of Cancer Signalling NetworkMRPS30
Wikipedia pathwaysMRPS30
Orthology - Evolution
OrthoDB10884
GeneTree (enSembl)ENSG00000112996
Phylogenetic Trees/Animal Genes : TreeFamMRPS30
HOVERGENQ9NP92
HOGENOMQ9NP92
Homologs : HomoloGeneMRPS30
Homology/Alignments : Family Browser (UCSC)MRPS30
Gene fusions - Rearrangements
Fusion : MitelmanMROH2B/MRPS30 [5p13.1/5p12]  [t(5;5)(p12;p13)]  
Fusion PortalHEATR7B2 MRPS30 5p12 LUAD
Fusion : QuiverMRPS30
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPS30 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPS30
dbVarMRPS30
ClinVarMRPS30
1000_GenomesMRPS30 
Exome Variant ServerMRPS30
ExAC (Exome Aggregation Consortium)ENSG00000112996
GNOMAD BrowserENSG00000112996
Varsome BrowserMRPS30
Genetic variants : HAPMAP10884
Genomic Variants (DGV)MRPS30 [DGVbeta]
DECIPHERMRPS30 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRPS30 
Mutations
ICGC Data PortalMRPS30 
TCGA Data PortalMRPS30 
Broad Tumor PortalMRPS30
OASIS PortalMRPS30 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRPS30  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMRPS30
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MRPS30
DgiDB (Drug Gene Interaction Database)MRPS30
DoCM (Curated mutations)MRPS30 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRPS30 (select a term)
intoGenMRPS30
Cancer3DMRPS30(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611991   
Orphanet
DisGeNETMRPS30
MedgenMRPS30
Genetic Testing Registry MRPS30
NextProtQ9NP92 [Medical]
TSGene10884
GENETestsMRPS30
Target ValidationMRPS30
Huge Navigator MRPS30 [HugePedia]
snp3D : Map Gene to Disease10884
BioCentury BCIQMRPS30
ClinGenMRPS30
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10884
Chemical/Pharm GKB GenePA31018
Clinical trialMRPS30
Miscellaneous
canSAR (ICR)MRPS30 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRPS30
EVEXMRPS30
GoPubMedMRPS30
iHOPMRPS30
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:38:47 CEST 2018

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