Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MRPS6 (mitochondrial ribosomal protein S6)

Identity

Alias (NCBI)C21orf101
MRP-S6
RPMS6
S6mt
HGNC (Hugo) MRPS6
HGNC Alias symbMRP-S6
RPMS6
HGNC Previous nameC21orf101
HGNC Previous namechromosome 21 open reading frame 101
LocusID (NCBI) 64968
Atlas_Id 70492
Location 21q22.11  [Link to chromosome band 21q22]
Location_base_pair Starts at 34073578 and ends at 34143030 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DYRK1A (21q22.13) / MRPS6 (21q22.11)MRPS6 (21q22.11) / MRPS6 (21q22.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MRPS6   14051
Cards
Entrez_Gene (NCBI)MRPS6    mitochondrial ribosomal protein S6
AliasesC21orf101; MRP-S6; RPMS6; S6mt
GeneCards (Weizmann)MRPS6
Ensembl hg19 (Hinxton)ENSG00000243927 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000243927 [Gene_View]  ENSG00000243927 [Sequence]  chr21:34073578-34143030 [Contig_View]  MRPS6 [Vega]
ICGC DataPortalENSG00000243927
TCGA cBioPortalMRPS6
AceView (NCBI)MRPS6
Genatlas (Paris)MRPS6
SOURCE (Princeton)MRPS6
Genetics Home Reference (NIH)MRPS6
Genomic and cartography
GoldenPath hg38 (UCSC)MRPS6  -     chr21:34073578-34143030 +  21q22.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRPS6  -     21q22.11   [Description]    (hg19-Feb_2009)
GoldenPathMRPS6 - 21q22.11 [CytoView hg19]  MRPS6 - 21q22.11 [CytoView hg38]
ImmunoBaseENSG00000243927
Genome Data Viewer NCBIMRPS6 [Mapview hg19]  
OMIM611973   
Gene and transcription
Genbank (Entrez)AB049942 AI799469 AK096374 AK312084 AY061855
RefSeq transcript (Entrez)NM_032476
Consensus coding sequences : CCDS (NCBI)MRPS6
Gene ExpressionMRPS6 [ NCBI-GEO ]   MRPS6 [ EBI - ARRAY_EXPRESS ]   MRPS6 [ SEEK ]   MRPS6 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPS6 [ Firebrowse - Broad ]
GenevisibleExpression of MRPS6 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64968
GTEX Portal (Tissue expression)MRPS6
Human Protein AtlasENSG00000243927-MRPS6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP82932   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP82932  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP82932
PhosPhoSitePlusP82932
Domains : Interpro (EBI)Ribosomal_S6    Ribosomal_S6_sf    Transl_elong_EF1B/ribosomal_S6   
Domain families : Pfam (Sanger)Ribosomal_S6 (PF01250)   
Domain families : Pfam (NCBI)pfam01250   
Conserved Domain (NCBI)MRPS6
PDB (RSDB)3J9M    6NU2    6NU3    6RW4    6RW5    6VLZ    6VMI    6ZS9    6ZSA    6ZSB    6ZSC    6ZSD    6ZSE    6ZSG   
PDB Europe3J9M    6NU2    6NU3    6RW4    6RW5    6VLZ    6VMI    6ZS9    6ZSA    6ZSB    6ZSC    6ZSD    6ZSE    6ZSG   
PDB (PDBSum)3J9M    6NU2    6NU3    6RW4    6RW5    6VLZ    6VMI    6ZS9    6ZSA    6ZSB    6ZSC    6ZSD    6ZSE    6ZSG   
PDB (IMB)3J9M    6NU2    6NU3    6RW4    6RW5    6VLZ    6VMI    6ZS9    6ZSA    6ZSB    6ZSC    6ZSD    6ZSE    6ZSG   
Structural Biology KnowledgeBase3J9M    6NU2    6NU3    6RW4    6RW5    6VLZ    6VMI    6ZS9    6ZSA    6ZSB    6ZSC    6ZSD    6ZSE    6ZSG   
SCOP (Structural Classification of Proteins)3J9M    6NU2    6NU3    6RW4    6RW5    6VLZ    6VMI    6ZS9    6ZSA    6ZSB    6ZSC    6ZSD    6ZSE    6ZSG   
CATH (Classification of proteins structures)3J9M    6NU2    6NU3    6RW4    6RW5    6VLZ    6VMI    6ZS9    6ZSA    6ZSB    6ZSC    6ZSD    6ZSE    6ZSG   
SuperfamilyP82932
AlphaFold pdb e-kbP82932   
Human Protein Atlas [tissue]ENSG00000243927-MRPS6 [tissue]
HPRD11374
Protein Interaction databases
DIP (DOE-UCLA)P82932
IntAct (EBI)P82932
BioGRIDMRPS6
STRING (EMBL)MRPS6
ZODIACMRPS6
Ontologies - Pathways
QuickGOP82932
Ontology : AmiGOstructural constituent of ribosome  structural constituent of ribosome  structural constituent of ribosome  protein binding  mitochondrion  mitochondrial inner membrane  mitochondrial small ribosomal subunit  mitochondrial small ribosomal subunit  mitochondrial small ribosomal subunit  translation  small ribosomal subunit  mitochondrial translation  mitochondrial translational elongation  mitochondrial translational termination  small ribosomal subunit rRNA binding  
Ontology : EGO-EBIstructural constituent of ribosome  structural constituent of ribosome  structural constituent of ribosome  protein binding  mitochondrion  mitochondrial inner membrane  mitochondrial small ribosomal subunit  mitochondrial small ribosomal subunit  mitochondrial small ribosomal subunit  translation  small ribosomal subunit  mitochondrial translation  mitochondrial translational elongation  mitochondrial translational termination  small ribosomal subunit rRNA binding  
NDEx NetworkMRPS6
Atlas of Cancer Signalling NetworkMRPS6
Wikipedia pathwaysMRPS6
Orthology - Evolution
OrthoDB64968
GeneTree (enSembl)ENSG00000243927
Phylogenetic Trees/Animal Genes : TreeFamMRPS6
Homologs : HomoloGeneMRPS6
Homology/Alignments : Family Browser (UCSC)MRPS6
Gene fusions - Rearrangements
Fusion : QuiverMRPS6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPS6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPS6
dbVarMRPS6
ClinVarMRPS6
MonarchMRPS6
1000_GenomesMRPS6 
Exome Variant ServerMRPS6
GNOMAD BrowserENSG00000243927
Varsome BrowserMRPS6
ACMGMRPS6 variants
VarityP82932
Genomic Variants (DGV)MRPS6 [DGVbeta]
DECIPHERMRPS6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRPS6 
Mutations
ICGC Data PortalMRPS6 
TCGA Data PortalMRPS6 
Broad Tumor PortalMRPS6
OASIS PortalMRPS6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRPS6  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMRPS6
Mutations and Diseases : HGMDMRPS6
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMRPS6
DgiDB (Drug Gene Interaction Database)MRPS6
DoCM (Curated mutations)MRPS6
CIViC (Clinical Interpretations of Variants in Cancer)MRPS6
Cancer3DMRPS6
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611973   
Orphanet
DisGeNETMRPS6
MedgenMRPS6
Genetic Testing Registry MRPS6
NextProtP82932 [Medical]
GENETestsMRPS6
Target ValidationMRPS6
Huge Navigator MRPS6 [HugePedia]
ClinGenMRPS6
Clinical trials, drugs, therapy
MyCancerGenomeMRPS6
Protein Interactions : CTDMRPS6
Pharm GKB GenePA31025
PharosP82932
Clinical trialMRPS6
Miscellaneous
canSAR (ICR)MRPS6
HarmonizomeMRPS6
DataMed IndexMRPS6
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMRPS6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:11:48 CEST 2021

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