MRRF (mitochondrial ribosome recycling factor)

2014-11-01  

Identity

HGNC
LOCATION
9q33.2
LOCUSID
ALIAS
MRFF,MTRRF,RRF
FUSION GENES

Other Information

Locus ID:

NCBI: 92399
MIM: 604602
HGNC: 7234
Ensembl: ENSG00000148187

Variants:

dbSNP: 92399
ClinVar: 92399
TCGA: ENSG00000148187
COSMIC: MRRF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148187ENST00000297908Q96E11
ENSG00000148187ENST00000344641Q96E11
ENSG00000148187ENST00000373723Q96E11
ENSG00000148187ENST00000373729Q96E11
ENSG00000148187ENST00000394315Q96E11
ENSG00000148187ENST00000441707X6RDS5
ENSG00000148187ENST00000467864Q96E11
ENSG00000148187ENST00000470366Q96E11
ENSG00000148187ENST00000470366A0A024R855
ENSG00000148187ENST00000489572Q96E11
ENSG00000148187ENST00000489572A0A024R855

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
187828332008The human mitochondrial ribosome recycling factor is essential for cell viability.42
197167932009EF-G2mt is an exclusive recycling factor in mammalian mitochondrial protein synthesis.33
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17

Citation

Dessen P

MRRF (mitochondrial ribosome recycling factor)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70495/mrrf