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MRS2 (magnesium transporter MRS2)

Identity

Alias_namesMRS2L
MRS2-like, magnesium homeostasis factor (S. cerevisiae)
MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
Other aliasHPT
HGNC (Hugo) MRS2
LocusID (NCBI) 57380
Atlas_Id 41430
Location 6p22.3  [Link to chromosome band 6p22]
Location_base_pair Starts at 24402908 and ends at 24426194 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LRRC16A (6p22.2) / MRS2 (6p22.3)MRS2 (6p22.3) / CXXC1 (18q21.1)MRS2 (6p22.3) / FAM65B (6p22.3)
MRS2 (6p22.3) / HMGB1 (13q12.3)LRRC16A 6p22.2 / MRS2 6p22.3MRS2 6p22.3 / FAM65B 6p22.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MRS2   13785
Cards
Entrez_Gene (NCBI)MRS2  57380  magnesium transporter MRS2
AliasesHPT; MRS2L
GeneCards (Weizmann)MRS2
Ensembl hg19 (Hinxton)ENSG00000124532 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124532 [Gene_View]  ENSG00000124532 [Sequence]  chr6:24402908-24426194 [Contig_View]  MRS2 [Vega]
ICGC DataPortalENSG00000124532
TCGA cBioPortalMRS2
AceView (NCBI)MRS2
Genatlas (Paris)MRS2
WikiGenes57380
SOURCE (Princeton)MRS2
Genetics Home Reference (NIH)MRS2
Genomic and cartography
GoldenPath hg38 (UCSC)MRS2  -     chr6:24402908-24426194 +  6p22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRS2  -     6p22.3   [Description]    (hg19-Feb_2009)
EnsemblMRS2 - 6p22.3 [CytoView hg19]  MRS2 - 6p22.3 [CytoView hg38]
Mapping of homologs : NCBIMRS2 [Mapview hg19]  MRS2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA828962 AA836333 AF052167 AF288288 AF293076
RefSeq transcript (Entrez)NM_001286264 NM_001286265 NM_001286266 NM_020662
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRS2
Cluster EST : UnigeneHs.732395 [ NCBI ]
CGAP (NCI)Hs.732395
Alternative Splicing GalleryENSG00000124532
Gene ExpressionMRS2 [ NCBI-GEO ]   MRS2 [ EBI - ARRAY_EXPRESS ]   MRS2 [ SEEK ]   MRS2 [ MEM ]
Gene Expression Viewer (FireBrowse)MRS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57380
GTEX Portal (Tissue expression)MRS2
Human Protein AtlasENSG00000124532-MRS2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HD23   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HD23  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HD23
Splice isoforms : SwissVarQ9HD23
PhosPhoSitePlusQ9HD23
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)MRS2
DMDM Disease mutations57380
Blocks (Seattle)MRS2
SuperfamilyQ9HD23
Human Protein Atlas [tissue]ENSG00000124532-MRS2 [tissue]
Peptide AtlasQ9HD23
HPRD17603
IPIIPI00941475   IPI00646426   IPI00031487   IPI01015288   IPI00010188   IPI01015703   IPI00646903   
Protein Interaction databases
DIP (DOE-UCLA)Q9HD23
IntAct (EBI)Q9HD23
FunCoupENSG00000124532
BioGRIDMRS2
STRING (EMBL)MRS2
ZODIACMRS2
Ontologies - Pathways
QuickGOQ9HD23
Ontology : AmiGOmitochondrion  mitochondrial inner membrane  mitochondrial inner membrane  magnesium ion transmembrane transporter activity  magnesium ion transmembrane transporter activity  magnesium ion transmembrane transporter activity  magnesium ion transport  integral component of membrane  mitochondrial magnesium ion transmembrane transport  mitochondrial magnesium ion transmembrane transport  transmembrane transport  
Ontology : EGO-EBImitochondrion  mitochondrial inner membrane  mitochondrial inner membrane  magnesium ion transmembrane transporter activity  magnesium ion transmembrane transporter activity  magnesium ion transmembrane transporter activity  magnesium ion transport  integral component of membrane  mitochondrial magnesium ion transmembrane transport  mitochondrial magnesium ion transmembrane transport  transmembrane transport  
NDEx NetworkMRS2
Atlas of Cancer Signalling NetworkMRS2
Wikipedia pathwaysMRS2
Orthology - Evolution
OrthoDB57380
GeneTree (enSembl)ENSG00000124532
Phylogenetic Trees/Animal Genes : TreeFamMRS2
HOVERGENQ9HD23
HOGENOMQ9HD23
Homologs : HomoloGeneMRS2
Homology/Alignments : Family Browser (UCSC)MRS2
Gene fusions - Rearrangements
Fusion : MitelmanLRRC16A/MRS2 [6p22.2/6p22.3]  [t(6;6)(p22;p22)]  
Fusion : MitelmanMRS2/FAM65B [6p22.3/6p22.3]  [t(6;6)(p22;p22)]  
Fusion PortalLRRC16A 6p22.2 MRS2 6p22.3 BRCA
Fusion PortalMRS2 6p22.3 FAM65B 6p22.3 BRCA
Fusion : QuiverMRS2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRS2
dbVarMRS2
ClinVarMRS2
1000_GenomesMRS2 
Exome Variant ServerMRS2
ExAC (Exome Aggregation Consortium)ENSG00000124532
GNOMAD BrowserENSG00000124532
Varsome BrowserMRS2
Genetic variants : HAPMAP57380
Genomic Variants (DGV)MRS2 [DGVbeta]
DECIPHERMRS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRS2 
Mutations
ICGC Data PortalMRS2 
TCGA Data PortalMRS2 
Broad Tumor PortalMRS2
OASIS PortalMRS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMRS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MRS2
DgiDB (Drug Gene Interaction Database)MRS2
DoCM (Curated mutations)MRS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRS2 (select a term)
intoGenMRS2
Cancer3DMRS2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETMRS2
MedgenMRS2
Genetic Testing Registry MRS2
NextProtQ9HD23 [Medical]
TSGene57380
GENETestsMRS2
Target ValidationMRS2
Huge Navigator MRS2 [HugePedia]
snp3D : Map Gene to Disease57380
BioCentury BCIQMRS2
ClinGenMRS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57380
Chemical/Pharm GKB GenePA162396189
Clinical trialMRS2
Miscellaneous
canSAR (ICR)MRS2 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRS2
EVEXMRS2
GoPubMedMRS2
iHOPMRS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:23:54 CET 2018

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