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MRTFB (myocardin related transcription factor B)

Identity

Alias_namesMKL2
MKL/myocardin like 2
MKL and myocardin family member 2
MKL1/myocardin like 2
Alias_symbol (synonym)MRTF-B
FLJ31823
Other aliasNPD001
HGNC (Hugo) MRTFB
LocusID (NCBI) 57496
Atlas_Id 57410
Location 16p13.12  [Link to chromosome band 16p13]
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)MRTFB   29819
Cards
Entrez_Gene (NCBI)MRTFB  57496  myocardin related transcription factor B
AliasesMKL2; MRTF-B; NPD001
GeneCards (Weizmann)MRTFB
Ensembl hg19 (Hinxton)ENSG00000186260 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186260 [Gene_View]  ENSG00000186260 [Sequence]  - [Contig_View]  MRTFB [Vega]
ICGC DataPortalENSG00000186260
TCGA cBioPortalMRTFB
AceView (NCBI)MRTFB
Genatlas (Paris)MRTFB
WikiGenes57496
SOURCE (Princeton)MRTFB
Genetics Home Reference (NIH)MRTFB
Genomic and cartography
GoldenPath hg38 (UCSC)MRTFB  -  
GoldenPath hg19 (UCSC)MRTFB  -  
GoldenPathMRTFB - [CytoView hg19]  MRTFB - [CytoView hg38]
ImmunoBaseENSG00000186260
Mapping of homologs : NCBIMRTFB [Mapview hg19]  MRTFB [Mapview hg38]
OMIM609463   
Gene and transcription
Genbank (Entrez)AB033069 AF078853 AI498641 AK056385 AK057216
RefSeq transcript (Entrez)NM_001308142 NM_001365411 NM_001365412 NM_001365413 NM_001365414 NM_001365415 NM_001365416 NM_001365417 NM_001365418 NM_001365419 NM_001365420 NM_001365421 NM_014048
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRTFB
Cluster EST : UnigeneHs.683854 [ NCBI ]
CGAP (NCI)Hs.683854
Alternative Splicing GalleryENSG00000186260
Gene ExpressionMRTFB [ NCBI-GEO ]   MRTFB [ EBI - ARRAY_EXPRESS ]   MRTFB [ SEEK ]   MRTFB [ MEM ]
Gene Expression Viewer (FireBrowse)MRTFB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57496
GTEX Portal (Tissue expression)MRTFB
Human Protein AtlasENSG00000186260-MRTFB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULH7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULH7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULH7
Splice isoforms : SwissVarQ9ULH7
PhosPhoSitePlusQ9ULH7
Domaine pattern : Prosite (Expaxy)RPEL (PS51073)    SAP (PS50800)   
Domains : Interpro (EBI)RPEL_repeat    SAP_dom    SAP_dom_sf   
Domain families : Pfam (Sanger)RPEL (PF02755)    SAP (PF02037)   
Domain families : Pfam (NCBI)pfam02755    pfam02037   
Domain families : Smart (EMBL)RPEL (SM00707)  SAP (SM00513)  
Conserved Domain (NCBI)MRTFB
DMDM Disease mutations57496
Blocks (Seattle)MRTFB
SuperfamilyQ9ULH7
Human Protein Atlas [tissue]ENSG00000186260-MRTFB [tissue]
Peptide AtlasQ9ULH7
IPIIPI00329152   IPI00335643   IPI00418489   IPI00335641   IPI00022318   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULH7
IntAct (EBI)Q9ULH7
FunCoupENSG00000186260
BioGRIDMRTFB
STRING (EMBL)MRTFB
ZODIACMRTFB
Ontologies - Pathways
QuickGOQ9ULH7
Ontology : AmiGOtranscription coactivator activity  protein binding  nucleus  muscle organ development  cadherin binding  positive regulation of striated muscle tissue development  positive regulation of transcription by RNA polymerase II  smooth muscle cell differentiation  
Ontology : EGO-EBItranscription coactivator activity  protein binding  nucleus  muscle organ development  cadherin binding  positive regulation of striated muscle tissue development  positive regulation of transcription by RNA polymerase II  smooth muscle cell differentiation  
NDEx NetworkMRTFB
Atlas of Cancer Signalling NetworkMRTFB
Wikipedia pathwaysMRTFB
Orthology - Evolution
OrthoDB57496
GeneTree (enSembl)ENSG00000186260
Phylogenetic Trees/Animal Genes : TreeFamMRTFB
HOGENOMQ9ULH7
Homologs : HomoloGeneMRTFB
Homology/Alignments : Family Browser (UCSC)MRTFB
Gene fusions - Rearrangements
Fusion : QuiverMRTFB
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRTFB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRTFB
dbVarMRTFB
ClinVarMRTFB
1000_GenomesMRTFB 
Exome Variant ServerMRTFB
ExAC (Exome Aggregation Consortium)ENSG00000186260
GNOMAD BrowserENSG00000186260
Varsome BrowserMRTFB
Genetic variants : HAPMAP57496
Genomic Variants (DGV)MRTFB [DGVbeta]
DECIPHERMRTFB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRTFB 
Mutations
ICGC Data PortalMRTFB 
TCGA Data PortalMRTFB 
Broad Tumor PortalMRTFB
OASIS PortalMRTFB [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMRTFB
BioMutasearch MRTFB
DgiDB (Drug Gene Interaction Database)MRTFB
DoCM (Curated mutations)MRTFB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRTFB (select a term)
intoGenMRTFB
Cancer3DMRTFB(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609463   
Orphanet
DisGeNETMRTFB
MedgenMRTFB
Genetic Testing Registry MRTFB
NextProtQ9ULH7 [Medical]
TSGene57496
GENETestsMRTFB
Target ValidationMRTFB
Huge Navigator MRTFB [HugePedia]
snp3D : Map Gene to Disease57496
BioCentury BCIQMRTFB
ClinGenMRTFB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57496
Chemical/Pharm GKB GenePA134981329
Clinical trialMRTFB
Miscellaneous
canSAR (ICR)MRTFB (select the gene name)
DataMed IndexMRTFB
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRTFB
EVEXMRTFB
GoPubMedMRTFB
iHOPMRTFB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 26 18:19:29 CEST 2019

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