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MRVI1 (murine retrovirus integration site 1 homolog)

Identity

Alias_symbol (synonym)JAW1L
IRAG
Other alias
HGNC (Hugo) MRVI1
LocusID (NCBI) 10335
Atlas_Id 41431
Location 11p15.4  [Link to chromosome band 11p15]
Location_base_pair Starts at 10573091 and ends at 10652301 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BCR (22q11.23) / MRVI1 (11p15.4)SBF2 (11p15.4) / MRVI1 (11p15.4)BCR 22q11.23 / MRVI1 11p15.4
SBF2 11p15.4 / MRVI1 11p15.4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MRVI1   7237
Cards
Entrez_Gene (NCBI)MRVI1  10335  murine retrovirus integration site 1 homolog
AliasesIRAG; JAW1L
GeneCards (Weizmann)MRVI1
Ensembl hg19 (Hinxton)ENSG00000072952 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000072952 [Gene_View]  chr11:10573091-10652301 [Contig_View]  MRVI1 [Vega]
ICGC DataPortalENSG00000072952
TCGA cBioPortalMRVI1
AceView (NCBI)MRVI1
Genatlas (Paris)MRVI1
WikiGenes10335
SOURCE (Princeton)MRVI1
Genetics Home Reference (NIH)MRVI1
Genomic and cartography
GoldenPath hg38 (UCSC)MRVI1  -     chr11:10573091-10652301 -  11p15.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRVI1  -     11p15.4   [Description]    (hg19-Feb_2009)
EnsemblMRVI1 - 11p15.4 [CytoView hg19]  MRVI1 - 11p15.4 [CytoView hg38]
Mapping of homologs : NCBIMRVI1 [Mapview hg19]  MRVI1 [Mapview hg38]
OMIM604673   
Gene and transcription
Genbank (Entrez)AF081249 AF081250 AK002039 AK127209 AK296336
RefSeq transcript (Entrez)NM_001098579 NM_001100163 NM_001100167 NM_001206880 NM_001206881 NM_130385
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRVI1
Cluster EST : UnigeneHs.680194 [ NCBI ]
CGAP (NCI)Hs.680194
Alternative Splicing GalleryENSG00000072952
Gene ExpressionMRVI1 [ NCBI-GEO ]   MRVI1 [ EBI - ARRAY_EXPRESS ]   MRVI1 [ SEEK ]   MRVI1 [ MEM ]
Gene Expression Viewer (FireBrowse)MRVI1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10335
GTEX Portal (Tissue expression)MRVI1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6F6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6F6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6F6
Splice isoforms : SwissVarQ9Y6F6
PhosPhoSitePlusQ9Y6F6
Domains : Interpro (EBI)MRVI1   
Domain families : Pfam (Sanger)MRVI1 (PF05781)   
Domain families : Pfam (NCBI)pfam05781   
Conserved Domain (NCBI)MRVI1
DMDM Disease mutations10335
Blocks (Seattle)MRVI1
SuperfamilyQ9Y6F6
Human Protein AtlasENSG00000072952
Peptide AtlasQ9Y6F6
HPRD05242
IPIIPI00940764   IPI00295313   IPI00973721   IPI01018664   IPI00867598   IPI00985272   IPI00921916   IPI00978657   IPI01010819   IPI01018689   IPI00983996   IPI00981657   IPI00981130   IPI00922700   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6F6
IntAct (EBI)Q9Y6F6
FunCoupENSG00000072952
BioGRIDMRVI1
STRING (EMBL)MRVI1
ZODIACMRVI1
Ontologies - Pathways
QuickGOQ9Y6F6
Ontology : AmiGOprotein binding  endoplasmic reticulum membrane  integral component of membrane  sarcoplasmic reticulum  platelet dense tubular network membrane  perinuclear region of cytoplasm  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum membrane  integral component of membrane  sarcoplasmic reticulum  platelet dense tubular network membrane  perinuclear region of cytoplasm  
Pathways : KEGGVascular smooth muscle contraction   
NDEx NetworkMRVI1
Atlas of Cancer Signalling NetworkMRVI1
Wikipedia pathwaysMRVI1
Orthology - Evolution
OrthoDB10335
GeneTree (enSembl)ENSG00000072952
Phylogenetic Trees/Animal Genes : TreeFamMRVI1
HOVERGENQ9Y6F6
HOGENOMQ9Y6F6
Homologs : HomoloGeneMRVI1
Homology/Alignments : Family Browser (UCSC)MRVI1
Gene fusions - Rearrangements
Fusion : MitelmanBCR/MRVI1 [22q11.23/11p15.4]  [t(11;22)(p15;q11)]  
Fusion : MitelmanSBF2/MRVI1 [11p15.4/11p15.4]  [t(11;11)(p15;p15)]  
Fusion: TCGABCR 22q11.23 MRVI1 11p15.4 BRCA
Fusion: TCGASBF2 11p15.4 MRVI1 11p15.4 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRVI1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRVI1
dbVarMRVI1
ClinVarMRVI1
1000_GenomesMRVI1 
Exome Variant ServerMRVI1
ExAC (Exome Aggregation Consortium)MRVI1 (select the gene name)
Genetic variants : HAPMAP10335
Genomic Variants (DGV)MRVI1 [DGVbeta]
DECIPHERMRVI1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRVI1 
Mutations
ICGC Data PortalMRVI1 
TCGA Data PortalMRVI1 
Broad Tumor PortalMRVI1
OASIS PortalMRVI1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRVI1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMRVI1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MRVI1
DgiDB (Drug Gene Interaction Database)MRVI1
DoCM (Curated mutations)MRVI1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRVI1 (select a term)
intoGenMRVI1
Cancer3DMRVI1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604673   
Orphanet
MedgenMRVI1
Genetic Testing Registry MRVI1
NextProtQ9Y6F6 [Medical]
TSGene10335
GENETestsMRVI1
Target ValidationMRVI1
Huge Navigator MRVI1 [HugePedia]
snp3D : Map Gene to Disease10335
BioCentury BCIQMRVI1
ClinGenMRVI1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10335
Chemical/Pharm GKB GenePA31032
Clinical trialMRVI1
Miscellaneous
canSAR (ICR)MRVI1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRVI1
EVEXMRVI1
GoPubMedMRVI1
iHOPMRVI1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:45:24 CEST 2017

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