Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MS4A2 (membrane spanning 4-domains A2)

Identity

Alias_namesFCER1B
IGER
APY
IgE responsiveness (atopic)
membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)
membrane-spanning 4-domains, subfamily A, member 2
Alias_symbol (synonym)MS4A1
Other aliasATOPY
FCERI
IGEL
IGHER
HGNC (Hugo) MS4A2
LocusID (NCBI) 2206
Atlas_Id 70504
Location 11q12.1  [Link to chromosome band 11q12]
Location_base_pair Starts at 60088664 and ends at 60098467 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MS4A2   7316
Cards
Entrez_Gene (NCBI)MS4A2  2206  membrane spanning 4-domains A2
AliasesAPY; ATOPY; FCER1B; FCERI; 
IGEL; IGER; IGHER; MS4A1
GeneCards (Weizmann)MS4A2
Ensembl hg19 (Hinxton)ENSG00000149534 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149534 [Gene_View]  chr11:60088664-60098467 [Contig_View]  MS4A2 [Vega]
ICGC DataPortalENSG00000149534
TCGA cBioPortalMS4A2
AceView (NCBI)MS4A2
Genatlas (Paris)MS4A2
WikiGenes2206
SOURCE (Princeton)MS4A2
Genetics Home Reference (NIH)MS4A2
Genomic and cartography
GoldenPath hg38 (UCSC)MS4A2  -     chr11:60088664-60098467 +  11q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MS4A2  -     11q12.1   [Description]    (hg19-Feb_2009)
EnsemblMS4A2 - 11q12.1 [CytoView hg19]  MS4A2 - 11q12.1 [CytoView hg38]
Mapping of homologs : NCBIMS4A2 [Mapview hg19]  MS4A2 [Mapview hg38]
OMIM147050   147138   
Gene and transcription
Genbank (Entrez)AK304487 AK310142 BC074800 BC074843 D10583
RefSeq transcript (Entrez)NM_000139 NM_001142303 NM_001256916
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MS4A2
Cluster EST : UnigeneHs.386748 [ NCBI ]
CGAP (NCI)Hs.386748
Alternative Splicing GalleryENSG00000149534
Gene ExpressionMS4A2 [ NCBI-GEO ]   MS4A2 [ EBI - ARRAY_EXPRESS ]   MS4A2 [ SEEK ]   MS4A2 [ MEM ]
Gene Expression Viewer (FireBrowse)MS4A2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2206
GTEX Portal (Tissue expression)MS4A2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ01362   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ01362  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ01362
Splice isoforms : SwissVarQ01362
PhosPhoSitePlusQ01362
Domains : Interpro (EBI)CD20-like    MS4A    MS4A2   
Domain families : Pfam (Sanger)CD20 (PF04103)   
Domain families : Pfam (NCBI)pfam04103   
Conserved Domain (NCBI)MS4A2
DMDM Disease mutations2206
Blocks (Seattle)MS4A2
SuperfamilyQ01362
Human Protein AtlasENSG00000149534
Peptide AtlasQ01362
HPRD00915
IPIIPI00007153   IPI00915397   
Protein Interaction databases
DIP (DOE-UCLA)Q01362
IntAct (EBI)Q01362
FunCoupENSG00000149534
BioGRIDMS4A2
STRING (EMBL)MS4A2
ZODIACMS4A2
Ontologies - Pathways
QuickGOQ01362
Ontology : AmiGOplasma membrane  integral component of plasma membrane  inflammatory response  immune response  external side of plasma membrane  IgE binding  Fc-epsilon receptor I complex  Fc-epsilon receptor signaling pathway  
Ontology : EGO-EBIplasma membrane  integral component of plasma membrane  inflammatory response  immune response  external side of plasma membrane  IgE binding  Fc-epsilon receptor I complex  Fc-epsilon receptor signaling pathway  
Pathways : BIOCARTAFc Epsilon Receptor I Signaling in Mast Cells [Genes]   
Pathways : KEGGFc epsilon RI signaling pathway    Asthma   
NDEx NetworkMS4A2
Atlas of Cancer Signalling NetworkMS4A2
Wikipedia pathwaysMS4A2
Orthology - Evolution
OrthoDB2206
GeneTree (enSembl)ENSG00000149534
Phylogenetic Trees/Animal Genes : TreeFamMS4A2
HOVERGENQ01362
HOGENOMQ01362
Homologs : HomoloGeneMS4A2
Homology/Alignments : Family Browser (UCSC)MS4A2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMS4A2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MS4A2
dbVarMS4A2
ClinVarMS4A2
1000_GenomesMS4A2 
Exome Variant ServerMS4A2
ExAC (Exome Aggregation Consortium)MS4A2 (select the gene name)
Genetic variants : HAPMAP2206
Genomic Variants (DGV)MS4A2 [DGVbeta]
DECIPHERMS4A2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMS4A2 
Mutations
ICGC Data PortalMS4A2 
TCGA Data PortalMS4A2 
Broad Tumor PortalMS4A2
OASIS PortalMS4A2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMS4A2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMS4A2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MS4A2
DgiDB (Drug Gene Interaction Database)MS4A2
DoCM (Curated mutations)MS4A2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MS4A2 (select a term)
intoGenMS4A2
Cancer3DMS4A2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147050    147138   
Orphanet
MedgenMS4A2
Genetic Testing Registry MS4A2
NextProtQ01362 [Medical]
TSGene2206
GENETestsMS4A2
Target ValidationMS4A2
Huge Navigator MS4A2 [HugePedia]
snp3D : Map Gene to Disease2206
BioCentury BCIQMS4A2
ClinGenMS4A2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2206
Chemical/Pharm GKB GenePA31109
Clinical trialMS4A2
Miscellaneous
canSAR (ICR)MS4A2 (select the gene name)
Probes
Litterature
PubMed107 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMS4A2
EVEXMS4A2
GoPubMedMS4A2
iHOPMS4A2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 16:33:02 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.