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MS4A3 (membrane spanning 4-domains A3)

Identity

Alias (NCBI)CD20L
HTM4
HGNC (Hugo) MS4A3
HGNC Alias symbHTM4
HGNC Previous nameCD20L
HGNC Previous namemembrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
LocusID (NCBI) 932
Atlas_Id 52250
Location 11q12.1  [Link to chromosome band 11q12]
Location_base_pair Starts at 60056665 and ends at 60071115 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARNT2 (15q25.1)::MS4A3 (11q12.1)ARNT2 15q25.1::MS4A3 11q12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MS4A3   7317
Cards
Entrez_Gene (NCBI)MS4A3    membrane spanning 4-domains A3
AliasesCD20L; HTM4
GeneCards (Weizmann)MS4A3
Ensembl hg19 (Hinxton)ENSG00000149516 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149516 [Gene_View]  ENSG00000149516 [Sequence]  chr11:60056665-60071115 [Contig_View]  MS4A3 [Vega]
ICGC DataPortalENSG00000149516
TCGA cBioPortalMS4A3
AceView (NCBI)MS4A3
Genatlas (Paris)MS4A3
SOURCE (Princeton)MS4A3
Genetics Home Reference (NIH)MS4A3
Genomic and cartography
GoldenPath hg38 (UCSC)MS4A3  -     chr11:60056665-60071115 +  11q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MS4A3  -     11q12.1   [Description]    (hg19-Feb_2009)
GoldenPathMS4A3 - 11q12.1 [CytoView hg19]  MS4A3 - 11q12.1 [CytoView hg38]
ImmunoBaseENSG00000149516
Genome Data Viewer NCBIMS4A3 [Mapview hg19]  
OMIM606498   
Gene and transcription
Genbank (Entrez)AL601630 AY095480 BC008487 BE564041 BF210971
RefSeq transcript (Entrez)NM_001031666 NM_001031809 NM_006138
Consensus coding sequences : CCDS (NCBI)MS4A3
Gene ExpressionMS4A3 [ NCBI-GEO ]   MS4A3 [ EBI - ARRAY_EXPRESS ]   MS4A3 [ SEEK ]   MS4A3 [ MEM ]
Gene Expression Viewer (FireBrowse)MS4A3 [ Firebrowse - Broad ]
GenevisibleExpression of MS4A3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)932
GTEX Portal (Tissue expression)MS4A3
Human Protein AtlasENSG00000149516-MS4A3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96HJ5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96HJ5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96HJ5
PhosPhoSitePlusQ96HJ5
Domains : Interpro (EBI)CD20-like    MS4A    MS4A3   
Domain families : Pfam (Sanger)CD20 (PF04103)   
Domain families : Pfam (NCBI)pfam04103   
Conserved Domain (NCBI)MS4A3
SuperfamilyQ96HJ5
AlphaFold pdb e-kbQ96HJ5   
Human Protein Atlas [tissue]ENSG00000149516-MS4A3 [tissue]
HPRD09403
Protein Interaction databases
DIP (DOE-UCLA)Q96HJ5
IntAct (EBI)Q96HJ5
BioGRIDMS4A3
STRING (EMBL)MS4A3
ZODIACMS4A3
Ontologies - Pathways
QuickGOQ96HJ5
Ontology : AmiGOprotein binding  plasma membrane  plasma membrane  cell surface receptor signaling pathway  integral component of membrane  specific granule membrane  perinuclear region of cytoplasm  regulation of cell cycle  
Ontology : EGO-EBIprotein binding  plasma membrane  plasma membrane  cell surface receptor signaling pathway  integral component of membrane  specific granule membrane  perinuclear region of cytoplasm  regulation of cell cycle  
NDEx NetworkMS4A3
Atlas of Cancer Signalling NetworkMS4A3
Wikipedia pathwaysMS4A3
Orthology - Evolution
OrthoDB932
GeneTree (enSembl)ENSG00000149516
Phylogenetic Trees/Animal Genes : TreeFamMS4A3
Homologs : HomoloGeneMS4A3
Homology/Alignments : Family Browser (UCSC)MS4A3
Gene fusions - Rearrangements
Fusion : MitelmanARNT2::MS4A3 [15q25.1/11q12.1]  
Fusion : QuiverMS4A3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMS4A3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MS4A3
dbVarMS4A3
ClinVarMS4A3
MonarchMS4A3
1000_GenomesMS4A3 
Exome Variant ServerMS4A3
GNOMAD BrowserENSG00000149516
Varsome BrowserMS4A3
ACMGMS4A3 variants
VarityQ96HJ5
Genomic Variants (DGV)MS4A3 [DGVbeta]
DECIPHERMS4A3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMS4A3 
Mutations
ICGC Data PortalMS4A3 
TCGA Data PortalMS4A3 
Broad Tumor PortalMS4A3
OASIS PortalMS4A3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMS4A3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMS4A3
Mutations and Diseases : HGMDMS4A3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMS4A3
DgiDB (Drug Gene Interaction Database)MS4A3
DoCM (Curated mutations)MS4A3
CIViC (Clinical Interpretations of Variants in Cancer)MS4A3
Cancer3DMS4A3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606498   
Orphanet
DisGeNETMS4A3
MedgenMS4A3
Genetic Testing Registry MS4A3
NextProtQ96HJ5 [Medical]
GENETestsMS4A3
Target ValidationMS4A3
Huge Navigator MS4A3 [HugePedia]
ClinGenMS4A3
Clinical trials, drugs, therapy
MyCancerGenomeMS4A3
Protein Interactions : CTDMS4A3
Pharm GKB GenePA31112
PharosQ96HJ5
Clinical trialMS4A3
Miscellaneous
canSAR (ICR)MS4A3
HarmonizomeMS4A3
ARCHS4MS4A3
DataMed IndexMS4A3
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMS4A3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Jan 20 12:47:50 CET 2022

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