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MS4A6A (membrane spanning 4-domains A6A)

Identity

Alias_namesMS4A6
membrane-spanning 4-domains, subfamily A, member 6A
Alias_symbol (synonym)CD20L3
Other alias4SPAN3
4SPAN3.2
CDA01
MST090
MSTP090
HGNC (Hugo) MS4A6A
LocusID (NCBI) 64231
Atlas_Id 70508
Location 11q12.2  [Link to chromosome band 11q12]
Location_base_pair Starts at 60172498 and ends at 60184666 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BCAT2 (19q13.33) / MS4A6A (11q12.2)HSP90AA1 (14q32.31) / MS4A6A (11q12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MS4A6A   13375
Cards
Entrez_Gene (NCBI)MS4A6A  64231  membrane spanning 4-domains A6A
Aliases4SPAN3; 4SPAN3.2; CD20L3; CDA01; 
MS4A6; MST090; MSTP090
GeneCards (Weizmann)MS4A6A
Ensembl hg19 (Hinxton)ENSG00000110077 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000110077 [Gene_View]  ENSG00000110077 [Sequence]  chr11:60172498-60184666 [Contig_View]  MS4A6A [Vega]
ICGC DataPortalENSG00000110077
TCGA cBioPortalMS4A6A
AceView (NCBI)MS4A6A
Genatlas (Paris)MS4A6A
WikiGenes64231
SOURCE (Princeton)MS4A6A
Genetics Home Reference (NIH)MS4A6A
Genomic and cartography
GoldenPath hg38 (UCSC)MS4A6A  -     chr11:60172498-60184666 -  11q12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MS4A6A  -     11q12.2   [Description]    (hg19-Feb_2009)
EnsemblMS4A6A - 11q12.2 [CytoView hg19]  MS4A6A - 11q12.2 [CytoView hg38]
Mapping of homologs : NCBIMS4A6A [Mapview hg19]  MS4A6A [Mapview hg38]
OMIM606548   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001247999 NM_001330275 NM_022349 NM_152851 NM_152852
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MS4A6A
Cluster EST : UnigeneHs.744932 [ NCBI ]
CGAP (NCI)Hs.744932
Alternative Splicing GalleryENSG00000110077
Gene ExpressionMS4A6A [ NCBI-GEO ]   MS4A6A [ EBI - ARRAY_EXPRESS ]   MS4A6A [ SEEK ]   MS4A6A [ MEM ]
Gene Expression Viewer (FireBrowse)MS4A6A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64231
GTEX Portal (Tissue expression)MS4A6A
Human Protein AtlasENSG00000110077-MS4A6A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H2W1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H2W1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H2W1
Splice isoforms : SwissVarQ9H2W1
PhosPhoSitePlusQ9H2W1
Domains : Interpro (EBI)CD20-like    MS4A    MS4A6A/MS4A6E   
Domain families : Pfam (Sanger)CD20 (PF04103)   
Domain families : Pfam (NCBI)pfam04103   
Conserved Domain (NCBI)MS4A6A
DMDM Disease mutations64231
Blocks (Seattle)MS4A6A
SuperfamilyQ9H2W1
Human Protein Atlas [tissue]ENSG00000110077-MS4A6A [tissue]
Peptide AtlasQ9H2W1
HPRD09414
IPIIPI00295531   IPI00979397   IPI00027556   IPI00385096   IPI00909105   IPI00983784   IPI00984985   IPI00295532   IPI00976701   IPI00978323   IPI00979105   IPI00979881   IPI00978076   
Protein Interaction databases
DIP (DOE-UCLA)Q9H2W1
IntAct (EBI)Q9H2W1
FunCoupENSG00000110077
BioGRIDMS4A6A
STRING (EMBL)MS4A6A
ZODIACMS4A6A
Ontologies - Pathways
QuickGOQ9H2W1
Ontology : AmiGOintegral component of membrane  
Ontology : EGO-EBIintegral component of membrane  
NDEx NetworkMS4A6A
Atlas of Cancer Signalling NetworkMS4A6A
Wikipedia pathwaysMS4A6A
Orthology - Evolution
OrthoDB64231
GeneTree (enSembl)ENSG00000110077
Phylogenetic Trees/Animal Genes : TreeFamMS4A6A
HOVERGENQ9H2W1
HOGENOMQ9H2W1
Homologs : HomoloGeneMS4A6A
Homology/Alignments : Family Browser (UCSC)MS4A6A
Gene fusions - Rearrangements
Fusion : QuiverMS4A6A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMS4A6A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MS4A6A
dbVarMS4A6A
ClinVarMS4A6A
1000_GenomesMS4A6A 
Exome Variant ServerMS4A6A
ExAC (Exome Aggregation Consortium)ENSG00000110077
GNOMAD BrowserENSG00000110077
Varsome BrowserMS4A6A
Genetic variants : HAPMAP64231
Genomic Variants (DGV)MS4A6A [DGVbeta]
DECIPHERMS4A6A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMS4A6A 
Mutations
ICGC Data PortalMS4A6A 
TCGA Data PortalMS4A6A 
Broad Tumor PortalMS4A6A
OASIS PortalMS4A6A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMS4A6A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMS4A6A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MS4A6A
DgiDB (Drug Gene Interaction Database)MS4A6A
DoCM (Curated mutations)MS4A6A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MS4A6A (select a term)
intoGenMS4A6A
Cancer3DMS4A6A(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606548   
Orphanet
DisGeNETMS4A6A
MedgenMS4A6A
Genetic Testing Registry MS4A6A
NextProtQ9H2W1 [Medical]
TSGene64231
GENETestsMS4A6A
Target ValidationMS4A6A
Huge Navigator MS4A6A [HugePedia]
snp3D : Map Gene to Disease64231
BioCentury BCIQMS4A6A
ClinGenMS4A6A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64231
Chemical/Pharm GKB GenePA31119
Clinical trialMS4A6A
Miscellaneous
canSAR (ICR)MS4A6A (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMS4A6A
EVEXMS4A6A
GoPubMedMS4A6A
iHOPMS4A6A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:18:45 CEST 2018
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