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MSH4 (mutS homolog 4 (E. coli))

Identity

Other names-
HGNC (Hugo) MSH4
LocusID (NCBI) 4438
Location 1p31.1
Location_base_pair Starts at 76262556 and ends at 76378923 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MSH4   7327
Entrez_Gene (NCBI)MSH4  4438  mutS homolog 4 (E. coli)
Cards
GeneCards (Weizmann)MSH4
Ensembl (Hinxton)ENSG00000057468 [Gene_View]  chr1:76262556-76378923 [Contig_View]  MSH4 [Vega]
AceView (NCBI)MSH4
Genatlas (Paris)MSH4
SOURCE (Stanford)NM_002440
Genomic and cartography
GoldenPath (UCSC)MSH4  -  1p31.1   chr1:76262556-76378923 +  1p31.1   [Description]    (hg19-Feb_2009)
EnsemblMSH4 - 1p31.1 [CytoView]
Mapping of homologs : NCBIMSH4 [Mapview]
OMIM602105   
Gene and transcription
Genbank (Entrez)AF104243 AJ844635 BC033030 DB077677 DQ891259
RefSeq transcript (SRS)NM_002440
RefSeq transcript (Entrez)NM_002440
RefSeq genomic (SRS)AC_000133 NC_000001 NC_018912 NG_029861 NT_032977 NW_001838579 NW_004077990
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NG_029861 NT_032977 NW_001838579 NW_004077990
Consensus coding sequences : CCDS (NCBI)MSH4
Cluster EST : UnigeneHs.216639 [ SRS ] Hs.216639 [ NCBI ]
CGAP (NCI)Hs.216639
Alternative Splicing : Fast-db (Paris)GSHG0033102
Alternative Splicing GalleryENSG00000057468
Gene ExpressionMSH4 [ NCBI-GEO ]   MSH4 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15457 (SRS) O15457 (Uniprot)
NextProtO15457
With graphics : InterProO15457
Splice isoforms : SwissVarO15457(Swissvar)
Domaine pattern : Prosite (SRS)DNA_MISMATCH_REPAIR_2 (PS00486)   
Domaine pattern : Prosite (Expaxy)DNA_MISMATCH_REPAIR_2 (PS00486)   
Domains : Interpro (SRS)DNA_mismatch_repair_MutS_C    DNA_mismatch_repair_MutS_clamp    DNA_mismatch_repair_MutS_core    DNA_mmatch_repair_MutS_con_dom   
Domains : Interpro (EBI)DNA_mismatch_repair_MutS_C    DNA_mismatch_repair_MutS_clamp    DNA_mismatch_repair_MutS_core    DNA_mmatch_repair_MutS_con_dom   
Related proteins : CluSTrO15457
Domain families : Pfam (SRS)MutS_II (PF05188)    MutS_III (PF05192)    MutS_IV (PF05190)    MutS_V (PF00488)   
Domain families : Pfam (Sanger)MutS_II (PF05188)    MutS_III (PF05192)    MutS_IV (PF05190)    MutS_V (PF00488)   
Domain families : Pfam (NCBI)pfam05188    pfam05192    pfam05190    pfam00488   
Domain families : Smart (EMBL)MUTSac (SM00534)  MUTSd (SM00533)  
DMDM4438
Blocks (Seattle)O15457
Human Protein AtlasENSG00000057468
HPRD03658
IPIIPI00289914   
Protein Interaction databases
DIP (DOE-UCLA)O15457
IntAct (EBI)O15457
FunCoupENSG00000057468
REACTOMEMSH4
Protein Interaction Database4438
BioGRIDMSH4
InParanoidO15457
Interologous Interaction database O15457
IntegromeDBMSH4
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)MSH4
SNP (GeneSNP Utah)MSH4
SNP : HGBaseMSH4
Genetic variants : HAPMAPMSH4
Somatic Mutations in Cancer : COSMICMSH4 
CONAN: Copy Number AnalysisMSH4 
Mutations and Diseases : HGMDMSH4
OMIM602105   
GENETests602105   
Disease Genetic AssociationMSH4
Huge Navigator MSH4 [HugePedia]  MSH4 [HugeCancerGEM]
Genomic VariantsMSH4  MSH4 [DGVbeta]
ClinVarMSH4
snp3D : Map Gene to Disease4438
General knowledge
Homologs : HomoloGeneMSH4
Homology/Alignments : Family Browser (UCSC)MSH4
Phylogenetic Trees/Animal Genes : TreeFamMSH4
Chemical/Protein Interactions : CTD4438
Chemical/Pharm GKB GenePA31135
Clinical trialMSH4
Cancer Resource (Charite)ENSG00000057468
Ontology : AmiGOmeiotic mismatch repair  synaptonemal complex  ovarian follicle development  DNA binding  damaged DNA binding  ATP binding  nucleus  reciprocal meiotic recombination  spermatogenesis  female gamete generation  DNA-dependent ATPase activity  mismatched DNA binding  mismatch repair complex  homologous chromosome segregation  chiasma assembly  
Ontology : EGO-EBImeiotic mismatch repair  synaptonemal complex  ovarian follicle development  DNA binding  damaged DNA binding  ATP binding  nucleus  reciprocal meiotic recombination  spermatogenesis  female gamete generation  DNA-dependent ATPase activity  mismatched DNA binding  mismatch repair complex  homologous chromosome segregation  chiasma assembly  
Other databases
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
PubGeneMSH4
iHOPMSH4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:51:10 CEST 2013
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