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MSI1 (musashi RNA binding protein 1)

Identity

Alias_namesMusashi (Drosophila) homolog 1
musashi homolog 1 (Drosophila)
Other alias-
HGNC (Hugo) MSI1
LocusID (NCBI) 4440
Atlas_Id 41432
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 120341330 and ends at 120369180 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FAM222A (12q24.11) / MSI1 (12q24.31)GCN1 (12q24.23) / MSI1 (12q24.31)PXN (12q24.23) / MSI1 (12q24.31)
C12orf34 MSI1 12q24.31PXN 12q24.23 / MSI1 12q24.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MSI1   7330
Cards
Entrez_Gene (NCBI)MSI1  4440  musashi RNA binding protein 1
Aliases
GeneCards (Weizmann)MSI1
Ensembl hg19 (Hinxton)ENSG00000135097 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135097 [Gene_View]  chr12:120341330-120369180 [Contig_View]  MSI1 [Vega]
ICGC DataPortalENSG00000135097
TCGA cBioPortalMSI1
AceView (NCBI)MSI1
Genatlas (Paris)MSI1
WikiGenes4440
SOURCE (Princeton)MSI1
Genetics Home Reference (NIH)MSI1
Genomic and cartography
GoldenPath hg38 (UCSC)MSI1  -     chr12:120341330-120369180 -  12q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MSI1  -     12q24.31   [Description]    (hg19-Feb_2009)
EnsemblMSI1 - 12q24.31 [CytoView hg19]  MSI1 - 12q24.31 [CytoView hg38]
Mapping of homologs : NCBIMSI1 [Mapview hg19]  MSI1 [Mapview hg38]
OMIM603328   
Gene and transcription
Genbank (Entrez)AB012851 AB072590 AB072591 AB072592 AB073212
RefSeq transcript (Entrez)NM_002442
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MSI1
Cluster EST : UnigeneHs.158311 [ NCBI ]
CGAP (NCI)Hs.158311
Alternative Splicing GalleryENSG00000135097
Gene ExpressionMSI1 [ NCBI-GEO ]   MSI1 [ EBI - ARRAY_EXPRESS ]   MSI1 [ SEEK ]   MSI1 [ MEM ]
Gene Expression Viewer (FireBrowse)MSI1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4440
GTEX Portal (Tissue expression)MSI1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43347   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43347  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43347
Splice isoforms : SwissVarO43347
PhosPhoSitePlusO43347
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)MSI_RRM1    MSI_RRM2    Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)MSI1
DMDM Disease mutations4440
Blocks (Seattle)MSI1
SuperfamilyO43347
Human Protein AtlasENSG00000135097
Peptide AtlasO43347
HPRD04509
IPIIPI00001007   IPI01022011   
Protein Interaction databases
DIP (DOE-UCLA)O43347
IntAct (EBI)O43347
FunCoupENSG00000135097
BioGRIDMSI1
STRING (EMBL)MSI1
ZODIACMSI1
Ontologies - Pathways
QuickGOO43347
Ontology : AmiGORNA binding  nucleus  cytoplasm  polysome  nervous system development  poly(U) RNA binding  identical protein binding  
Ontology : EGO-EBIRNA binding  nucleus  cytoplasm  polysome  nervous system development  poly(U) RNA binding  identical protein binding  
Pathways : KEGGmRNA surveillance pathway   
NDEx NetworkMSI1
Atlas of Cancer Signalling NetworkMSI1
Wikipedia pathwaysMSI1
Orthology - Evolution
OrthoDB4440
GeneTree (enSembl)ENSG00000135097
Phylogenetic Trees/Animal Genes : TreeFamMSI1
HOVERGENO43347
HOGENOMO43347
Homologs : HomoloGeneMSI1
Homology/Alignments : Family Browser (UCSC)MSI1
Gene fusions - Rearrangements
Fusion : MitelmanFAM222A/MSI1 [12q24.11/12q24.31]  [t(12;12)(q24;q24)]  
Fusion : MitelmanGCN1L1/12q24.31 [MSI1/t(12;12)(q24;q24)]  
Fusion : MitelmanPXN/MSI1 [12q24.23/12q24.31]  [t(12;12)(q24;q24)]  
Fusion: TCGAC12orf34 MSI1 12q24.31 LUSC
Fusion: TCGAPXN 12q24.23 MSI1 12q24.31 HNSC LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMSI1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MSI1
dbVarMSI1
ClinVarMSI1
1000_GenomesMSI1 
Exome Variant ServerMSI1
ExAC (Exome Aggregation Consortium)MSI1 (select the gene name)
Genetic variants : HAPMAP4440
Genomic Variants (DGV)MSI1 [DGVbeta]
DECIPHERMSI1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMSI1 
Mutations
ICGC Data PortalMSI1 
TCGA Data PortalMSI1 
Broad Tumor PortalMSI1
OASIS PortalMSI1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMSI1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMSI1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MSI1
DgiDB (Drug Gene Interaction Database)MSI1
DoCM (Curated mutations)MSI1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MSI1 (select a term)
intoGenMSI1
Cancer3DMSI1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603328   
Orphanet
MedgenMSI1
Genetic Testing Registry MSI1
NextProtO43347 [Medical]
TSGene4440
GENETestsMSI1
Target ValidationMSI1
Huge Navigator MSI1 [HugePedia]
snp3D : Map Gene to Disease4440
BioCentury BCIQMSI1
ClinGenMSI1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4440
Chemical/Pharm GKB GenePA31137
Clinical trialMSI1
Miscellaneous
canSAR (ICR)MSI1 (select the gene name)
Probes
Litterature
PubMed70 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMSI1
EVEXMSI1
GoPubMedMSI1
iHOPMSI1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:45:25 CEST 2017

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