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MSL1 (male specific lethal 1 homolog)

Identity

Alias_namesmale-specific lethal 1 homolog (Drosophila)
Alias_symbol (synonym)hMSL1
MSL-1
DKFZp686P24239
Other alias
HGNC (Hugo) MSL1
LocusID (NCBI) 339287
Atlas_Id 51219
Location 17q21.1  [Link to chromosome band 17q21]
Location_base_pair Starts at 40122537 and ends at 40136791 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ITGA10 (1q21.1) / MSL1 (17q21.1)LOC646626 (1p22.3) / MSL1 (17q21.1)MSL1 (17q21.1) / CDK12 (17q12)
MSL1 (17q21.1) / MSL1 (17q21.1)MSL1 (17q21.1) / PPP3CA (4q24)MSL1 (17q21.1) / RBM28 (7q32.1)
RARA (17q21.2) / MSL1 (17q21.1)WIPF2 (17q21.1) / MSL1 (17q21.1)RARA 17q21.2 / MSL1 17q21.1
WIPF2 17q21.1 / MSL1 17q21.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MSL1   27905
Cards
Entrez_Gene (NCBI)MSL1  339287  male specific lethal 1 homolog
AliasesMSL-1; hMSL1
GeneCards (Weizmann)MSL1
Ensembl hg19 (Hinxton)ENSG00000188895 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188895 [Gene_View]  chr17:40122537-40136791 [Contig_View]  MSL1 [Vega]
ICGC DataPortalENSG00000188895
TCGA cBioPortalMSL1
AceView (NCBI)MSL1
Genatlas (Paris)MSL1
WikiGenes339287
SOURCE (Princeton)MSL1
Genetics Home Reference (NIH)MSL1
Genomic and cartography
GoldenPath hg38 (UCSC)MSL1  -     chr17:40122537-40136791 +  17q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MSL1  -     17q21.1   [Description]    (hg19-Feb_2009)
EnsemblMSL1 - 17q21.1 [CytoView hg19]  MSL1 - 17q21.1 [CytoView hg38]
Mapping of homologs : NCBIMSL1 [Mapview hg19]  MSL1 [Mapview hg38]
OMIM614801   
Gene and transcription
Genbank (Entrez)AK055378 AK124185 AK125654 AK297619 AL049450
RefSeq transcript (Entrez)NM_001012241
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MSL1
Cluster EST : UnigeneHs.532786 [ NCBI ]
CGAP (NCI)Hs.532786
Alternative Splicing GalleryENSG00000188895
Gene ExpressionMSL1 [ NCBI-GEO ]   MSL1 [ EBI - ARRAY_EXPRESS ]   MSL1 [ SEEK ]   MSL1 [ MEM ]
Gene Expression Viewer (FireBrowse)MSL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)339287
GTEX Portal (Tissue expression)MSL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ68DK7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ68DK7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ68DK7
Splice isoforms : SwissVarQ68DK7
PhosPhoSitePlusQ68DK7
Domains : Interpro (EBI)Msl-1    MSL1_dimer    PEHE_dom   
Domain families : Pfam (Sanger)MSL1_dimer (PF16801)    PEHE (PF15275)   
Domain families : Pfam (NCBI)pfam16801    pfam15275   
Domain families : Smart (EMBL)PEHE (SM01300)  
Conserved Domain (NCBI)MSL1
DMDM Disease mutations339287
Blocks (Seattle)MSL1
PDB (SRS)4B7Y    4B86    4DNC   
PDB (PDBSum)4B7Y    4B86    4DNC   
PDB (IMB)4B7Y    4B86    4DNC   
PDB (RSDB)4B7Y    4B86    4DNC   
Structural Biology KnowledgeBase4B7Y    4B86    4DNC   
SCOP (Structural Classification of Proteins)4B7Y    4B86    4DNC   
CATH (Classification of proteins structures)4B7Y    4B86    4DNC   
SuperfamilyQ68DK7
Human Protein AtlasENSG00000188895
Peptide AtlasQ68DK7
IPIIPI00784883   IPI00787950   IPI00953625   
Protein Interaction databases
DIP (DOE-UCLA)Q68DK7
IntAct (EBI)Q68DK7
FunCoupENSG00000188895
BioGRIDMSL1
STRING (EMBL)MSL1
ZODIACMSL1
Ontologies - Pathways
QuickGOQ68DK7
Ontology : AmiGOnucleoplasm  nucleoplasm  histone H4-K16 acetylation  MSL complex  
Ontology : EGO-EBInucleoplasm  nucleoplasm  histone H4-K16 acetylation  MSL complex  
NDEx NetworkMSL1
Atlas of Cancer Signalling NetworkMSL1
Wikipedia pathwaysMSL1
Orthology - Evolution
OrthoDB339287
GeneTree (enSembl)ENSG00000188895
Phylogenetic Trees/Animal Genes : TreeFamMSL1
HOVERGENQ68DK7
HOGENOMQ68DK7
Homologs : HomoloGeneMSL1
Homology/Alignments : Family Browser (UCSC)MSL1
Gene fusions - Rearrangements
Fusion : MitelmanRARA/MSL1 [17q21.2/17q21.1]  [t(17;17)(q21;q21)]  
Fusion : MitelmanWIPF2/MSL1 [17q21.1/17q21.1]  [t(17;17)(q21;q21)]  
Fusion: TCGARARA 17q21.2 MSL1 17q21.1 BRCA
Fusion: TCGAWIPF2 17q21.1 MSL1 17q21.1 BLCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMSL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MSL1
dbVarMSL1
ClinVarMSL1
1000_GenomesMSL1 
Exome Variant ServerMSL1
ExAC (Exome Aggregation Consortium)MSL1 (select the gene name)
Genetic variants : HAPMAP339287
Genomic Variants (DGV)MSL1 [DGVbeta]
DECIPHERMSL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMSL1 
Mutations
ICGC Data PortalMSL1 
TCGA Data PortalMSL1 
Broad Tumor PortalMSL1
OASIS PortalMSL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMSL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMSL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MSL1
DgiDB (Drug Gene Interaction Database)MSL1
DoCM (Curated mutations)MSL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MSL1 (select a term)
intoGenMSL1
Cancer3DMSL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614801   
Orphanet
MedgenMSL1
Genetic Testing Registry MSL1
NextProtQ68DK7 [Medical]
TSGene339287
GENETestsMSL1
Target ValidationMSL1
Huge Navigator MSL1 [HugePedia]
snp3D : Map Gene to Disease339287
BioCentury BCIQMSL1
ClinGenMSL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD339287
Chemical/Pharm GKB GenePA164723127
Clinical trialMSL1
Miscellaneous
canSAR (ICR)MSL1 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMSL1
EVEXMSL1
GoPubMedMSL1
iHOPMSL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:08:16 CEST 2017

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