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MSL2 (male-specific lethal 2 homolog (Drosophila))

Identity

Alias_namesRNF184
MSL2L1
ring finger protein 184
male-specific lethal 2-like 1 (Drosophila)
Alias_symbol (synonym)FLJ10546
KIAA1585
msl-2
Other aliasMSL-2
HGNC (Hugo) MSL2
LocusID (NCBI) 55167
Atlas_Id 70518
Location 3q22.3  [Link to chromosome band 3q22]
Location_base_pair Starts at 136148918 and ends at 136194468 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EHMT2 (6p21.33) / MSL2 (3q22.3)MSL2 (3q22.3) / MSL2 (3q22.3)MSL2 (3q22.3) / PPP2R3A (3q22.2)
MSL2 (3q22.3) / STAG1 (3q22.3)STAG1 (3q22.3) / MSL2 (3q22.3)TAB1 (22q13.1) / MSL2 (3q22.3)
MSL2 PPP2R3AMSL2 STAG1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MSL2   25544
Cards
Entrez_Gene (NCBI)MSL2  55167  male-specific lethal 2 homolog (Drosophila)
AliasesMSL-2; MSL2L1; RNF184
GeneCards (Weizmann)MSL2
Ensembl hg19 (Hinxton)ENSG00000174579 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174579 [Gene_View]  chr3:136148918-136194468 [Contig_View]  MSL2 [Vega]
ICGC DataPortalENSG00000174579
TCGA cBioPortalMSL2
AceView (NCBI)MSL2
Genatlas (Paris)MSL2
WikiGenes55167
SOURCE (Princeton)MSL2
Genetics Home Reference (NIH)MSL2
Genomic and cartography
GoldenPath hg38 (UCSC)MSL2  -     chr3:136148918-136194468 -  3q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MSL2  -     3q22.3   [Description]    (hg19-Feb_2009)
EnsemblMSL2 - 3q22.3 [CytoView hg19]  MSL2 - 3q22.3 [CytoView hg38]
Mapping of homologs : NCBIMSL2 [Mapview hg19]  MSL2 [Mapview hg38]
OMIM614802   
Gene and transcription
Genbank (Entrez)AB046805 AK001408 AK091956 AK292557 AK302491
RefSeq transcript (Entrez)NM_001145417 NM_018133
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MSL2
Cluster EST : UnigeneHs.18631 [ NCBI ]
CGAP (NCI)Hs.18631
Alternative Splicing GalleryENSG00000174579
Gene ExpressionMSL2 [ NCBI-GEO ]   MSL2 [ EBI - ARRAY_EXPRESS ]   MSL2 [ SEEK ]   MSL2 [ MEM ]
Gene Expression Viewer (FireBrowse)MSL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55167
GTEX Portal (Tissue expression)MSL2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HCI7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HCI7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HCI7
Splice isoforms : SwissVarQ9HCI7
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
PhosPhoSitePlusQ9HCI7
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Msl2-CXC    Msl2_Znf-RING    Tesmin/TSO1-like_CXC    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)MSL2-CXC (PF16682)    zf-RING_10 (PF16685)   
Domain families : Pfam (NCBI)pfam16682    pfam16685   
Domain families : Smart (EMBL)CXC (SM01114)  
Conserved Domain (NCBI)MSL2
DMDM Disease mutations55167
Blocks (Seattle)MSL2
PDB (SRS)4B7Y    4B86   
PDB (PDBSum)4B7Y    4B86   
PDB (IMB)4B7Y    4B86   
PDB (RSDB)4B7Y    4B86   
Structural Biology KnowledgeBase4B7Y    4B86   
SCOP (Structural Classification of Proteins)4B7Y    4B86   
CATH (Classification of proteins structures)4B7Y    4B86   
SuperfamilyQ9HCI7
Human Protein AtlasENSG00000174579
Peptide AtlasQ9HCI7
HPRD08550
IPIIPI00030554   IPI00921864   IPI00946375   IPI00946691   IPI00946768   
Protein Interaction databases
DIP (DOE-UCLA)Q9HCI7
IntAct (EBI)Q9HCI7
FunCoupENSG00000174579
BioGRIDMSL2
STRING (EMBL)MSL2
ZODIACMSL2
Ontologies - Pathways
QuickGOQ9HCI7
Ontology : AmiGOnucleoplasm  zinc ion binding  protein ubiquitination  ligase activity  histone H4-K16 acetylation  ubiquitin protein ligase activity  MSL complex  
Ontology : EGO-EBInucleoplasm  zinc ion binding  protein ubiquitination  ligase activity  histone H4-K16 acetylation  ubiquitin protein ligase activity  MSL complex  
NDEx NetworkMSL2
Atlas of Cancer Signalling NetworkMSL2
Wikipedia pathwaysMSL2
Orthology - Evolution
OrthoDB55167
GeneTree (enSembl)ENSG00000174579
Phylogenetic Trees/Animal Genes : TreeFamMSL2
HOVERGENQ9HCI7
HOGENOMQ9HCI7
Homologs : HomoloGeneMSL2
Homology/Alignments : Family Browser (UCSC)MSL2
Gene fusions - Rearrangements
Fusion: TCGAMSL2 PPP2R3A
Fusion: TCGAMSL2 STAG1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMSL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MSL2
dbVarMSL2
ClinVarMSL2
1000_GenomesMSL2 
Exome Variant ServerMSL2
ExAC (Exome Aggregation Consortium)MSL2 (select the gene name)
Genetic variants : HAPMAP55167
Genomic Variants (DGV)MSL2 [DGVbeta]
DECIPHERMSL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number Analysis=/TDžMSL2 
Mutations
ICGC Data PortalMSL2 
TCGA Data PortalMSL2 
Broad Tumor PortalMSL2
OASIS PortalMSL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMSL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMSL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MSL2
DgiDB (Drug Gene Interaction Database)MSL2
DoCM (Curated mutations)MSL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MSL2 (select a term)
intoGenMSL2
Cancer3DMSL2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614802   
Orphanet
MedgenMSL2
Genetic Testing Registry MSL2
NextProtQ9HCI7 [Medical]
TSGene55167
GENETestsMSL2
Target ValidationMSL2
Huge Navigator MSL2 [HugePedia]
snp3D : Map Gene to Disease55167
BioCentury BCIQMSL2
ClinGenMSL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55167
Chemical/Pharm GKB GenePA164723152
Clinical trialMSL2
Miscellaneous
canSAR (ICR)MSL2 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMSL2
EVEXMSL2
GoPubMedMSL2
iHOPMSL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:31:22 CEST 2017

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