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MSMB (microseminoprotein beta)

Identity

Alias (NCBI)HPC13
IGBF
MSP
MSPB
PN44
PRPS
PSP
PSP-94
PSP57
PSP94
HGNC (Hugo) MSMB
HGNC Alias symbPSP-94
PSP57
PSP94
IGBF
MSP
MSPB
PN44
PRPS
PSP
HGNC Alias namebeta-microseminoprotein
HGNC Previous namemicroseminoprotein, beta-
LocusID (NCBI) 4477
Atlas_Id 41434
Location 10q11.22  [Link to chromosome band 10q11]
Location_base_pair Starts at 46033305 and ends at 46046269 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KCNMA1 (10q22.3) / MSMB (10q11.23)MARCH8 (10q11.21) / MSMB (10q11.23)MSMB (10q11.23) / NCOA4 (10q11.23)
MSMB (10q11.23) / NEFH (22q12.2)RPS6 (9p22.1) / MSMB (10q11.23)KCNMA1 10q22.3 / MSMB 10q11.23
MARCH8 10q11.21 / MSMB 10q11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 4 ]
  Prostate tumors: an overview
MARCH8/MSMB (10q11)
MSMB/NCOA4 (10q11)
t(10;10)(q11;q22) KCNMA1/MSMB

Other Cancer prone implicated (Data extracted from papers in the Atlas) [ 1 ]
  Hereditary prostate cancer

External links

Nomenclature
HGNC (Hugo)MSMB   7372
Cards
Entrez_Gene (NCBI)MSMB    microseminoprotein beta
AliasesHPC13; IGBF; MSP; MSPB; 
PN44; PRPS; PSP; PSP-94; PSP57; PSP94
GeneCards (Weizmann)MSMB
Ensembl hg19 (Hinxton)ENSG00000263639 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000263639 [Gene_View]  ENSG00000263639 [Sequence]  chr10:46033305-46046269 [Contig_View]  MSMB [Vega]
ICGC DataPortalENSG00000263639
TCGA cBioPortalMSMB
AceView (NCBI)MSMB
Genatlas (Paris)MSMB
SOURCE (Princeton)MSMB
Genetics Home Reference (NIH)MSMB
Genomic and cartography
GoldenPath hg38 (UCSC)MSMB  -     chr10:46033305-46046269 -  10q11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MSMB  -     10q11.22   [Description]    (hg19-Feb_2009)
GoldenPathMSMB - 10q11.22 [CytoView hg19]  MSMB - 10q11.22 [CytoView hg38]
ImmunoBaseENSG00000263639
genome Data Viewer NCBIMSMB [Mapview hg19]  
OMIM157145   611928   
Gene and transcription
Genbank (Entrez)AK312108 BC005257 BF680662 BM856408 BT006816
RefSeq transcript (Entrez)NM_002443 NM_138634
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MSMB
Alternative Splicing GalleryENSG00000263639
Gene ExpressionMSMB [ NCBI-GEO ]   MSMB [ EBI - ARRAY_EXPRESS ]   MSMB [ SEEK ]   MSMB [ MEM ]
Gene Expression Viewer (FireBrowse)MSMB [ Firebrowse - Broad ]
GenevisibleExpression of MSMB in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4477
GTEX Portal (Tissue expression)MSMB
Human Protein AtlasENSG00000263639-MSMB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08118   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08118  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08118
Splice isoforms : SwissVarP08118
PhosPhoSitePlusP08118
Domains : Interpro (EBI)PSP94   
Domain families : Pfam (Sanger)PSP94 (PF05825)   
Domain families : Pfam (NCBI)pfam05825   
Conserved Domain (NCBI)MSMB
Blocks (Seattle)MSMB
PDB (RSDB)2IZ3    3IX0   
PDB Europe2IZ3    3IX0   
PDB (PDBSum)2IZ3    3IX0   
PDB (IMB)2IZ3    3IX0   
Structural Biology KnowledgeBase2IZ3    3IX0   
SCOP (Structural Classification of Proteins)2IZ3    3IX0   
CATH (Classification of proteins structures)2IZ3    3IX0   
SuperfamilyP08118
Human Protein Atlas [tissue]ENSG00000263639-MSMB [tissue]
Peptide AtlasP08118
HPRD01143
IPIIPI00414609   IPI00218911   
Protein Interaction databases
DIP (DOE-UCLA)P08118
IntAct (EBI)P08118
BioGRIDMSMB
STRING (EMBL)MSMB
ZODIACMSMB
Ontologies - Pathways
QuickGOP08118
Ontology : AmiGOmolecular_function  protein binding  extracellular space  nucleus  biological_process  
Ontology : EGO-EBImolecular_function  protein binding  extracellular space  nucleus  biological_process  
NDEx NetworkMSMB
Atlas of Cancer Signalling NetworkMSMB
Wikipedia pathwaysMSMB
Orthology - Evolution
OrthoDB4477
GeneTree (enSembl)ENSG00000263639
Phylogenetic Trees/Animal Genes : TreeFamMSMB
HOGENOMP08118
Homologs : HomoloGeneMSMB
Homology/Alignments : Family Browser (UCSC)MSMB
Gene fusions - Rearrangements
Fusion : MitelmanKCNMA1/MSMB [10q22.3/10q11.23]  
Fusion : MitelmanMARCH8/MSMB [10q11.21/10q11.23]  
Fusion : MitelmanMSMB/NCOA4 [10q11.23/10q11.23]  
Fusion PortalKCNMA1 10q22.3 MSMB 10q11.23 BRCA
Fusion PortalMARCH8 10q11.21 MSMB 10q11.23 LUSC
Fusion Cancer (Beijing)RPS6 [9p22.1]  -  MSMB [10q11.23]  [FUSC004556]
Fusion : QuiverMSMB
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMSMB [hg38]
dbVarMSMB
ClinVarMSMB
MonarchMSMB
1000_GenomesMSMB 
Exome Variant ServerMSMB
GNOMAD BrowserENSG00000263639
Varsome BrowserMSMB
Genomic Variants (DGV)MSMB [DGVbeta]
DECIPHERMSMB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMSMB 
Mutations
ICGC Data PortalMSMB 
TCGA Data PortalMSMB 
Broad Tumor PortalMSMB
OASIS PortalMSMB [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMSMB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch MSMB
DgiDB (Drug Gene Interaction Database)MSMB
DoCM (Curated mutations)MSMB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MSMB (select a term)
intoGenMSMB
Cancer3DMSMB(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM157145    611928   
Orphanet903   
DisGeNETMSMB
MedgenMSMB
Genetic Testing Registry MSMB
NextProtP08118 [Medical]
GENETestsMSMB
Target ValidationMSMB
Huge Navigator MSMB [HugePedia]
ClinGenMSMB
Clinical trials, drugs, therapy
MyCancerGenomeMSMB
Protein Interactions : CTD
Pharm GKB GenePA31177
PharosP08118
Clinical trialMSMB
Miscellaneous
canSAR (ICR)MSMB (select the gene name)
HarmonizomeMSMB
DataMed IndexMSMB
Probes
Litterature
PubMed96 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMSMB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Fri Jan 1 18:27:33 CET 2021
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