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MSMB (microseminoprotein beta)

Identity

Alias_namesmicroseminoprotein
Alias_symbol (synonym)PSP-94
PSP57
PSP94
IGBF
MSP
MSPB
PN44
PRPS
PSP
Other aliasHPC13
HGNC (Hugo) MSMB
LocusID (NCBI) 4477
Atlas_Id 41434
Location 10q11.22  [Link to chromosome band 10q11]
Location_base_pair Starts at 46033305 and ends at 46046269 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KCNMA1 (10q22.3) / MSMB (10q11.23)MARCH8 (10q11.21) / MSMB (10q11.23)MSMB (10q11.23) / NCOA4 (10q11.23)
MSMB (10q11.23) / NEFH (22q12.2)RPS6 (9p22.1) / MSMB (10q11.23)KCNMA1 10q22.3 / MSMB 10q11.23
MARCH8 10q11.21 / MSMB 10q11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Prostate tumors: an overview


Other Cancer prone implicated (Data extracted from papers in the Atlas) [ 1 ]
  Hereditary prostate cancer


External links

Nomenclature
HGNC (Hugo)MSMB   7372
Cards
Entrez_Gene (NCBI)MSMB  4477  microseminoprotein beta
AliasesHPC13; IGBF; MSP; MSPB; 
PN44; PRPS; PSP; PSP-94; PSP57; PSP94
GeneCards (Weizmann)MSMB
Ensembl hg19 (Hinxton)ENSG00000263639 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000263639 [Gene_View]  chr10:46033305-46046269 [Contig_View]  MSMB [Vega]
ICGC DataPortalENSG00000263639
TCGA cBioPortalMSMB
AceView (NCBI)MSMB
Genatlas (Paris)MSMB
WikiGenes4477
SOURCE (Princeton)MSMB
Genetics Home Reference (NIH)MSMB
Genomic and cartography
GoldenPath hg38 (UCSC)MSMB  -     chr10:46033305-46046269 -  10q11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MSMB  -     10q11.22   [Description]    (hg19-Feb_2009)
EnsemblMSMB - 10q11.22 [CytoView hg19]  MSMB - 10q11.22 [CytoView hg38]
Mapping of homologs : NCBIMSMB [Mapview hg19]  MSMB [Mapview hg38]
OMIM157145   611928   
Gene and transcription
Genbank (Entrez)AK312108 BC005257 BF680662 BM856408 BT006816
RefSeq transcript (Entrez)NM_002443 NM_138634
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MSMB
Cluster EST : UnigeneHs.255462 [ NCBI ]
CGAP (NCI)Hs.255462
Alternative Splicing GalleryENSG00000263639
Gene ExpressionMSMB [ NCBI-GEO ]   MSMB [ EBI - ARRAY_EXPRESS ]   MSMB [ SEEK ]   MSMB [ MEM ]
Gene Expression Viewer (FireBrowse)MSMB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4477
GTEX Portal (Tissue expression)MSMB
Human Protein AtlasENSG00000263639-MSMB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08118   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08118  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08118
Splice isoforms : SwissVarP08118
PhosPhoSitePlusP08118
Domains : Interpro (EBI)PSP94   
Domain families : Pfam (Sanger)PSP94 (PF05825)   
Domain families : Pfam (NCBI)pfam05825   
Conserved Domain (NCBI)MSMB
DMDM Disease mutations4477
Blocks (Seattle)MSMB
PDB (SRS)2IZ3    3IX0   
PDB (PDBSum)2IZ3    3IX0   
PDB (IMB)2IZ3    3IX0   
PDB (RSDB)2IZ3    3IX0   
Structural Biology KnowledgeBase2IZ3    3IX0   
SCOP (Structural Classification of Proteins)2IZ3    3IX0   
CATH (Classification of proteins structures)2IZ3    3IX0   
SuperfamilyP08118
Human Protein Atlas [tissue]ENSG00000263639-MSMB [tissue]
Peptide AtlasP08118
HPRD01143
IPIIPI00414609   IPI00218911   
Protein Interaction databases
DIP (DOE-UCLA)P08118
IntAct (EBI)P08118
FunCoupENSG00000263639
BioGRIDMSMB
STRING (EMBL)MSMB
ZODIACMSMB
Ontologies - Pathways
QuickGOP08118
Ontology : AmiGOmolecular_function  protein binding  extracellular space  nucleus  biological_process  
Ontology : EGO-EBImolecular_function  protein binding  extracellular space  nucleus  biological_process  
NDEx NetworkMSMB
Atlas of Cancer Signalling NetworkMSMB
Wikipedia pathwaysMSMB
Orthology - Evolution
OrthoDB4477
GeneTree (enSembl)ENSG00000263639
Phylogenetic Trees/Animal Genes : TreeFamMSMB
HOVERGENP08118
HOGENOMP08118
Homologs : HomoloGeneMSMB
Homology/Alignments : Family Browser (UCSC)MSMB
Gene fusions - Rearrangements
Fusion : MitelmanKCNMA1/MSMB [10q22.3/10q11.23]  [t(10;10)(q11;q22)]  
Fusion : MitelmanMARCH8/MSMB [10q11.21/10q11.23]  [t(10;10)(q11;q11)]  
Fusion : MitelmanMSMB/NCOA4 [10q11.23/10q11.23]  [t(10;10)(q11;q11)]  
Fusion: TCGA_MDACCKCNMA1 10q22.3 MSMB 10q11.23 BRCA
Fusion: TCGA_MDACCMARCH8 10q11.21 MSMB 10q11.23 LUSC
Tumor Fusion PortalMSMB
Fusion Cancer (Beijing)RPS6 [9p22.1]  -  MSMB [10q11.23]  [FUSC004556]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMSMB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MSMB
dbVarMSMB
ClinVarMSMB
1000_GenomesMSMB 
Exome Variant ServerMSMB
ExAC (Exome Aggregation Consortium)ENSG00000263639
GNOMAD BrowserENSG00000263639
Genetic variants : HAPMAP4477
Genomic Variants (DGV)MSMB [DGVbeta]
DECIPHERMSMB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMSMB 
Mutations
ICGC Data PortalMSMB 
TCGA Data PortalMSMB 
Broad Tumor PortalMSMB
OASIS PortalMSMB [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMSMB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch MSMB
DgiDB (Drug Gene Interaction Database)MSMB
DoCM (Curated mutations)MSMB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MSMB (select a term)
intoGenMSMB
Cancer3DMSMB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM157145    611928   
Orphanet903   
DisGeNETMSMB
MedgenMSMB
Genetic Testing Registry MSMB
NextProtP08118 [Medical]
TSGene4477
GENETestsMSMB
Target ValidationMSMB
Huge Navigator MSMB [HugePedia]
snp3D : Map Gene to Disease4477
BioCentury BCIQMSMB
ClinGenMSMB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4477
Chemical/Pharm GKB GenePA31177
Clinical trialMSMB
Miscellaneous
canSAR (ICR)MSMB (select the gene name)
Probes
Litterature
PubMed93 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMSMB
EVEXMSMB
GoPubMedMSMB
iHOPMSMB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:24:53 CET 2017

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