MSRA (methionine sulfoxide reductase A)

2003-12-01  

Identity

HGNC
LOCATION
8p23.1
LOCUSID
ALIAS
PMSR
FUSION GENES

Other Information

Locus ID:

NCBI: 4482
MIM: 601250
HGNC: 7377
Ensembl: ENSG00000175806

Variants:

dbSNP: 4482
ClinVar: 4482
TCGA: ENSG00000175806
COSMIC: MSRA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175806ENST00000317173Q9UJ68
ENSG00000175806ENST00000382490Q9UJ68
ENSG00000175806ENST00000441698Q9UJ68
ENSG00000175806ENST00000518255E5RIA9
ENSG00000175806ENST00000521209E9PJ70
ENSG00000175806ENST00000521686H0YAN3
ENSG00000175806ENST00000522907E5RJK1
ENSG00000175806ENST00000528246Q9UJ68

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Protein repairREACTOMER-HSA-5676934

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
195571612009Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.204
195571612009Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.204
204219362010Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.125
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
151991882004Methionine sulfoxide reductase A is important for lens cell viability and resistance to oxidative stress.47
207245812010Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies.47
192375032009Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair.33
203683362010Dual sites of protein initiation control the localization and myristoylation of methionine sulfoxide reductase A.29
176013502007A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.27

Citation

Dessen P

MSRA (methionine sulfoxide reductase A)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41436/msra