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MSRB1 (methionine sulfoxide reductase B1)

Identity

Alias_namesSEPX1
selenoprotein X
Alias_symbol (synonym)SelR
SepR
SelX
Other aliasHSPC270
SELR
SELX
HGNC (Hugo) MSRB1
LocusID (NCBI) 51734
Atlas_Id 43014
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 1938229 and ends at 1943326 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MSRB1   14133
Cards
Entrez_Gene (NCBI)MSRB1  51734  methionine sulfoxide reductase B1
AliasesHSPC270; SELR; SELX; SEPX1; 
SepR
GeneCards (Weizmann)MSRB1
Ensembl hg19 (Hinxton)ENSG00000198736 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198736 [Gene_View]  chr16:1938229-1943326 [Contig_View]  MSRB1 [Vega]
ICGC DataPortalENSG00000198736
TCGA cBioPortalMSRB1
AceView (NCBI)MSRB1
Genatlas (Paris)MSRB1
WikiGenes51734
SOURCE (Princeton)MSRB1
Genetics Home Reference (NIH)MSRB1
Genomic and cartography
GoldenPath hg38 (UCSC)MSRB1  -     chr16:1938229-1943326 -  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MSRB1  -     16p13.3   [Description]    (hg19-Feb_2009)
EnsemblMSRB1 - 16p13.3 [CytoView hg19]  MSRB1 - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBIMSRB1 [Mapview hg19]  MSRB1 [Mapview hg38]
OMIM606216   
Gene and transcription
Genbank (Entrez)AF161388 AF166124 AF187272 AI183441 AK026128
RefSeq transcript (Entrez)NM_016332
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MSRB1
Cluster EST : UnigeneHs.655346 [ NCBI ]
CGAP (NCI)Hs.655346
Alternative Splicing GalleryENSG00000198736
Gene ExpressionMSRB1 [ NCBI-GEO ]   MSRB1 [ EBI - ARRAY_EXPRESS ]   MSRB1 [ SEEK ]   MSRB1 [ MEM ]
Gene Expression Viewer (FireBrowse)MSRB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51734
GTEX Portal (Tissue expression)MSRB1
Human Protein AtlasENSG00000198736-MSRB1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZV6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZV6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZV6
Splice isoforms : SwissVarQ9NZV6
Catalytic activity : Enzyme1.8.4.- [ Enzyme-Expasy ]   1.8.4.-1.8.4.- [ IntEnz-EBI ]   1.8.4.- [ BRENDA ]   1.8.4.- [ KEGG ]   
PhosPhoSitePlusQ9NZV6
Domaine pattern : Prosite (Expaxy)MSRB (PS51790)   
Domains : Interpro (EBI)Met_Sox_Rdtase    Met_Sox_Rdtase_MsrB    Mss4-like   
Domain families : Pfam (Sanger)SelR (PF01641)   
Domain families : Pfam (NCBI)pfam01641   
Conserved Domain (NCBI)MSRB1
DMDM Disease mutations51734
Blocks (Seattle)MSRB1
PDB (SRS)3MAO   
PDB (PDBSum)3MAO   
PDB (IMB)3MAO   
PDB (RSDB)3MAO   
Structural Biology KnowledgeBase3MAO   
SCOP (Structural Classification of Proteins)3MAO   
CATH (Classification of proteins structures)3MAO   
SuperfamilyQ9NZV6
Human Protein Atlas [tissue]ENSG00000198736-MSRB1 [tissue]
Peptide AtlasQ9NZV6
HPRD12095
IPIIPI00021576   IPI00797026   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZV6
IntAct (EBI)Q9NZV6
FunCoupENSG00000198736
BioGRIDMSRB1
STRING (EMBL)MSRB1
ZODIACMSRB1
Ontologies - Pathways
QuickGOQ9NZV6
Ontology : AmiGOactin binding  cellular_component  nucleus  cytosol  response to oxidative stress  zinc ion binding  actin cytoskeleton  actin filament polymerization  protein repair  protein repair  peptide-methionine (R)-S-oxide reductase activity  peptide-methionine (R)-S-oxide reductase activity  innate immune response  oxidation-reduction process  methionine-R-sulfoxide reductase activity  
Ontology : EGO-EBIactin binding  cellular_component  nucleus  cytosol  response to oxidative stress  zinc ion binding  actin cytoskeleton  actin filament polymerization  protein repair  protein repair  peptide-methionine (R)-S-oxide reductase activity  peptide-methionine (R)-S-oxide reductase activity  innate immune response  oxidation-reduction process  methionine-R-sulfoxide reductase activity  
NDEx NetworkMSRB1
Atlas of Cancer Signalling NetworkMSRB1
Wikipedia pathwaysMSRB1
Orthology - Evolution
OrthoDB51734
GeneTree (enSembl)ENSG00000198736
Phylogenetic Trees/Animal Genes : TreeFamMSRB1
HOVERGENQ9NZV6
HOGENOMQ9NZV6
Homologs : HomoloGeneMSRB1
Homology/Alignments : Family Browser (UCSC)MSRB1
Gene fusions - Rearrangements
Tumor Fusion PortalMSRB1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMSRB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MSRB1
dbVarMSRB1
ClinVarMSRB1
1000_GenomesMSRB1 
Exome Variant ServerMSRB1
ExAC (Exome Aggregation Consortium)ENSG00000198736
GNOMAD BrowserENSG00000198736
Genetic variants : HAPMAP51734
Genomic Variants (DGV)MSRB1 [DGVbeta]
DECIPHERMSRB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMSRB1 
Mutations
ICGC Data PortalMSRB1 
TCGA Data PortalMSRB1 
Broad Tumor PortalMSRB1
OASIS PortalMSRB1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMSRB1
BioMutasearch MSRB1
DgiDB (Drug Gene Interaction Database)MSRB1
DoCM (Curated mutations)MSRB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MSRB1 (select a term)
intoGenMSRB1
Cancer3DMSRB1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606216   
Orphanet
DisGeNETMSRB1
MedgenMSRB1
Genetic Testing Registry MSRB1
NextProtQ9NZV6 [Medical]
TSGene51734
GENETestsMSRB1
Target ValidationMSRB1
Huge Navigator MSRB1 [HugePedia]
snp3D : Map Gene to Disease51734
BioCentury BCIQMSRB1
ClinGenMSRB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51734
Chemical/Pharm GKB GenePA37848
Clinical trialMSRB1
Miscellaneous
canSAR (ICR)MSRB1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMSRB1
EVEXMSRB1
GoPubMedMSRB1
iHOPMSRB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:24:54 CET 2017

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