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MSRB2 (methionine sulfoxide reductase B2)

Identity

Alias (NCBI)CBS-1
CBS1
CGI-131
MSRB
PILB
HGNC (Hugo) MSRB2
HGNC Alias symbPILB
CGI-131
CBS1
CBS-1
HGNC Previous nameMSRB
HGNC Previous namemethionine sulfoxide reductase B
LocusID (NCBI) 22921
Atlas_Id 43001
Location 10p12.2  [Link to chromosome band 10p12]
Location_base_pair Starts at 23095579 and ends at 23122013 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MSRB2 (10p12.2) / MALRD1 (10p12.31)MSRB2 10p12.2 C10orf112

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MSRB2   17061
Cards
Entrez_Gene (NCBI)MSRB2    methionine sulfoxide reductase B2
AliasesCBS-1; CBS1; CGI-131; MSRB; 
PILB
GeneCards (Weizmann)MSRB2
Ensembl hg19 (Hinxton)ENSG00000148450 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148450 [Gene_View]  ENSG00000148450 [Sequence]  chr10:23095579-23122013 [Contig_View]  MSRB2 [Vega]
ICGC DataPortalENSG00000148450
TCGA cBioPortalMSRB2
AceView (NCBI)MSRB2
Genatlas (Paris)MSRB2
SOURCE (Princeton)MSRB2
Genetics Home Reference (NIH)MSRB2
Genomic and cartography
GoldenPath hg38 (UCSC)MSRB2  -     chr10:23095579-23122013 +  10p12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MSRB2  -     10p12.2   [Description]    (hg19-Feb_2009)
GoldenPathMSRB2 - 10p12.2 [CytoView hg19]  MSRB2 - 10p12.2 [CytoView hg38]
ImmunoBaseENSG00000148450
Genome Data Viewer NCBIMSRB2 [Mapview hg19]  
OMIM613782   
Gene and transcription
Genbank (Entrez)AF122004 AF151889 BC018030 BC066305 BC117471
RefSeq transcript (Entrez)NM_012228
Consensus coding sequences : CCDS (NCBI)MSRB2
Gene ExpressionMSRB2 [ NCBI-GEO ]   MSRB2 [ EBI - ARRAY_EXPRESS ]   MSRB2 [ SEEK ]   MSRB2 [ MEM ]
Gene Expression Viewer (FireBrowse)MSRB2 [ Firebrowse - Broad ]
GenevisibleExpression of MSRB2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22921
GTEX Portal (Tissue expression)MSRB2
Human Protein AtlasENSG00000148450-MSRB2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3D2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y3D2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3D2
PhosPhoSitePlusQ9Y3D2
Domaine pattern : Prosite (Expaxy)MSRB (PS51790)   
Domains : Interpro (EBI)Met_Sox_Rdtase    Met_Sox_Rdtase_MsrB    Mss4-like_sf   
Domain families : Pfam (Sanger)SelR (PF01641)   
Domain families : Pfam (NCBI)pfam01641   
Conserved Domain (NCBI)MSRB2
SuperfamilyQ9Y3D2
AlphaFold pdb e-kbQ9Y3D2   
Human Protein Atlas [tissue]ENSG00000148450-MSRB2 [tissue]
HPRD17606
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3D2
IntAct (EBI)Q9Y3D2
BioGRIDMSRB2
STRING (EMBL)MSRB2
ZODIACMSRB2
Ontologies - Pathways
QuickGOQ9Y3D2
Ontology : AmiGOactin binding  protein binding  cytoplasm  mitochondrion  cytosol  response to oxidative stress  zinc ion binding  actin filament polymerization  protein repair  protein repair  peptide-methionine (R)-S-oxide reductase activity  peptide-methionine (R)-S-oxide reductase activity  L-methionine-(R)-S-oxide reductase activity  
Ontology : EGO-EBIactin binding  protein binding  cytoplasm  mitochondrion  cytosol  response to oxidative stress  zinc ion binding  actin filament polymerization  protein repair  protein repair  peptide-methionine (R)-S-oxide reductase activity  peptide-methionine (R)-S-oxide reductase activity  L-methionine-(R)-S-oxide reductase activity  
NDEx NetworkMSRB2
Atlas of Cancer Signalling NetworkMSRB2
Wikipedia pathwaysMSRB2
Orthology - Evolution
OrthoDB22921
GeneTree (enSembl)ENSG00000148450
Phylogenetic Trees/Animal Genes : TreeFamMSRB2
Homologs : HomoloGeneMSRB2
Homology/Alignments : Family Browser (UCSC)MSRB2
Gene fusions - Rearrangements
Fusion : MitelmanMSRB2/MALRD1 [10p12.2/10p12.31]  
Fusion : QuiverMSRB2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMSRB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MSRB2
dbVarMSRB2
ClinVarMSRB2
MonarchMSRB2
1000_GenomesMSRB2 
Exome Variant ServerMSRB2
GNOMAD BrowserENSG00000148450
Varsome BrowserMSRB2
ACMGMSRB2 variants
VarityQ9Y3D2
Genomic Variants (DGV)MSRB2 [DGVbeta]
DECIPHERMSRB2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMSRB2 
Mutations
ICGC Data PortalMSRB2 
TCGA Data PortalMSRB2 
Broad Tumor PortalMSRB2
OASIS PortalMSRB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMSRB2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMSRB2
Mutations and Diseases : HGMDMSRB2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMSRB2
DgiDB (Drug Gene Interaction Database)MSRB2
DoCM (Curated mutations)MSRB2
CIViC (Clinical Interpretations of Variants in Cancer)MSRB2
Cancer3DMSRB2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613782   
Orphanet
DisGeNETMSRB2
MedgenMSRB2
Genetic Testing Registry MSRB2
NextProtQ9Y3D2 [Medical]
GENETestsMSRB2
Target ValidationMSRB2
Huge Navigator MSRB2 [HugePedia]
ClinGenMSRB2
Clinical trials, drugs, therapy
MyCancerGenomeMSRB2
Protein Interactions : CTDMSRB2
Pharm GKB GenePA134979691
PharosQ9Y3D2
Clinical trialMSRB2
Miscellaneous
canSAR (ICR)MSRB2
HarmonizomeMSRB2
DataMed IndexMSRB2
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMSRB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:21:26 CEST 2021

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